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3,3-Dimethoxypropiononitril
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3,3-Dimethoxypropiononitril
Artikel-Nr:
(BOSSBS-4211R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4211R-CY5.5
Lokale Artikelnummer::
BOSSBS-4211R-CY5.5
Beschreibung:
Core component of multiple cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the BCR complex depends on the BTB domain-containing protein as the substrate recognition component. BCR(KLHL42) is involved in ubiquitination of KATNA1. BCR(SPOP) is involved in ubiquitination of BMI1/PCGF4, BRMS1, H2AFY and DAXX, GLI2 and GLI3. Can also form a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL; these complexes have lower ubiquitin ligase activity. BCR(KLHL9-KLHL13) controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. BCR(KLHL12) is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). BCR(KLHL3) acts as a regulator of ion transport in the distal nephron; by mediating ubiquitination of WNK4. The BCR(KLHL20) E3 ubiquitin ligase complex is involved in interferon response and anterograde Golgi to endosome transport: it mediates both ubiquitination leading to degradation and 'Lys-33'-linked ubiquitination (PubMed:20389280, PubMed:21840486, PubMed:21670212, PubMed:24768539).
VE:
1 * 100 µl
Lieferant:
LAUDA
Beschreibung:
Kältethermostate mit Kurztext-Menüsteuerung für benutzerfreundliche Bedienung. Verschiedene Schnittstellenmodule als Zubehör erhältlich. Alle Modelle sind mit Luft- oder Wasserkühlung erhältlich.
Lieferant:
Sigma-Aldrich
Beschreibung:
Linolsäure, Sigma-Aldrich®
Lieferant:
Spectrum Chemical
Beschreibung:
Denatonium Benzoate, Anhydrous, Granular, NF is used as a denaturant and masking agent.
Lieferant:
LAUDA
Beschreibung:
Cooling thermostats with menu navigation in plain text for user friendly operation. Various interface modules are available as accessories. All models are available as air or water-cooled versions. They are similar in specifications with the ECO model thermostats, in addition these models comes with natural refrigerant.
Artikel-Nr:
(PRSI76-004)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-004
Lokale Artikelnummer::
PRSI76-004
Beschreibung:
The 2H7 monoclonal antibody specifically reacts with human CD20, a 33 to 37 kDa B-lymphocyte surface molecule. CD20 is an unglycosylated four-transmembrane phosphoprotein expressed by B cells in all stage of development, except the final plasma cells. It has been reported that the molecule is involved in B cell activation and has also been observed on a subset of circulating T lymphocytes.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(705-0989)
Lieferant:
Hach
Hersteller-Artikelnummer::
BU2000XX65665
Lokale Artikelnummer::
HACHBU2000XX65665
Beschreibung:
Portable water sampler using pressure-vacuum technology. Combines small dimensions by offering the 24×1 l bottle option for glass as well as plastic bottles or 25 l composite PE bottle. Enables the option of 24×1 l or 1×25 l PE sample bottles, respectively 24×1 l or 1×20 l glass sample bottles, in combination with an active cooled sampler base. This is especially interesting for sampling in accordance to local regulation (24 × hourly mixed sample/daily mixed sample). Cleaning efforts are reduced to a minimum due to the new designed vat sample distributor and the standard round sample bottles. The sampler offers two cooling options for ensuring a sample storage at 4 °C: passive with ice packs or active with an integrated cooling machine including autarkic temperature control. The pressure-vacuum sampler is ISO 5667 compliant. To avoid cross contamination, the system is purged before and after each sample is taken. The compact, weatherproof housing made of PE plastic ensures failure-free operation over many years and often changing installation locations. Even in extremely corrosive applications. All programming features of stationary sampler products are available.
VE:
1 * 1 ST
Artikel-Nr:
(SIALC3105-50UG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
C3105-50UG
Lokale Artikelnummer::
SIALC3105-50UG
Beschreibung:
135 times higher luminescence intensity than native coelenterazine
VE:
1 * 50 µG
Lieferant:
WITEG LABORTECHNIK
Beschreibung:
DURAN®. Passend für Vakuumexsikkatoren Type WERTEX.
Lieferant:
Portwest Clothing
Beschreibung:
Mit der Einführung der WX3 Eco Stretch Holsterhose setzt Portwest weiterhin neue Maßstäbe im Bereich der nachhaltigen Arbeitskleidung. Diese Hose mit aktiver Passform besteht aus hochwertigem, recyceltem Polyester mit zusätzlichem Stretch, um maximale Bewegungsfreiheit bei der Arbeit zu gewährleisten.
