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3,3'-Dimethylbenzidin+Dihydrochorid
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3,3'-Dimethylbenzidin+Dihydrochorid
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 33-55 kDa, identified as CD37 (Workshop V; Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg ) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL).
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 33-37 kDa, identified as CD20 (Workshop V; Code CD20.12). B9E9 recognizes extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression.
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 33-55 kDa, identified as CD53 (Workshop VI; Code N-L033). It is expressed on monocytes and macrophages, dendritic cells, osteoblasts and osteoclasts, and on T and B cells from every stage of differentiation but is absent from platelets, red blood cells. CD53 appears to be the marker with widest reactivity as well as the marker with the strictest specificity to hematopoietic cells. CD53 is a type III membrane with both termini in the cytoplasm and two loops in the extracellular environment. This molecule, in common with other members of tetraspan family, is involved in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. CD53 crosslinking induces calcium flux on human monocyte and B cells. Cross-linking of CD53 promotes activation of resting human B-lymphocytes. This MAb recognizes CD53 transfected cells and partially inhibits T-cell proliferation induced by CD3 antibody (clone: UCHT1).
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 33-55 kDa, identified as CD53 (Workshop VI; Code N-L033). It is expressed on monocytes and macrophages, dendritic cells, osteoblasts and osteoclasts, and on T and B cells from every stage of differentiation but is absent from platelets, red blood cells. CD53 appears to be the marker with widest reactivity as well as the marker with the strictest specificity to hematopoietic cells. CD53 is a type III membrane with both termini in the cytoplasm and two loops in the extracellular environment. This molecule, in common with other members of tetraspan family, is involved in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. CD53 crosslinking induces calcium flux on human monocyte and B cells. Cross-linking of CD53 promotes activation of resting human B-lymphocytes. This MAb recognizes CD53 transfected cells and partially inhibits T-cell proliferation induced by CD3 antibody (clone: UCHT1).
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 33-55 kDa, identified as CD53 (Workshop VI; Code N-L033). It is expressed on monocytes and macrophages, dendritic cells, osteoblasts and osteoclasts, and on T and B cells from every stage of differentiation but is absent from platelets, red blood cells. CD53 appears to be the marker with widest reactivity as well as the marker with the strictest specificity to hematopoietic cells. CD53 is a type III membrane with both termini in the cytoplasm and two loops in the extracellular environment. This molecule, in common with other members of tetraspan family, is involved in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. CD53 crosslinking induces calcium flux on human monocyte and B cells. Cross-linking of CD53 promotes activation of resting human B-lymphocytes. This MAb recognizes CD53 transfected cells and partially inhibits T-cell proliferation induced by CD3 antibody (clone: UCHT1).
Artikel-Nr:
(BOSSBS-6023R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6023R-A647
Lokale Artikelnummer::
BOSSBS-6023R-A647
Beschreibung:
Bone marrow stromal cell antigen 1 (BST1) is a pleiotropic ectoenzyme which belongs to the CD38 family and to the growing number of leukocyte surface molecules known to act independently as both receptors and enzymes. The BST1 molecule displays two distinct domains in its extracellular component. The first is implicated in the enzymic activities of the molecule (it synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores) and the second domain has adhesion/signalling properties.Bone marrow stromal cell antigen 1 facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.
VE:
1 * 100 µl
Artikel-Nr:
(ABNOMAB13720)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB13720
Lokale Artikelnummer::
ABNOMAB13720
Beschreibung:
Mouse monoclonal antibody raised against human CD3E.
VE:
1 * 100 Assays
Artikel-Nr:
(ABNOMAB13721)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB13721
Lokale Artikelnummer::
ABNOMAB13721
Beschreibung:
Mouse monoclonal antibody raised against human CD3E.
VE:
1 * 100 Assays
Artikel-Nr:
(USBI129108)
Lieferant:
US Biological
Hersteller-Artikelnummer::
129108
Lokale Artikelnummer::
USBI129108
Beschreibung:
Anti-LIN7A Mouse Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-075)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-075
Lokale Artikelnummer::
PRSI91-075
Beschreibung:
Interleukin-33 (IL-33) was initially discovered as a nuclear factor NF-HEV abundantly expressed in high endothelial venules. It is a 30-32 kD pro-inflammatory protein with intracellular and extracellular activities and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 is highly and selectively expressed by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyers's patches, and lymph nodes. It contains a bipartite nuclear localization signal at the C-terminus, and is targeted to the nucleus when ectopically expressed in human umbilical vein endothelial cells (HUVECs) and HeLa cells. The C-terminal fragment, corresponding to mature IL-33, binds and triggers signaling. IL-33 mediates its biological effects via Toll-interleukin 1 (IL-1) receptor (TIR) domain-containing receptor ST2, activates NF-kappaB and MAP kinases, and drives production of T(H)2-associated cytokines from in vitro polarized T(H)2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs. Human IL-33 is 270 amino acids in length.
VE:
1 * 50 µG
Artikel-Nr:
(PROOMM0232.02)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
MM0232.02
Lokale Artikelnummer::
PROOMM0232.02
Beschreibung:
Organic Standard, (2S,5R,6R)-6-[[(2S)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
VE:
1 * 100 mg
Artikel-Nr:
(NEUB0294-50-0150)
Lieferant:
NEUBERT VOLUME GLASSWAERE
Hersteller-Artikelnummer::
0294-50-0150
Lokale Artikelnummer::
NEUB0294-50-0150
Beschreibung:
Borosilicate glass, grade 3.3, with glass stopper.
VE:
1 * 1 ST
Lieferant:
MURRAY S
Beschreibung:
Borosilicate glass, grade 3.3, SAMCO '33'. Medium walled.
Artikel-Nr:
(ABNOMAB13722)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB13722
Lokale Artikelnummer::
ABNOMAB13722
Beschreibung:
Mouse monoclonal antibody raised against human CD3E.
VE:
1 * 100 µG
Artikel-Nr:
(EHERC12965400)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C12965400
Lokale Artikelnummer::
EHERC12965400
Beschreibung:
Kongorot
VE:
1 * 0,1 g
Artikel-Nr:
(MOLE15685521-25G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
15685521-25G
Lokale Artikelnummer::
MOLE15685521-25G
Beschreibung:
o-Kresolphthalein
VE:
1 * 25 g
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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