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3,5-Dichlorphenylboronsäurepinakolester
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3,5-Dichlorphenylboronsäurepinakolester
Artikel-Nr:
(BTIUBNUM1070-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM1070-50
Lokale Artikelnummer::
BTIUBNUM1070-50
Beschreibung:
This antibody recognizes a protein of 35 kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This MAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis.Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L( )-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher's Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts.
VE:
1 * 50 µl
Artikel-Nr:
(FLUO022144-1G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
022144-1G
Lokale Artikelnummer::
FLUO022144-1G
Beschreibung:
trans-2-(4-Butylphenyl)cyclopentanol
VE:
1 * 1 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(HECH43599010)
Lieferant:
GLASWARENFABRIK KARL HECHT
Hersteller-Artikelnummer::
43599010
Lokale Artikelnummer::
HECH43599010
Beschreibung:
This freezer thermometer made of plastic is supplied with holder and factory certificate. Officially verified.
VE:
1 * 1 ST
Lieferant:
Sigma-Aldrich
Beschreibung:
Lithiumbromid, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-9067R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-A488
Lokale Artikelnummer::
BOSSBS-9067R-A488
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R
Lokale Artikelnummer::
BOSSBS-9067R
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(USBI123359)
Lieferant:
US Biological
Hersteller-Artikelnummer::
123359
Lokale Artikelnummer::
USBI123359
Beschreibung:
Anti-ANXA3 Mouse Monoclonal Antibody [clone: 4F1]
VE:
1 * 100 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
Triphenylphosphin, Sigma-Aldrich®
Lieferant:
Hettich
Beschreibung:
Festwinkelrotor 1556 A, 35°, 6×94 ml, 9000 min<sup>-1</sup>, 10595 ×g: Dieser Rotor kann/darf nicht von alten Universal 320/320R Zentrifugen eingesetzt werden. Setzen Sie sich bitte vor der Bestellung mit Ihrem Avantor-Verkaufsteam in Verbindung., Für: Hettich
Artikel-Nr:
(COWI010.114)
Lieferant:
COWIE
Hersteller-Artikelnummer::
010.114
Lokale Artikelnummer::
COWI010.114
Beschreibung:
PTFE. Stopper with flat head fit standard ground glass joints.
VE:
1 * 1 ST
Artikel-Nr:
(SIAL130273-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
130273-5G
Lokale Artikelnummer::
SIAL130273-5G
Beschreibung:
8-Nitrochinolin, Sigma-Aldrich®
VE:
1 * 5 g
Artikel-Nr:
(212-3232)
Lieferant:
SEMADENI
Hersteller-Artikelnummer::
1696
Lokale Artikelnummer::
SEMA1696
Beschreibung:
PS, clear, with white push-in stopper.
VE:
1 * 100 ST
Lieferant:
Alfa Aesar
Beschreibung:
Lithiumbromid, wasserfrei ≥99%
Artikel-Nr:
(BOSSBS-9047R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9047R-A680
Lokale Artikelnummer::
BOSSBS-9047R-A680
Beschreibung:
Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarisation and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid <i>in vitro</i>. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-CY5.5
Lokale Artikelnummer::
BOSSBS-9067R-CY5.5
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-A647
Lokale Artikelnummer::
BOSSBS-9067R-A647
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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