3,4-Dimethoxyphenylborons\\\\u00E4urepinakolester
Artikel-Nr:
(BOSSBS-13248R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13248R-CY7
Lokale Artikelnummer::
BOSSBS-13248R-CY7
Beschreibung:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).
VE:
1 * 100 µl
Artikel-Nr:
(36372-50MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
36372-50MG
Lokale Artikelnummer::
SUPL36372-50MG
Beschreibung:
Profenofos CRM kann auch wie folgt verwendet werden: Auswertung von 250 Pestizidrückständen, die mit der QuEChERS-Methode aus 103 verarbeiteten Fruchtproben unter Verwendung von Hochleistungsflüssigchromatographie-Tandem-Massenspektrometrie (UHPLC-MS/MS) extrahiert wurden. Auf Gaschromatographie-Tandem-Massenspektrometrie (GC-MS/MS) basierende Analyse von 213 Pestizidrückständen in Sojabohnen nach ihrer Extraktion mit dem QuEChERS-Verfahren. Nachweis von 252 Pestiziden, die aus Oberflächenwasserproben durch Festphasenextraktion (SPE) unter Verwendung von Flüssigchromatographie extrahiert wurden Quadrupol-Orbitrap-Tandem-Massenspektrometrie mit hoher Auflösung. Mehrfachrückstandsanalyse von 160 Pestiziden verschiedener Klassen unter Verwendung einer Mischung aus Ethylacetat (EtAC) und n. Hexan zur Extraktion aus Kamillen-, Thymian- und Majoranproben und deren Analyse mittels Gaschromatographie-Tandem-Massenspektrometrie (GC-MS/MS). Gleichzeitige Bestimmung von 34 Pestiziden in verschiedenen Umweltwasserproben mittels dispersiver Flüssig-Flüssig-Mikroextraktion (DLLME) in Kombination mit Gaschromatographie-Massenspektrometrie (GC-MS/MS). Quantifizierung von 40 Insektiziden und Fungiziden verschiedener Klassen in 81 Apfelproben mittels Gas- und Flüssigchromatographie-Massenspektrometrie nach einer QuEChERS-basierten Extraktion.
VE:
1 * 50 mg
Artikel-Nr:
(PRSI27-122)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-122
Lokale Artikelnummer::
PRSI27-122
Beschreibung:
GTF2I is a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon (s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants. This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Four transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-13248R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13248R-A680
Lokale Artikelnummer::
BOSSBS-13248R-A680
Beschreibung:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13248R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13248R-A750
Lokale Artikelnummer::
BOSSBS-13248R-A750
Beschreibung:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13248R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13248R-CY3
Lokale Artikelnummer::
BOSSBS-13248R-CY3
Beschreibung:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13248R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13248R
Lokale Artikelnummer::
BOSSBS-13248R
Beschreibung:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).
VE:
1 * 100 µl
Artikel-Nr:
(PRSI76-672)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-672
Lokale Artikelnummer::
PRSI76-672
Beschreibung:
The OKT8 monoclonal antibody specifically reacts with human CD8alpha molecule, a type I transmembrane glycoprotein of 32 to 34 kDa. CD8 alpha is a member of the Ig superfamily, expressed as a homodimer (CD8 alpha alpha) or as a heterodimer (CD8 alpha beta). CD8+ alpha beta T lymphocytes express both CD8 alpha alpha and CD8 alpha beta, while some T lymphocytes and the natural killer cells express only the homodimers. CD8 binds to MHC class I and influences the development and the activation of T lymphocytes. OKT8, RPA-T8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitoPEor block each other by steric hindrance.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450 nm.
VE:
1 * 100 Tests
Artikel-Nr:
(PRSI76-664)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-664
Lokale Artikelnummer::
PRSI76-664
Beschreibung:
The OKT8 monoclonal antibody specifically reacts with human CD8alpha molecule, a type I transmembrane glycoprotein of 32 to 34 kDa. CD8 alpha is a member of the Ig superfamily, expressed as a homodimer (CD8 alpha alpha) or as a heterodimer (CD8 alpha beta). CD8+ alpha beta T lymphocytes express both CD8 alpha alpha and CD8 alpha beta, while some T lymphocytes and the natural killer cells express only the homodimers. CD8 binds to MHC class I and influences the development and the activation of T lymphocytes. OKT8, RPA-T8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitoPEor block each other by steric hindrance.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450 nm.
VE:
1 * 500 Tests
Artikel-Nr:
(PRSI76-674)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-674
Lokale Artikelnummer::
PRSI76-674
Beschreibung:
The OKT8 monoclonal antibody specifically reacts with human CD8alpha molecule, a type I transmembrane glycoprotein of 32 to 34 kDa. CD8 alpha is a member of the Ig superfamily, expressed as a homodimer (CD8 alpha alpha) or as a heterodimer (CD8 alpha beta). CD8+ alpha beta T lymphocytes express both CD8 alpha alpha and CD8 alpha beta, while some T lymphocytes and the natural killer cells express only the homodimers. CD8 binds to MHC class I and influences the development and the activation of T lymphocytes. OKT8, RPA-T8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitoPEor block each other by steric hindrance.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450 nm.
