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(2-Hydroxylpropyl)-β-cyclodextrin
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(2-Hydroxylpropyl)-β-cyclodextrin
Artikel-Nr:
(BOSSBS-11260R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11260R-A750
Lokale Artikelnummer::
BOSSBS-11260R-A750
Beschreibung:
Members of the transforming growth factor-beta (TGF-Beta) superfamily play critical roles in controlling cell growth and differentiation. Effects of TGF-Beta family ligands are mediated by Smad proteins. The Smad nuclear interacting protein (SNIP1) contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. SNIP1 potently inhibits the activity of NF-kappa B, which binds the C/H1 domain of CBP/p300, by competing for the binding site. SNIP1 is also thought to induce expression of Cyclin D1 to promote cellular proliferation. SNIP1 is ubiquitously expressed with high expression in heart and skeletal muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9919R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9919R-A680
Lokale Artikelnummer::
BOSSBS-9919R-A680
Beschreibung:
Transcobalamin I (TCI) and Transcobalamin II (TCII) are secreted proteins belonging to the eukaryotic cobalamin transport proteins family and also to the vitamin B12-binding protein family. The genes encoding these proteins map to chromosome 11q11-q12 and 22q12.2, respectively. Transcobalamin I is a constituent of secondary granules in neutrophils, while Transcobalamin II binds cobalamin and mediates its transport into cells. These plasma proteins are expressed in various tissues and secretions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10516R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10516R-CY5
Lokale Artikelnummer::
BOSSBS-10516R-CY5
Beschreibung:
This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11365R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11365R-CY3
Lokale Artikelnummer::
BOSSBS-11365R-CY3
Beschreibung:
In all vertebrates, SV2 proteins are abundant, hydrophobic, membrane glycoproteins that are expressed as two major isoforms, SV2A and SV2B, and one minor isoform, SV2C. SV2 proteins are differentially expressed in the brain and are present on all synaptic vesicles, independent of transmitter type. SV2A is abundantly expressed in the subcortex, specifically in the synaptic vesicles of all presynaptic nerve terminals, and also in most neuroendocrine secretory granules. SV2B displays a more restricted pattern of expression in that it is only present on a small subset of synapses in the hippocampus and cortex. SV2A and SV2B are funtionally redundant and are required for maintaining normal brain function in vertebrates. SV2A and SV2B mediate synaptic transmission by regulating cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12032R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12032R-CY7
Lokale Artikelnummer::
BOSSBS-12032R-CY7
Beschreibung:
Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13002R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13002R-A350
Lokale Artikelnummer::
BOSSBS-13002R-A350
Beschreibung:
Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12161R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12161R-A350
Lokale Artikelnummer::
BOSSBS-12161R-A350
Beschreibung:
CAPS1 is a 189 amino acid cytoplasmic protein that contains four EF-hand domains, which serve as calcium-binding sites, and was first identified in canine thyroid. Interestingly, CAPS1 is much less abundant in humans than in canines. Synthesis and phosphorylation of CAPS1 is upregulated by cAMP-agonists in thyrocytes. CAPS1 likely functions in the regulation of ionic transport and may be involved in cross-signaling between cAMP and Ca(+2)-phophatidylinositol cascades. In addition to thyriod, CAPS1 is expressed in brain, salivary glands and lung. Expression of CAPS1 is increased in endometrial cancer and prognosis seems to be dependent on the level of CAPS1 expression, indicating that CAPS1 may be an appropriate prognostic marker for patient survival.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0073R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0073R-CY5
Lokale Artikelnummer::
BOSSBS-0073R-CY5
Beschreibung:
Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8185R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8185R
Lokale Artikelnummer::
BOSSBS-8185R
Beschreibung:
May regulate transport of alpha4-beta2 neuronal acetylcholine receptor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9209R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9209R
Lokale Artikelnummer::
BOSSBS-9209R
Beschreibung:
ZPI, also known as SERPINA10 (serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10) or PZI, is a 444 amino acid secreted protein that functions as a Protein Z-dependent protease inhibitor. Expressed by the liver, ZPI is secreted into the plasma where, in the presence of calcium, Protein Z and phospholipids, it inhibits the activated pro-coagulation factors X and XI (Factor X and Factor XI). This inhibition helps properly regulate intravenous blood clotting. ZPI, a member of the serpin protein family, contains five potential N-linked glycosylation sites and a tyrosine at position 387 which, when disrupted, renders ZPI inactive. Defects in the gene encoding ZPI may increase susceptibility to venous thrombosis, the formation of blood clots within a vein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11702R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11702R-A680
Lokale Artikelnummer::
BOSSBS-11702R-A680
Beschreibung:
The endophilins comprise a family of three SH3 domain-containing proteins designated Endophilin I, II and III, or alternatively known as SH3P4, SH3P8 and SH3P13, respectively. These proteins associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the endophilins are consistent with their cellular functions at the neuronal synapse, as Endophilin I is ex- pressed only in the brain. Both Endophilin II and Endophilin III are detected in a variety of tissues. Endophilin I is also implicated in modulating G protein-coupled receptor Signalling by functioning as an adapter protein and directing 1 adrenergic receptors to the endocytic machinery.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6546R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6546R-A750
Lokale Artikelnummer::
BOSSBS-6546R-A750
Beschreibung:
The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15507R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15507R-A555
Lokale Artikelnummer::
BOSSBS-15507R-A555
Beschreibung:
Catalyses the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4609R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4609R-A750
Lokale Artikelnummer::
BOSSBS-4609R-A750
Beschreibung:
Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15252R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15252R-A680
Lokale Artikelnummer::
BOSSBS-15252R-A680
Beschreibung:
Making up nearly 6% of the human genome, chromosome 6 contains around 1200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf70 gene product has been provisionally designated C6orf70 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7738R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7738R-A750
Lokale Artikelnummer::
BOSSBS-7738R-A750
Beschreibung:
Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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