3,5-Dioxocyclohexanecarboxylic+acid
Lieferant:
FLUOROCHEM
Beschreibung:
6-(Trifluormethyl)nicotinamid
Artikel-Nr:
(SAMPA625-320)
Lieferant:
Sampling Systems
Hersteller-Artikelnummer::
A625-320
Lokale Artikelnummer::
SAMPA625-320
Beschreibung:
Versatile spoon and spatula for sampling powder and liquid products.
VE:
1 * 1 ST
Lieferant:
Sigma-Aldrich
Beschreibung:
2,6-Bis(hydroxymethyl)-p-kresol, Sigma-Aldrich®
Lieferant:
GLASWARENFABRIK KARL HECHT
Beschreibung:
Aus Borosilikatglas hergestellt.
Artikel-Nr:
(FLUO022741-1G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
022741-1G
Lokale Artikelnummer::
FLUO022741-1G
Beschreibung:
4-Chlor-3',5'-dimethyl-4'-methoxybenzophenon
VE:
1 * 1 g
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Artikel-Nr:
(PRSI90-535)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-535
Lokale Artikelnummer::
PRSI90-535
Beschreibung:
Interleukin-35 (IL-35) is a novel IL-12 family cytokine produced by regulatory T cells (Treg) but not by resting or activated effector T cells (Teff). IL-35 is a heterodimeric protein composed of EBI3 (Epstein-Barr-Virus-induced gene 3) and IL-12a (p35). EBI3 is a downstream target of Foxp3, a transcription factor required for Treg-cell development and function, and thus Treg-cell restriction of IL35 occurs. Regulatory T cells are essential for maintaining self tolerance and preventing autoimmunity, and IL-35 is identified as a molecule that mediates the immune suppression function of Treg-cell. As an inhibitory cytokine, IL-35 induces proliferation of Treg-cell populations but suppresses Th17 cell development. Studies in mice show the absence of either IL-35 chain from Treg-cell reduces the cells' ability to suppress inflammation using an experimental model for inflammatory bowel disease. IL-35 is suggested as a potential target of immunotherapy.
VE:
1 * 25 µG
Artikel-Nr:
(221-1250)
Lieferant:
Bel-Art Products, a Part of SP
Hersteller-Artikelnummer::
F146850035
Lokale Artikelnummer::
BELAF146850035
Beschreibung:
PP
VE:
1 * 12 ST
Lieferant:
FLUOROCHEM
Beschreibung:
2,6-Dibrom-4-(trifluormethyl)anilin
Artikel-Nr:
(BOSSBS-7116R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7116R-FITC
Lokale Artikelnummer::
BOSSBS-7116R-FITC
Beschreibung:
Ro autoantigens are of clinical significance because directed against them are found in most patients with primary Sjqgren syndrome, subacute cutaneous lupus erythematosus (SLE), neonatal lupus erythematosus, ANA-negative lupus erythematosus, and systemic lupus erythematosus-like disease secondary to homozygous C2 or C4 complement deficiency (1). Ro/SSA is a ribonucleoprotein that binds to auto in 35 to 50% of patients with SLE and in up to 97% of patients with Sjqgren syndrome (2). The Ro/SSA particle consists of a single immunoreactive protein noncovalently bound with one of four small RNA molecules (2). Most anti-Ro/SSA-positive sera detect not only the main protein, but also a smaller Ro/SSA protein (2). The genes which encode the smaller and larger proteins map to human chromosomes 11p15.5 and 1q31, respectively (3?). La/SSB is an autoimmune RNA-binding protein that plays a role in the transcription of RNA polymerase III was originally defined by its reactivity with auto from patients with Sjé°ƒren syndrome and SLE (6).
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes proteins of 33, 35 and 41 kDa, which are identified as various isoforms of CD74. Its epitope is localized in the extracellular domain of CD74. CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The CD74 molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, and dendritic cells and by various types of carcinomas. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).
Artikel-Nr:
(BNUM1133-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM1133-50
Lokale Artikelnummer::
BTIUBNUM1133-50
Beschreibung:
Recognizes proteins of 33, 35 and 41 kDa, which are identified as various isoforms of CD74. Its epitope is localized in the extracellular domain of CD74. CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The CD74 molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, and dendritic cells and by various types of carcinomas. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).
VE:
1 * 50 µl
Lieferant:
BOCHEM
Beschreibung:
These scoops are made from aluminium.
Artikel-Nr:
(HECH42386034)
Lieferant:
GLASWARENFABRIK KARL HECHT
Hersteller-Artikelnummer::
42386034
Lokale Artikelnummer::
HECH42386034
Beschreibung:
Klemmen aus POM für Kegelschliffe.
VE:
1 * 5 ST
Lieferant:
BOEKEL SCIENTIFIC
Beschreibung:
Hybridisierungs- und Waschverfahren je nach Verwendungszweck und persönlicher Auswahl. Boekel Scientific bietet eine Auswahl an Hybridisierungsöfen mit u. a. folgenden Funktionen: Digitalanzeige zur einfachen Eingabe und Reproduzierung von Temperatureinstellungen, mikroprozessor- oder proportional gesteuerter Temperaturregelung, kurze Aufheizzeiten, verbesserte Heizungsleistung und natürliche oder forcierte Luftumwälzung.
Lieferant:
Sigma-Aldrich
Beschreibung:
2,6-Dimethoxy-p-kresol, Sigma-Aldrich®
Lieferant:
Biotium
Beschreibung:
Recognizes proteins of 33, 35 and 41 kDa, which are identified as various isoforms of CD74. Its epitope is localized in the extracellular domain of CD74. CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The CD74 molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, and dendritic cells and by various types of carcinomas. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).
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