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3,5-Dichlorphenylboronsäurepinakolester
Artikel-Nr:
(BOSSBS-9067R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-CY3
Lokale Artikelnummer::
BOSSBS-9067R-CY3
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-A555
Lokale Artikelnummer::
BOSSBS-9067R-A555
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-A750
Lokale Artikelnummer::
BOSSBS-9067R-A750
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle sise <i>in vivo</i>. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(USBI123359)
Lieferant:
US Biological
Hersteller-Artikelnummer::
123359
Lokale Artikelnummer::
USBI123359
Beschreibung:
Anti-ANXA3 Mouse Monoclonal Antibody [clone: 4F1]
VE:
1 * 100 µG
Artikel-Nr:
(BREU76520)
Lieferant:
BREUKHOVEN
Hersteller-Artikelnummer::
76520
Lokale Artikelnummer::
BREU76520
Beschreibung:
The BMS Trekker is a high quality handheld microscope that enhances objects up to 35 times.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-9047R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9047R-FITC
Lokale Artikelnummer::
BOSSBS-9047R-FITC
Beschreibung:
Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
VE:
1 * 100 µl
Artikel-Nr:
(HACH2584335)
Lieferant:
Hach
Hersteller-Artikelnummer::
2584335
Lokale Artikelnummer::
HACH2584335
Beschreibung:
PP, translucent.
VE:
1 * 1 ST
Artikel-Nr:
(USBI037744-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
037744-BIOTIN
Lokale Artikelnummer::
USBI037744-BIOTIN
Beschreibung:
Anti-LGALS3 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(ABNOMAB2192)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB2192
Lokale Artikelnummer::
ABNOMAB2192
Beschreibung:
Hamster monoclonal antibody raised against recombinant Bcl3.
VE:
1 * 100 µG
Lieferant:
EPPENDORF
Beschreibung:
Stahlhülse, für Rotor, F-35-30-17, 15 ml, Für: Eppendorf 5702 / 5702 R / 5702 RH, Tisch-Zentrifuge
Artikel-Nr:
(732-0025)
Lieferant:
Harvard Apparatus
Hersteller-Artikelnummer::
45-0130
Lokale Artikelnummer::
BTXI45-0130
Beschreibung:
The Petri Pulser™ electrode is a reusable electroporation applicator designed to fit into each single well of a 6-well plate or an individual 35 mm diameter Petri dish. It is suitable for the electroporation of adherent cells in situ or as an alternative to cuvette electroporation for larger cell suspensions volumes.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-9067R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-HRP
Lokale Artikelnummer::
BOSSBS-9067R-HRP
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BRND144640)
Lieferant:
Brand
Hersteller-Artikelnummer::
144640
Lokale Artikelnummer::
BRND144640
Beschreibung:
DURAN®.Hohl, mit Abtropfspitze und Sechskantgriffscheibe.
VE:
1 * 1 ST
Artikel-Nr:
(233-0003)
Lieferant:
MURRAY S
Hersteller-Artikelnummer::
D021/G2
Lokale Artikelnummer::
MURRD021/G2
Beschreibung:
These scalpels with light pattern are completely made from stainless steel.
VE:
1 * 1 ST
Lieferant:
VICI JOUR RESEARCH
Beschreibung:
Mit Flachfilterelement, das eine Entnahme der maximalen Menge an mobiler Phase aus dem Reservoir ermöglicht, ohne dass Luft in das System gelangt.
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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