Methyl+2-chloro-6-(trifluoromethyl)isonicotinate
Artikel-Nr:
(BOSSBS-11841R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11841R-CY7
Lokale Artikelnummer::
BOSSBS-11841R-CY7
Beschreibung:
TOCA-1 is a 605 amino acid protein that localizes to the cytoplasm and the cytoskeleton, as well as to cytoplasmic vesicles and the cell membrane, and contains one FCH domain, one REM repeat and one SH3 domain. Existing as multiple alternatively spliced isoforms, TOCA-1 interacts with CDC42 and is required for the coordination of membrane tubulation with Actin cytoskeletal reorganization during endocytosis. Additionally, TOCA-1 is involved in membrane invagination, tubule formation and Actin polymerization. The gene encoding TOCA-1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4820R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4820R-CY3
Lokale Artikelnummer::
BOSSBS-4820R-CY3
Beschreibung:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
VE:
1 * 100 µl
Lieferant:
BLD PHARMATECH GMBH
Beschreibung:
(4-Methoxyphenyl)aceton 98%
Artikel-Nr:
(BOSSBS-13339R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13339R
Lokale Artikelnummer::
BOSSBS-13339R
Beschreibung:
GFM2 is a mitochondrial translation elongation factor. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR27582-100G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR27582-100G
Lokale Artikelnummer::
APOSOR27582-100G
Beschreibung:
2,6-Dimethyl-4-pyron
VE:
1 * 100 g
Artikel-Nr:
(BOSSBS-11726R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11726R-CY7
Lokale Artikelnummer::
BOSSBS-11726R-CY7
Beschreibung:
Hexosaminidase A (HEXA), also designated beta-Hexosaminidase A, is a trimer composed of one å chain, one ∫-A chain and one ∫-B chain and is found in the lysosomes of cells. HEXA, along with the cofactor CM2 activator protein, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues. A mutation in the å subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), also known as GM2-gangliosidosis type I. TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides. The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11726R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11726R-A555
Lokale Artikelnummer::
BOSSBS-11726R-A555
Beschreibung:
Hexosaminidase A (HEXA), also designated beta-Hexosaminidase A, is a trimer composed of one å chain, one ∫-A chain and one ∫-B chain and is found in the lysosomes of cells. HEXA, along with the cofactor CM2 activator protein, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues. A mutation in the å subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), also known as GM2-gangliosidosis type I. TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides. The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13084R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13084R-FITC
Lokale Artikelnummer::
BOSSBS-13084R-FITC
Beschreibung:
EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain, one PH domain and one DH domain. Expressed at high levels in brain and present at lower levels in lung tissue, EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse. EPHEXIN is subject to Src-dependent phosphorylation, an event that increases the GEF activity of EPHEXIN toward Rho A. Human EPHEXIN, which exists as multiple alternatively spliced isoforms, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11458R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11458R-CY7
Lokale Artikelnummer::
BOSSBS-11458R-CY7
Beschreibung:
EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain, one PH domain and one DH domain. Expressed at high levels in brain and present at lower levels in lung tissue, EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse. EPHEXIN is subject to Src-dependent phosphorylation, an event that increases the GEF activity of EPHEXIN toward Rho A. Human EPHEXIN, which exists as multiple alternatively spliced isoforms, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11726R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11726R-A647
Lokale Artikelnummer::
BOSSBS-11726R-A647
Beschreibung:
Hexosaminidase A (HEXA), also designated beta-Hexosaminidase A, is a trimer composed of one å chain, one ∫-A chain and one ∫-B chain and is found in the lysosomes of cells. HEXA, along with the cofactor CM2 activator protein, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues. A mutation in the å subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), also known as GM2-gangliosidosis type I. TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides. The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11458R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11458R
Lokale Artikelnummer::
BOSSBS-11458R
Beschreibung:
EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain, one PH domain and one DH domain. Expressed at high levels in brain and present at lower levels in lung tissue, EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse. EPHEXIN is subject to Src-dependent phosphorylation, an event that increases the GEF activity of EPHEXIN toward Rho A. Human EPHEXIN, which exists as multiple alternatively spliced isoforms, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
6-Chlor-2-hydroxypyridin ≥98%
Lieferant:
EBRO
Beschreibung:
The SL3101 set by ebro, featuring five EBI 12-T471 and one EBI 12-TP453 loggers in silicone protection boxes, is ideal for validating large sterilisers and autoclaves in demanding environments.
Artikel-Nr:
(BOSSBS-12925R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12925R-A680
Lokale Artikelnummer::
BOSSBS-12925R-A680
Beschreibung:
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
4'-Ethoxyacetophenon ≥98%
Artikel-Nr:
(BOSSBS-0522R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0522R-A750
Lokale Artikelnummer::
BOSSBS-0522R-A750
Beschreibung:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
VE:
1 * 100 µl
Preis auf Anfrage
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