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1-Methylimidazol-5-carbonsäure
Artikel-Nr:
(METN52005373)
Lieferant:
Mettler - Toledo
Hersteller-Artikelnummer::
52005373
Lokale Artikelnummer::
METN52005373
Beschreibung:
The low-maintenance pH probe InPro 3250 series with factory-filled, pre-pressurized liquid electrolyte are suited to an extensive range of applications in the biotechnology, pharmaceutical and chemical process industries.
VE:
1 * 1 ST
Lieferant:
Thermo Scientific
Beschreibung:
2,4-Dibrom-6-(trifluormethyl)anilin
Lieferant:
Bernd Kraft
Beschreibung:
Natriumchlorid 0.01 mol/l (0.01 N) in wässriger Lösung
Lieferant:
MP Biomedicals
Beschreibung:
Colorless, clear solution at 10 g + 100 ml, in water (Lit.).
Artikel-Nr:
(PRSI77-060)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-060
Lokale Artikelnummer::
PRSI77-060
Beschreibung:
The 11B11 monoclonal antibody specifically reacts with mouse 14 kDa cytokine IL-4, expressed by the activated NKT cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen.The 11B11 antibody neutralizes the IL-4 cytokine.
VE:
1 * 0,5 mg
New Product
Lieferant:
Alfa Aesar
Beschreibung:
Stabilized with 250 ppm BHT
Lieferant:
MP Biomedicals
Beschreibung:
Acid fuchsin is one of the dyes used in Masson′s trichome stain where it is used to distinguish muscle from collagen.
Artikel-Nr:
(WITG2.132.001)
Lieferant:
WITEG LABORTECHNIK
Hersteller-Artikelnummer::
2.132.001
Lokale Artikelnummer::
WITG2.132.001
Beschreibung:
These borosilicate glass chromatography columns have fused-in sintered glass discs, ST-stopcock, with solid plug and screw-thread retaining nut.
VE:
1 * 1 ST
Artikel-Nr:
(PRSI77-059)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-059
Lokale Artikelnummer::
PRSI77-059
Beschreibung:
The 11B11 monoclonal antibody specifically reacts with mouse 14 kDa cytokine IL-4, expressed by the activated NKT cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen.The 11B11 antibody neutralizes the IL-4 cytokine.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(BOSSBS-1135R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1135R-HRP
Lokale Artikelnummer::
BOSSBS-1135R-HRP
Beschreibung:
c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labeling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine kinase in human embryonic kidney 293T cells. We have identified 10 known substrates and interactors of c-Src and Src family kinases along with 26 novel substrates. We have experimentally validated 4 of the novel proteins (NICE-4, RNA binding motif 10, FUSE-binding protein 1 and TRK-fused gene) as direct substrates of c-Src using in vitro kinase assays and cotransfection experiments. Significantly, using a c-Src specific inhibitor, we were also able to implicate 3 novel substrates (RNA binding motif 10, EWS1 and Bcl-2 associated transcription factor) in PDGF signaling. Finally, to identify the exact tyrosine residues that are phosphorylated by c-Src on the novel c-Src substrates, we designed custom peptide microarrays containing all possible tyrosine-containing peptides (312 unique peptides) and their mutant counterparts containing a Tyr -->Phe substitution from 14 of the identified substrates. Using this platform, we identified 34 peptides that are phosphorylated by c-Src. We have demonstrated that SILAC-based quantitative proteomics approach is suitable for identification of substrates of nonreceptor tyrosine kinases and can be coupled with peptide microarrays for high-throughput identification of substrate phosphopeptides.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1135R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1135R-A555
Lokale Artikelnummer::
BOSSBS-1135R-A555
Beschreibung:
c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labeling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine kinase in human embryonic kidney 293T cells. We have identified 10 known substrates and interactors of c-Src and Src family kinases along with 26 novel substrates. We have experimentally validated 4 of the novel proteins (NICE-4, RNA binding motif 10, FUSE-binding protein 1 and TRK-fused gene) as direct substrates of c-Src using in vitro kinase assays and cotransfection experiments. Significantly, using a c-Src specific inhibitor, we were also able to implicate 3 novel substrates (RNA binding motif 10, EWS1 and Bcl-2 associated transcription factor) in PDGF signaling. Finally, to identify the exact tyrosine residues that are phosphorylated by c-Src on the novel c-Src substrates, we designed custom peptide microarrays containing all possible tyrosine-containing peptides (312 unique peptides) and their mutant counterparts containing a Tyr -->Phe substitution from 14 of the identified substrates. Using this platform, we identified 34 peptides that are phosphorylated by c-Src. We have demonstrated that SILAC-based quantitative proteomics approach is suitable for identification of substrates of nonreceptor tyrosine kinases and can be coupled with peptide microarrays for high-throughput identification of substrate phosphopeptides.
VE:
1 * 100 µl
Lieferant:
Spectrum Chemical
Beschreibung:
BSE/TSE statement (available upon request)
Allergen statement (available upon request)
Lieferant:
Sigma-Aldrich
Beschreibung:
L(+)-Weinsäure ≥99,7% FCC, FG, Sigma-Aldrich®
Lieferant:
FLUOROCHEM
Beschreibung:
1-(2,5-Xylyl)piperazin
Artikel-Nr:
(GENO786-856)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
786-856
Lokale Artikelnummer::
GENO786-856
Beschreibung:
DNAmark™ 100 bp Plus ladder consists of 14 DNA fragments ranging in size from 100 to 3000 base pairs (bp). The 500 bp and 1200 bp fragment are present at increased intensity to allow easy identification. All fragments are precisely quantified and mixed during the production. For 5 µl loading, all fragments except 500 bp and 1200 bp are 40 ng. The 500 bp and 1200 bp fragment are 100 ng.
VE:
1 * 1 KIT
Lieferant:
Bernd Kraft
Beschreibung:
di-Natrium-L(+)-tartrat Dihydrat, reinst
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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