Artikel-Nr:
(ENAMEN300100417.1G)
Lieferant:
SIA ENAMINE
Hersteller-Artikelnummer::
EN300100417.1G
Lokale Artikelnummer::
ENAMEN300100417.1G
Beschreibung:
3,5-Dimethyl-1H-pyrazol-1-methanol
VE:
1 * 1 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-4211R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4211R
Lokale Artikelnummer::
BOSSBS-4211R
Beschreibung:
Core component of multiple cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the BCR complex depends on the BTB domain-containing protein as the substrate recognition component. BCR(KLHL42) is involved in ubiquitination of KATNA1. BCR(SPOP) is involved in ubiquitination of BMI1/PCGF4, BRMS1, H2AFY and DAXX, GLI2 and GLI3. Can also form a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL; these complexes have lower ubiquitin ligase activity. BCR(KLHL9-KLHL13) controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. BCR(KLHL12) is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). BCR(KLHL3) acts as a regulator of ion transport in the distal nephron; by mediating ubiquitination of WNK4. The BCR(KLHL20) E3 ubiquitin ligase complex is involved in interferon response and anterograde Golgi to endosome transport: it mediates both ubiquitination leading to degradation and 'Lys-33'-linked ubiquitination (PubMed:20389280, PubMed:21840486, PubMed:21670212, PubMed:24768539).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4211R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4211R-CY7
Lokale Artikelnummer::
BOSSBS-4211R-CY7
Beschreibung:
Core component of multiple cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the BCR complex depends on the BTB domain-containing protein as the substrate recognition component. BCR(KLHL42) is involved in ubiquitination of KATNA1. BCR(SPOP) is involved in ubiquitination of BMI1/PCGF4, BRMS1, H2AFY and DAXX, GLI2 and GLI3. Can also form a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL; these complexes have lower ubiquitin ligase activity. BCR(KLHL9-KLHL13) controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. BCR(KLHL12) is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). BCR(KLHL3) acts as a regulator of ion transport in the distal nephron; by mediating ubiquitination of WNK4. The BCR(KLHL20) E3 ubiquitin ligase complex is involved in interferon response and anterograde Golgi to endosome transport: it mediates both ubiquitination leading to degradation and 'Lys-33'-linked ubiquitination (PubMed:20389280, PubMed:21840486, PubMed:21670212, PubMed:24768539).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4211R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4211R-HRP
Lokale Artikelnummer::
BOSSBS-4211R-HRP
Beschreibung:
Core component of multiple cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the BCR complex depends on the BTB domain-containing protein as the substrate recognition component. BCR(KLHL42) is involved in ubiquitination of KATNA1. BCR(SPOP) is involved in ubiquitination of BMI1/PCGF4, BRMS1, H2AFY and DAXX, GLI2 and GLI3. Can also form a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL; these complexes have lower ubiquitin ligase activity. BCR(KLHL9-KLHL13) controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. BCR(KLHL12) is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). BCR(KLHL3) acts as a regulator of ion transport in the distal nephron; by mediating ubiquitination of WNK4. The BCR(KLHL20) E3 ubiquitin ligase complex is involved in interferon response and anterograde Golgi to endosome transport: it mediates both ubiquitination leading to degradation and 'Lys-33'-linked ubiquitination (PubMed:20389280, PubMed:21840486, PubMed:21670212, PubMed:24768539).
VE:
1 * 100 µl
Artikel-Nr:
(40867-50G)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
40867-50G
Lokale Artikelnummer::
HONC40867-50G
Beschreibung:
Ammoniumhydrogencarbonat ≥99% Eluentzusatz, für die LC-MS, Fluka™
VE:
1 * 50 g
Artikel-Nr:
(111-1905)
Lieferant:
UVEX
Hersteller-Artikelnummer::
2600.202
Lokale Artikelnummer::
UVEX2600.202
Beschreibung:
Dieser Gehörschutz zur Befestigung an Helmen ist geeignet für Umgebungen mit mittlerem Geräuschpegel (33 dB). Er kann an den folgenden uvex Schutzhelmen angebracht werden: uvex pheos B-WR, uvex pheos alpine, uvex airwing und uvex superboss (weitere Adaptersysteme zur Kombination mit Schutzhelmen und Visieren sind auf Anfrage erhältlich). Zwei Modelle sind speziell für die Verwendung mit dem uvex pheos Helmsystem vorgesehen.
VE:
1 * 1 ST
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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