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3,5-Dichloro-4-fluorophenol
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3,5-Dichloro-4-fluorophenol
Artikel-Nr:
(PRSI28-255)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-255
Lokale Artikelnummer::
PRSI28-255
Beschreibung:
FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein.This reference sequence was derived from AF161462.1 and ESTs; validated by multiple replicate ESTs and human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein. Two transcript variants have been found for this gene, and they are both predicted to encode the same protein.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-485)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-485
Lokale Artikelnummer::
PRSI91-485
Beschreibung:
Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition, Serpin A5 additionally inhibits a variety of serine protease including thrombin, factor Xa, several kallekreins and acrosin. It plays a critical role in the processes of blood of blood coagulation and fertilization. Serpin A5 also inhibits urinary plasminogen activator (uPA), a mediator of tumor cell invasion, and regulates tumor growth and metastasis by inhibiting angiogenesis. Furthermore, recent studies have identified PCI as a potent and direct inhibitor of activated HGFA (hepatocyte growth factor activator), suggesting a novel function in the regulation of tissue repair and regeneration. Similar to Serpins C1 and D1, the thrombin inhibitory activity of serpinA5 is enhanced by heparin.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-502)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-502
Lokale Artikelnummer::
PRSI90-502
Beschreibung:
Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. IL-12 is produced by macrophages and B lymphocytes and has been shown to have multiple effects on T cells and Natural Killer (NK) cells. Some of these IL-12 activities include the induction of IFN-gamma and TNF in resting and activated T and NK cells; the enhancement of cytotoxic activity of resting NK and T cells, the stimulation of resting T cell proliferation in the presence of a comitogen; and the enhancement of NK cell proliferation. Current evidence indicates that IL-12 is a key mediator of cellular immunity and induces the differentiation of Th1 cells from precursor T helper cells. Based on its activities, it has been suggested that IL-12 may have therapeutic potential as a vaccine adjuvant that promotes cellular immunity and as an antitumour and anti viral agent.
VE:
1 * 25 µG
Artikel-Nr:
(PRSI91-488)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-488
Lokale Artikelnummer::
PRSI91-488
Beschreibung:
Serpin F1 is a secreted glycoprotein that belongs to the noninhibitory serpin. It has an alpha/beta core serine-protease inhibitor domain, three major beta-sheets, and ten alpha-helices. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins. Serpin F1 is a new promising approach for the treatment of osteosarcoma and has been described as a natural angiogenesis inhibitor with neurotrophic and immune-modulation properties. The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Levels of the natural ocular anti-angiogenic factor SentrinF1 (PEDF) is associated with proliferative retinopathy.
VE:
1 * 50 µG
Lieferant:
FRISTADS KANSAS
Beschreibung:
Diese Latzhosen mit elastischen Hosenträgern sind aus verschiedenen Geweben gefertigt. Die wasserabweisenden fluoreszierenden Materialien bestehen aus 80% Polyester und 20% Baumwolle. Die anderen Teile bestehen aus 65% Polyester und 35% Baumwolle mit leicht gebürsteter Rückseite. Die Verstärkungen bestehen aus 100% Polyamid.
Artikel-Nr:
(PIER21218)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
21218
Lokale Artikelnummer::
PIER21218
Beschreibung:
Thermo Scientific EZ-Link PFP-biotin is a pentafluorophenyl-ester biotinylation reagent that has similar properties to NHS-biotin but is more reactive and will target both primary and secondary amines for biotinylation.
VE:
1 * 50 mg
Artikel-Nr:
(J62143.AP)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
J62143.AP
Lokale Artikelnummer::
ALFAJ62143.AP
Beschreibung:
Excellent colorimetric substrate for detection of horseradish peroxidase labelled probes and is used with peroxidase and peroxidase coupled systems, particularly in ELISA techniques, blue result.
VE:
1 * 500 mL
Artikel-Nr:
(PRSI92-722)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-722
Lokale Artikelnummer::
PRSI92-722
Beschreibung:
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA encodes 223 amino acids (aa) including a 35 aa signal sequence, a 126 aa extracellular domain (ECD) with one Ig-like V-type domain, a 21 aa transmembrane (TM) sequence, and a 41 aa cytoplasmic sequence. It is widely expressed with highest levels in lymphoid tissues. CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.
VE:
1 * 50 µG
Artikel-Nr:
(SERA25834.03)
Lieferant:
Serva
Hersteller-Artikelnummer::
25834.03
Lokale Artikelnummer::
SERA25834.03
Beschreibung:
trans-4-Hydroxy-L(-)-prolin
VE:
1 * 100 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
Portwest Clothing
Beschreibung:
The PW3 Holster Work Shorts are a great addition to the PW3 range, combining function and style. An impressive range of multi-functional pockets including detachable holster pockets, ID pocket, rule pocket and an easy access thigh pocket provide ample secure storage. Premium features such as hammer loop, crotch gusset and reinforced panels for extra durability. The ideal choice for warmer weather.
Lieferant:
Portwest Clothing
Beschreibung:
The holster work shorts are a great addition to the PW3 range, combining function and style and impressive range of multifunctional pockets including detachable holster pockets, ID pocket, rule pocket and an easy access thigh pocket provide ample secure storage.
Lieferant:
BACHEM BIOCHEMICA
Beschreibung:
trans-4-Hydroxy-L(-)-prolin
Artikel-Nr:
(J61325.AP)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
J61325.AP
Lokale Artikelnummer::
ALFAJ61325.AP
Beschreibung:
Excellent colorimetric substrate for detection of horseradish peroxidase labelled probes and is used with peroxidase and peroxidase coupled systems, particularly in ELISA techniques, blue result.
VE:
1 * 500 mL
Artikel-Nr:
(PRSI90-503)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-503
Lokale Artikelnummer::
PRSI90-503
Beschreibung:
Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. IL-12 is produced by macrophages and B lymphocytes and has been shown to have multiple effects on T cells and Natural Killer (NK) cells. Some of these IL-12 activities include the induction of IFN-gamma and TNF in resting and activated T and NK cells; the enhancement of cytotoxic activity of resting NK and T cells, the stimulation of resting T cell proliferation in the presence of a comitogen; and the enhancement of NK cell proliferation. Current evidence indicates that IL-12 is a key mediator of cellular immunity and induces the differentiation of Th1 cells from precursor T helper cells. Based on its activities, it has been suggested that IL-12 may have therapeutic potential as a vaccine adjuvant that promotes cellular immunity and as an antitumour and anti viral agent.
VE:
1 * 25 µG
Artikel-Nr:
(PRSI33-392)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-392
Lokale Artikelnummer::
PRSI33-392
Beschreibung:
Recognises a DQ antigen, which is a dimer of 60 kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(UPTIUP070440)
Lieferant:
Uptima
Hersteller-Artikelnummer::
UP070440
Lokale Artikelnummer::
UPTIUP070440
Beschreibung:
ortho-Borsäure
VE:
1 * 1 kg
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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