VE:
1 * 500 Tests
Artikel-Nr:
(PRSI76-670)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-670
Lokale Artikelnummer::
PRSI76-670
Beschreibung:
The OKT8 monoclonal antibody specifically reacts with human CD8alpha molecule, a type I transmembrane glycoprotein of 32 to 34 kDa. CD8 alpha is a member of the Ig superfamily, expressed as a homodimer (CD8 alpha alpha) or as a heterodimer (CD8 alpha beta). CD8+ alpha beta T lymphocytes express both CD8 alpha alpha and CD8 alpha beta, while some T lymphocytes and the natural killer cells express only the homodimers. CD8 binds to MHC class I and influences the development and the activation of T lymphocytes. OKT8, RPA-T8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitoPEor block each other by steric hindrance.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450 nm.
VE:
1 * 100 Tests
Artikel-Nr:
(PRSI76-673)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-673
Lokale Artikelnummer::
PRSI76-673
Beschreibung:
The OKT8 monoclonal antibody specifically reacts with human CD8alpha molecule, a type I transmembrane glycoprotein of 32 to 34 kDa. CD8 alpha is a member of the Ig superfamily, expressed as a homodimer (CD8 alpha alpha) or as a heterodimer (CD8 alpha beta). CD8+ alpha beta T lymphocytes express both CD8 alpha alpha and CD8 alpha beta, while some T lymphocytes and the natural killer cells express only the homodimers. CD8 binds to MHC class I and influences the development and the activation of T lymphocytes. OKT8, RPA-T8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitoPEor block each other by steric hindrance.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450 nm.
VE:
1 * 25 Tests
Artikel-Nr:
(PRSI76-665)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-665
Lokale Artikelnummer::
PRSI76-665
Beschreibung:
The OKT8 monoclonal antibody specifically reacts with human CD8alpha molecule, a type I transmembrane glycoprotein of 32 to 34 kDa. CD8 alpha is a member of the Ig superfamily, expressed as a homodimer (CD8 alpha alpha) or as a heterodimer (CD8 alpha beta). CD8+ alpha beta T lymphocytes express both CD8 alpha alpha and CD8 alpha beta, while some T lymphocytes and the natural killer cells express only the homodimers. CD8 binds to MHC class I and influences the development and the activation of T lymphocytes. OKT8, RPA-T8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitoPEor block each other by steric hindrance.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450 nm.
VE:
1 * 100 Tests
Artikel-Nr:
(PRSI76-671)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-671
Lokale Artikelnummer::
PRSI76-671
Beschreibung:
The OKT8 monoclonal antibody specifically reacts with human CD8alpha molecule, a type I transmembrane glycoprotein of 32 to 34 kDa. CD8 alpha is a member of the Ig superfamily, expressed as a homodimer (CD8 alpha alpha) or as a heterodimer (CD8 alpha beta). CD8+ alpha beta T lymphocytes express both CD8 alpha alpha and CD8 alpha beta, while some T lymphocytes and the natural killer cells express only the homodimers. CD8 binds to MHC class I and influences the development and the activation of T lymphocytes. OKT8, RPA-T8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitoPEor block each other by steric hindrance.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450 nm.
VE:
1 * 25 Tests
Artikel-Nr:
(BOSSBS-11236R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11236R-A680
Lokale Artikelnummer::
BOSSBS-11236R-A680
Beschreibung:
During vertebrate embryogenesis, a left right axis is established. Secreted growth factors of the TGF beta family, including gene products derived from nodal, lefty 1 and lefty 2, play crucial roles in establishing left right asymmetries. TGF beta (Transforming growth factor beta) is a pleiotropic cytokine that regulates growth and differentiation of diverse types of cells. TGF beta actions are directed by ligand induced activation of TGF beta receptors. Complexes formed move into the nucleus, where they act as components of a transcriptional complex. Lefty, a novel member of the TGF beta superfamily, inhibits TGF beta Signalling. Lefty acts to inhibit phosphorylation of Smad2 following activation of the TGF beta receptor. Lefty also inhibits events downstream from R Smad phosphorylation. Lefty provides a repressed state of TGF beta responsive genes. The Lefty family is comprised of Lefty 1 and Lefty 2 in mouse, and Lefty A and Lefty B in humans. Members of the TGF beta superfamily require processing for their activation. Cleavage is therefore an essential step for Lefty activation. Lefty is synthesised as a large inactive precursor (41 KDa) that must be endoproteolytically processed to release the bioactive polypeptide (28 kDa and 34 kDa forms). The 28kDa form induces MAPK activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11236R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11236R-CY7
Lokale Artikelnummer::
BOSSBS-11236R-CY7
Beschreibung:
During vertebrate embryogenesis, a left right axis is established. Secreted growth factors of the TGF beta family, including gene products derived from nodal, lefty 1 and lefty 2, play crucial roles in establishing left right asymmetries. TGF beta (Transforming growth factor beta) is a pleiotropic cytokine that regulates growth and differentiation of diverse types of cells. TGF beta actions are directed by ligand induced activation of TGF beta receptors. Complexes formed move into the nucleus, where they act as components of a transcriptional complex. Lefty, a novel member of the TGF beta superfamily, inhibits TGF beta signaling. Lefty acts to inhibit phosphorylation of Smad2 following activation of the TGF beta receptor. Lefty also inhibits events downstream from R Smad phosphorylation. Lefty provides a repressed state of TGF beta responsive genes. The Lefty family is comprised of Lefty 1 and Lefty 2 in mouse, and Lefty A and Lefty B in humans. Members of the TGF beta superfamily require processing for their activation. Cleavage is therefore an essential step for Lefty activation. Lefty is synthesized as a large inactive precursor (41 Kda) that must be endoproteolytically processed to release the bioactive polypeptide (28 kDa and 34 kDa forms). The 28kDa form induces MAPK activity.
VE:
1 * 100 µl
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