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Tetramethylthiurammonosulfid
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Tetramethylthiurammonosulfid
Artikel-Nr:
(BOSSBS-5105R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5105R-A750
Lokale Artikelnummer::
BOSSBS-5105R-A750
Beschreibung:
PRE7 is a subunit of the Yeast proteasome. The yeast proteasome seems to be composed of 14 different subunits which form a highly ordered ring-shaped structure. The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4208R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4208R-A488
Lokale Artikelnummer::
BOSSBS-4208R-A488
Beschreibung:
Cullin 1 may be involved in the degradation of positive cell cycle regulators (for example G1 cyclins in yeast). Human cullin 1 forms a complex with Skp1 and the F box protein Skp2, which is thought to play a role in the ubiquitination of G1 regulatory proteins, as its homolog does in yeast.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6647R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6647R-A555
Lokale Artikelnummer::
BOSSBS-6647R-A555
Beschreibung:
There are eight COG proteins (COG1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that COG1 is required for steps in the normal medial and trans Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0417R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0417R-CY5
Lokale Artikelnummer::
BOSSBS-0417R-CY5
Beschreibung:
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6647R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6647R-CY5.5
Lokale Artikelnummer::
BOSSBS-6647R-CY5.5
Beschreibung:
There are eight COG proteins (COG1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that COG1 is required for steps in the normal medial and trans Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0183R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0183R-A750
Lokale Artikelnummer::
BOSSBS-0183R-A750
Beschreibung:
Estrogen and progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands. The interaction of hormone-bound estrogen receptors with estrogen responsive elements(EREs) alters transcription of ERE-containing genes. The carboxy terminal region of the estrgen receptor contains the ligand binding domain, the amino terminus serves as the transactivation domain, and the DNA binding domain is centrally located. Two forms of estrogen receptor have been identified, ER alpha and ER beta. ER alpha and ER beta have been shown to be differentially activated by various ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-Aand hPR-B), which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1879R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1879R-A350
Lokale Artikelnummer::
BOSSBS-1879R-A350
Beschreibung:
Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta-galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases. Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12). Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0183R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0183R-A680
Lokale Artikelnummer::
BOSSBS-0183R-A680
Beschreibung:
Estrogen and progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands. The interaction of hormone-bound estrogen receptors with estrogen responsive elements(EREs) alters transcription of ERE-containing genes. The carboxy terminal region of the estrgen receptor contains the ligand binding domain, the amino terminus serves as the transactivation domain, and the DNA binding domain is centrally located. Two forms of estrogen receptor have been identified, ER alpha and ER beta. ER alpha and ER beta have been shown to be differentially activated by various ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-Aand hPR-B), which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11067R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11067R-A555
Lokale Artikelnummer::
BOSSBS-11067R-A555
Beschreibung:
Beta-tectorin is a 329 amino acid secreted protein that contains one zona pellucida (ZP) domain. While it may form homomeric filaments after self-association, Beta-tectorin may also form heteromeric filaments when it associates with ?tectorin. The presence of a hydrophobic C-terminus preceded by a potential cleavage site strongly suggests that tectorins are synthesized as glycosylphosphatidylinositol-linked, membrane-bound precursors. Tectorins are targeted to the apical surface of the inner ear epithelia and proteolytically released into the extracellular compartment. Beta-tectorin is one of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7526R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7526R-CY3
Lokale Artikelnummer::
BOSSBS-7526R-CY3
Beschreibung:
BTG1 belongs to the BTG family of proteins.FUNCTION: Anti-proliferative protein. Its expression is associated with the early G1 phase of the cell cycle. A chromosomal aberration involving BTG1 may be a cause of a form of B cell chronic lymphocytic leukemia; translocation t(8;12)(q24;q22) with MYC.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15522R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15522R-CY7
Lokale Artikelnummer::
BOSSBS-15522R-CY7
Beschreibung:
IFNAR1 is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
VE:
1 * 100 µl
Artikel-Nr:
(50007.)
Lieferant:
Biotium
Hersteller-Artikelnummer::
50007
Lokale Artikelnummer::
BTIU50007
Beschreibung:
Dimethyl BAPTA AM ester is a membrane permeable form of Dimethyl BAPTA that can be loaded into cells by incubation. Dimethyl BAPTA AM ester itself does not bind calcium, but once inside the cell is converted into Dimethyl BAPTA by cytoplasmic esterases.
VE:
1 * 25 mg
Artikel-Nr:
(BSENR-1686-500)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1686-500
Lokale Artikelnummer::
BSENR-1686-500
Beschreibung:
Nicastrin, a type 1 membrane glycoprotein, is an essential component of the gamma secretase complex which is critical for the cleavage of the amyloid precursor protein and other membrane proteins. Nicastrin is widely expressed in different tissue types. This antibody detects all processed forms of Nicastrin.
VE:
1 * 500 µG
Artikel-Nr:
(BOSSBS-11816R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11816R-CY3
Lokale Artikelnummer::
BOSSBS-11816R-CY3
Beschreibung:
Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor called Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3) and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. Cerebellin and its metabolite, des-Ser(1)Cer, are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other’s degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1. Decreased concentrations of Cerebellin have been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome, suggesting a role for Cerebellin in the pathology of these diseases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11815R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11815R-FITC
Lokale Artikelnummer::
BOSSBS-11815R-FITC
Beschreibung:
Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3), and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. CER and it metabolite des-Ser1-cerebellin are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other’s degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1. Decreased concentrations of CER has been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome, suggesting a role for CER in the pathology of these diseases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8604R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8604R-CY5.5
Lokale Artikelnummer::
BOSSBS-8604R-CY5.5
Beschreibung:
Major histocompatibility complex (MHC) molecules form an integral part of the immune response system. They are cell-surface receptors that bind peptides and present them to T lymphocytes. Human leukocyte antigens (HLAs) are polymorphic members of the MHC family that are specifically involved in the presentation of antigens to the T cell receptor. There are two classes of HLA antigens: class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). Class I molecules are expressed in nearly all cells and play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes. HLA-B encodes a membrane anchored heavy chain which hetero-dimerizes with a light chain (∫-2-Microglobulin) to form MHC-I. Polymorphisms yield hundreds of HLA-B alleles. The HLA-B27 allele appears with increased frequency in uveitis patients.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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