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5-Bromo-4-chloro-2-methoxybenzonitrile
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5-Bromo-4-chloro-2-methoxybenzonitrile
Artikel-Nr:
(BOSSBS-9084R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9084R-A488
Lokale Artikelnummer::
BOSSBS-9084R-A488
Beschreibung:
Belonging to the F-box family of proteins, FBXO35 (F-box only protein 35), also designated F-box and WD-40 domain-containing protein 12 (FBXW12 or FBXO12), is a 464 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO35 can directly interact with Skp1 p19 and CUL-1. FBXO35 is ubiquitously expressed at low levels in most human tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9084R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9084R
Lokale Artikelnummer::
BOSSBS-9084R
Beschreibung:
Belonging to the F-box family of proteins, FBXO35 (F-box only protein 35), also designated F-box and WD-40 domain-containing protein 12 (FBXW12 or FBXO12), is a 464 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO35 can directly interact with Skp1 p19 and CUL-1. FBXO35 is ubiquitously expressed at low levels in most human tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11153R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11153R-CY3
Lokale Artikelnummer::
BOSSBS-11153R-CY3
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB12 (Protocadherin beta 12) is a 795 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB12) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB12 is a single-pass type I membrane protein that contains six cadherin domains. PCDHB12 may participate in the establishment and maintenance of specific neuronal connections in the brain.
VE:
1 * 100 µl
Artikel-Nr:
(REST30279)
Lieferant:
Restek
Hersteller-Artikelnummer::
30279
Lokale Artikelnummer::
REST30279
Beschreibung:
Organic Standard, cis-1,2-Dichloroethene, 1 ml/ampoule
VE:
1 * 1 mL
Artikel-Nr:
(KRAF01521.3700)
Lieferant:
Bernd Kraft
Hersteller-Artikelnummer::
01521.3700
Lokale Artikelnummer::
KRAF01521.3700
Beschreibung:
Kaliumdichromat 0.2 mol/l (1.2 N) in wässriger Lösung
VE:
1 * 1 L
Artikel-Nr:
(VISIMTA 330)
Lieferant:
VISION ENGINEERING
Hersteller-Artikelnummer::
MTA 330
Lokale Artikelnummer::
VISIMTA 330
Beschreibung:
Accessory for microscopes, Stromversorgung, 12 V, 3 A
VE:
1 * 1 ST
Lieferant:
APPLICHEM
Beschreibung:
Pikrinsäure 12 g/l in wässriger Lösung
Artikel-Nr:
(BOSSBS-11952R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11952R-A488
Lokale Artikelnummer::
BOSSBS-11952R-A488
Beschreibung:
The four isoforms of potassium/chloride co-transport channels (KCC) belong to a superfamily of cation-chloride co-transporters involved in cell volume maintenance. Nitric oxide (NO) donors activate KCCs, while inhibitors of the cGMP pathway prevent NO donor activation. The ubiquitously expressed KCC1 contains 12 transmembrane domains with both cytoplasmic N and C terminal domains. KCC2 expression is limited to neuronal tissues by a restrictive element similar to the neuronal-restrictive silencing factor. In neurons, KCC2 expression is correlated with an inhibitory response to GABA, while the absence of KCC2 is necessary for an unusual excitatory response to GABA. Alterations of KCC2 expression in the inferior colliculus of rat brain may be related to seizure susceptibility. Conversely, KCC3 is not suspected to play a major role in epilepsy. The two splice variants of KCC3, KCC3a and KCC3b, are predominantly expressed in brain and kidney, respectively, while KCC4 is expressed in muscle, brain, lung, heart and kidney.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11952R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11952R-CY3
Lokale Artikelnummer::
BOSSBS-11952R-CY3
Beschreibung:
The four isoforms of potassium/chloride co-transport channels (KCC) belong to a superfamily of cation-chloride co-transporters involved in cell volume maintenance. Nitric oxide (NO) donors activate KCCs, while inhibitors of the cGMP pathway prevent NO donor activation. The ubiquitously expressed KCC1 contains 12 transmembrane domains with both cytoplasmic N and C terminal domains. KCC2 expression is limited to neuronal tissues by a restrictive element similar to the neuronal-restrictive silencing factor. In neurons, KCC2 expression is correlated with an inhibitory response to GABA, while the absence of KCC2 is necessary for an unusual excitatory response to GABA. Alterations of KCC2 expression in the inferior colliculus of rat brain may be related to seizure susceptibility. Conversely, KCC3 is not suspected to play a major role in epilepsy. The two splice variants of KCC3, KCC3a and KCC3b, are predominantly expressed in brain and kidney, respectively, while KCC4 is expressed in muscle, brain, lung, heart and kidney.
VE:
1 * 100 µl
Artikel-Nr:
(PROOMM1273.06)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
MM1273.06
Lokale Artikelnummer::
PROOMM1273.06
Beschreibung:
Organic Standard, 3-Piperazin-1-yl-1,2-benzisothiazole hydrochloride
VE:
1 * 100 mg
Lieferant:
COWIE
Beschreibung:
Universal replacement lock nut for 12 mm shafts
Lieferant:
Honeywell Chemicals
Beschreibung:
1,2-Dihydroxybenzol-3,5-disulfonsäure Dinatriumsalz Monohydrat Indikator für die Komplexometrie, Fluka™
Artikel-Nr:
(USBI146275)
Lieferant:
US Biological
Hersteller-Artikelnummer::
146275
Lokale Artikelnummer::
USBI146275
Beschreibung:
Anti-TNPO3 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Lieferant:
Agilent
Beschreibung:
Adjustable wrench, 12", for use with regulators
Artikel-Nr:
(PROOMM0548.01)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
MM0548.01
Lokale Artikelnummer::
PROOMM0548.01
Beschreibung:
Organic Standard, (2RS)-2-[(1,2-diphenyldiazanyl)carbonyl]hexanoic acid
VE:
1 * 100 mg
Artikel-Nr:
(BOSSBS-9084R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9084R-A555
Lokale Artikelnummer::
BOSSBS-9084R-A555
Beschreibung:
Belonging to the F-box family of proteins, FBXO35 (F-box only protein 35), also designated F-box and WD-40 domain-containing protein 12 (FBXW12 or FBXO12), is a 464 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO35 can directly interact with Skp1 p19 and CUL-1. FBXO35 is ubiquitously expressed at low levels in most human tissues.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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