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(1-Phenyl-1H-pyrazol-4-yl)methanol
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(1-Phenyl-1H-pyrazol-4-yl)methanol
Artikel-Nr:
(BOSSBS-0290R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0290R-HRP
Lokale Artikelnummer::
BOSSBS-0290R-HRP
Beschreibung:
The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit (95 kDa) possesses a single transmembrane domain, whereas the alpha subunit (135 kDa) is completely extracellular. The insulin receptor exhibits receptor tyrosine kinase (RTK) activity. RTKs are single pass transmembrane receptors that possess intrinsic cytoplasmic enzymatic activity, catalyzing the transfer of the gamma phosphate of ATP to tyrosine residues in protein substrates. RTKs are essential components of signal transduction pathways that affect cell proliferation, differentiation, migration and metabolism.Included in this large protein family are the insulin receptor and the receptors for growth factors such as epidermal growth factor, fibroblast growth factor and vascular endothelial growth factor. Receptor activation occurs through ligand binding, which facilitates receptor dimerization and autophosphorylation of specific tyrosine residues in the cytoplasmic portion. The interaction of insulin with the alpha subunit of the insulin receptor activates the protein tyrosine kinase of the beta subunit, which then undergoes an autophosphorylation that increases its tyrosine kinase activity. Three adapter proteins, IRS1, IRS2 and Shc, become phosphorylated on tyrosine residues following insulin receptor activation. These three phosphorylated proteins then interact with SH2 domain containing signaling proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5453R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5453R-A350
Lokale Artikelnummer::
BOSSBS-5453R-A350
Beschreibung:
The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit (95 kDa) possesses a single transmembrane domain, whereas the alpha subunit (135 kDa) is completely extracellular. The insulin receptor exhibits receptor tyrosine kinase (RTK) activity. RTKs are single pass transmembrane receptors that possess intrinsic cytoplasmic enzymatic activity, catalyzing the transfer of the gamma phosphate of ATP to tyrosine residues in protein substrates. RTKs are essential components of signal transduction pathways that affect cell proliferation, differentiation, migration and metabolism.Included in this large protein family are the insulin receptor and the receptors for growth factors such as epidermal growth factor, fibroblast growth factor and vascular endothelial growth factor. Receptor activation occurs through ligand binding, which facilitates receptor dimerization and autophosphorylation of specific tyrosine residues in the cytoplasmic portion. The interaction of insulin with the alpha subunit of the insulin receptor activates the protein tyrosine kinase of the beta subunit, which then undergoes an autophosphorylation that increases its tyrosine kinase activity. Three adapter proteins, IRS1, IRS2 and Shc, become phosphorylated on tyrosine residues following insulin receptor activation. These three phosphorylated proteins then interact with SH2 domain containing signaling proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0290R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0290R-A555
Lokale Artikelnummer::
BOSSBS-0290R-A555
Beschreibung:
The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit (95 kDa) possesses a single transmembrane domain, whereas the alpha subunit (135 kDa) is completely extracellular. The insulin receptor exhibits receptor tyrosine kinase (RTK) activity. RTKs are single pass transmembrane receptors that possess intrinsic cytoplasmic enzymatic activity, catalyzing the transfer of the gamma phosphate of ATP to tyrosine residues in protein substrates. RTKs are essential components of signal transduction pathways that affect cell proliferation, differentiation, migration and metabolism.Included in this large protein family are the insulin receptor and the receptors for growth factors such as epidermal growth factor, fibroblast growth factor and vascular endothelial growth factor. Receptor activation occurs through ligand binding, which facilitates receptor dimerization and autophosphorylation of specific tyrosine residues in the cytoplasmic portion. The interaction of insulin with the alpha subunit of the insulin receptor activates the protein tyrosine kinase of the beta subunit, which then undergoes an autophosphorylation that increases its tyrosine kinase activity. Three adapter proteins, IRS1, IRS2 and Shc, become phosphorylated on tyrosine residues following insulin receptor activation. These three phosphorylated proteins then interact with SH2 domain containing signaling proteins.
VE:
1 * 100 µl
Artikel-Nr:
(200125B)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC200125B
Beschreibung:
Bromkresolgrün, Pulver pH-Indikator
VE:
1 * 25 g
Lieferant:
Thermo Scientific
Beschreibung:
N,N-Diisopropylethylendiamin 97%
Artikel-Nr:
(L09381.06)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
L09381.06
Lokale Artikelnummer::
ALFAL09381.06
Beschreibung:
Methylthymolblau Natriumsalz
VE:
1 * 5 g
Lieferant:
VWR Chemicals
Beschreibung:
Primary stain for Gram staining
Lieferant:
Thermo Scientific
Beschreibung:
Methylenblau Trihydrat 95%, rein
Artikel-Nr:
(LOVI231200)
Lieferant:
Lovibond Tintometer
Hersteller-Artikelnummer::
231200
Lokale Artikelnummer::
LOVI231200
Beschreibung:
A wide range of test discs containing a series of graded glass filters, which have been pre-calibrated to give direct test readings. The unique feature of Lovibond® test discs is that they incorporate coloured glass filters which are colour stable and not affected by UV light or extreme environmental conditions.
VE:
1 * 1 ST
Lieferant:
Alfa Aesar
Beschreibung:
α-Naphtholphthalein
Artikel-Nr:
(BLDPBD1776-10G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD1776-10G
Lokale Artikelnummer::
BLDPBD1776-10G
Beschreibung:
N,N',N''-Tris(p-toluenesulphonyl)diethylenetriamine 95%
VE:
1 * 10 g
Artikel-Nr:
(786-453)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
786-453
Lokale Artikelnummer::
GENO786-453
Beschreibung:
The Phosphatase Assay Kit is designed to measure the activity of phosphatases in biological samples and to screen for agonists and inhibitors of phosphatases. The Phosphatase Assay Kit uses para-nitrophenyl phosphate (pNPP), a chromogenic substrate for most phosphatases, including alkaline phosphatases, acid phosphatases, protein tyrosine phosphatases and serine/threonine phosphatases.
VE:
1 * 1 KIT
Lieferant:
Alfa Aesar
Beschreibung:
Zink(II)acetylacetonat Monohydrat
Lieferant:
Alfa Aesar
Beschreibung:
o-Kresolphthalein
Artikel-Nr:
(01363-100ML-F)
Lieferant:
SIGMA ALDRICH MICROSCOPY
Hersteller-Artikelnummer::
01363-100ML-F
Lokale Artikelnummer::
SIAM01363-100ML-F
Beschreibung:
Methylene blue, Neisser formulation. Well developed granules of volutin (polyphosphate) may be seen in unstained wet preparations as round refractive bodies within the bacterial cytoplasm. With methylene blue they stain metachromatically, a reddish purple color.
VE:
1 * 100 mL
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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