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3,5-Diisopropylpyrazole
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3,5-Diisopropylpyrazole
Artikel-Nr:
(BOSSBS-9067R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-CY5
Lokale Artikelnummer::
BOSSBS-9067R-CY5
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-FITC
Lokale Artikelnummer::
BOSSBS-9067R-FITC
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-A350
Lokale Artikelnummer::
BOSSBS-9067R-A350
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(CHMPSILS03775.)
Lieferant:
CHEMPUR
Hersteller-Artikelnummer::
SILS03775.
Lokale Artikelnummer::
CHMPSILS03775.
Beschreibung:
Chlordimethylsilan
VE:
1 * 1 ST
Artikel-Nr:
(1029013.)
Lieferant:
USP
Hersteller-Artikelnummer::
1029013
Lokale Artikelnummer::
USPH1029013
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 25 mg
Artikel-Nr:
(1269200.)
Lieferant:
USP
Hersteller-Artikelnummer::
1269200
Lokale Artikelnummer::
USPH1269200
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 125 mg
Artikel-Nr:
(215-1744)
Lieferant:
Brand
Hersteller-Artikelnummer::
130538
Lokale Artikelnummer::
BRND130538
Beschreibung:
PTFE, starkwandig.
VE:
1 * 1 ST
Lieferant:
COMBI-BLOCKS
Beschreibung:
2-(Methylthio)-5-nitrobenzonitril
Lieferant:
Brand
Beschreibung:
LDPE.
Lieferant:
Sigma-Aldrich
Beschreibung:
2-Bromterephthalsäure, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
2,2-Dimethylpentan, Sigma-Aldrich®
Artikel-Nr:
(SIALD106003-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
D106003-5G
Lokale Artikelnummer::
SIALD106003-5G
Beschreibung:
9,10-Dihydrophenanthren, Sigma-Aldrich®
VE:
1 * 5 g
Lieferant:
Restek
Beschreibung:
These liners can be used with Agilent GCs.
Artikel-Nr:
(ENAMEN300-25341.5G)
Lieferant:
SIA ENAMINE
Hersteller-Artikelnummer::
EN300-25341.5G
Lokale Artikelnummer::
ENAMEN300-25341.5G
Beschreibung:
3-(Brommethyl)-4-fluorbenzonitril
VE:
1 * 5 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(662-8421)
Lieferant:
CHEMPUR
Hersteller-Artikelnummer::
EI01/2
Lokale Artikelnummer::
CHMPEI01/2
Beschreibung:
This design consists of of a slit gauze cylinder containing a concentrically positioned wire spiral.
VE:
1 * 1 ST
Artikel-Nr:
(SIALP53608-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
P53608-25G
Lokale Artikelnummer::
SIALP53608-25G
Beschreibung:
2-Propylphenol, Sigma-Aldrich®
VE:
1 * 25 g
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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