Artikel-Nr:
(BOSSBS-12388R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12388R-CY7
Lokale Artikelnummer::
BOSSBS-12388R-CY7
Beschreibung:
KIF7 is a 1,343 amino acid protein expressed in embryonic stem cells, melanotic melanoma and Jurkat T-cells. KIF7 is a member of the KIF27 subfamily of the kinesin-like protein family and contains one kinesin-motor domain. It is suggested that KIF7 may participate in the Hedgehog (Hh) signaling pathway by regulating the proteolysis and stability of GLI transcription factors. Hedgehog (Hh) signaling plays a critical role in embryonic development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11174R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11174R
Lokale Artikelnummer::
BOSSBS-11174R
Beschreibung:
KY peptidase (Kyphoscoliosis peptidase) is a 561 amino acid cytoskeleton protease that interacts with several sarcomeric cytoskeletal proteins, including Filamin 2. KY peptidase probably plays a role in the maturation, function and stabilization of the neuromuscular junction. KY-null mouse mutants exhibit distinct irregular subceullular Filamin 2 localization, suggesting that KY peptidase deficiency may be the cause of several types of limb-girdle muscular dystrophies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15453R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15453R-HRP
Lokale Artikelnummer::
BOSSBS-15453R-HRP
Beschreibung:
HEMK2 is a 214 amino acid protein that belongs to the methyltransferase superfamily and exists as multiple alternatively spliced isoforms. The gene encoding HEMK2 maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1,5% of the human genome. Chromosome 21-associated disorders include Alzheimer's disease, amyotrophic lateral sclerosis and, most notably, Down syndrome (also known as trisomy 21).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12877R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12877R
Lokale Artikelnummer::
BOSSBS-12877R
Beschreibung:
Predominantly localized to the nucleolus, BOP1 (Block of proliferation 1 protein) is a 746 amino acid highly conserved non-ribosomal protein that is involved in ribosome biogenesis. Truncation of the amino terminus of BOP1 leads to cell growth arrest in the G1 phase and specific inhibition of 28S and 5.8S rRNA synthesis, as well as a deficit in the cytosolic 60S ribosomal subunit. This suggests that BOP1 is involved in the formation of mature rRNAs and in the biogenesis of the 60S ribosomal subunit. BOP1 physically interacts with pescadillo (a protein involved in cell proliferation) and enables efficient incorporation of pescadillo into the nucleolar preribosomal complexes, thereby affecting rRNA maturation and the cell cycle. The BOP1-pescadillo complex is also necessary for biogenesis of 60S ribosomal subunits. Deregulation of BOP1 may lead to colorectal tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0813R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0813R-CY7
Lokale Artikelnummer::
BOSSBS-0813R-CY7
Beschreibung:
Casein is the name for a family of related phosphoproteins. These proteins are commonly found in mammalian milk, making up 80% of the proteins in cow milk and between 20% and 45% of the proteins in human milk. Casein has a wide variety of uses, from being a major component of cheese, to use as a food additive, to a binder for safety matches. As a food source, casein supplies amino acids; carbohydrates; and two inorganic elements, calcium and phosphorus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0813R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0813R-CY5.5
Lokale Artikelnummer::
BOSSBS-0813R-CY5.5
Beschreibung:
Casein is the name for a family of related phosphoproteins. These proteins are commonly found in mammalian milk, making up 80% of the proteins in cow milk and between 20% and 45% of the proteins in human milk. Casein has a wide variety of uses, from being a major component of cheese, to use as a food additive, to a binder for safety matches. As a food source, casein supplies amino acids; carbohydrates; and two inorganic elements, calcium and phosphorus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12877R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12877R-A350
Lokale Artikelnummer::
BOSSBS-12877R-A350
Beschreibung:
Predominantly localized to the nucleolus, BOP1 (Block of proliferation 1 protein) is a 746 amino acid highly conserved non-ribosomal protein that is involved in ribosome biogenesis. Truncation of the amino terminus of BOP1 leads to cell growth arrest in the G1 phase and specific inhibition of 28S and 5.8S rRNA synthesis, as well as a deficit in the cytosolic 60S ribosomal subunit. This suggests that BOP1 is involved in the formation of mature rRNAs and in the biogenesis of the 60S ribosomal subunit. BOP1 physically interacts with pescadillo (a protein involved in cell proliferation) and enables efficient incorporation of pescadillo into the nucleolar preribosomal complexes, thereby affecting rRNA maturation and the cell cycle. The BOP1-pescadillo complex is also necessary for biogenesis of 60S ribosomal subunits. Deregulation of BOP1 may lead to colorectal tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1215R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1215R-A680
Lokale Artikelnummer::
BOSSBS-1215R-A680
Beschreibung:
This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyses the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1160R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1160R-A750
Lokale Artikelnummer::
BOSSBS-1160R-A750
Beschreibung:
Gelsolin is a calcium dependent actin binding protein. It is a potent modulator of actin filament length and gelation. Gelsolin has been shown to exist in at least two variant forms, cytoplasmic gelsolin and plasma gelsolin. Plasma gelsolin has also been called actin depolymerizing factor (ADF) or brevin. Human plasma and rabbit macrophage gelsolins differ by the presence of a 25 amino acid residue extension at the NH2 terminus in the human plasma gelsolin, which appears to account for the difference in relative molecular weights.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8861R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8861R-A350
Lokale Artikelnummer::
BOSSBS-8861R-A350
Beschreibung:
STOML2 is a 356 amino acid member of the mec-2 family of proteins. Expressed ubiquitously at low levels, STOML2 is highly expressed in heart, liver and pancreas. STOML2 is localized to the cytoplasm with some distribution on the membrane. STOML2 was first identified as an overexpressed protein in human endometrial adenocarcinoma. Changes in cell growth in samples with different levels of STOML2 indicate that STOML2 could play a role in endometrial tumorigenesis. STOML2 is also thought to play a role in regulating ion channel conductances or the organization of sphingolipid and cholesterol-rich lipid rafts.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Lieferant:
Biotium
Beschreibung:
UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Artikel-Nr:
(BOSSBS-12881R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12881R-HRP
Lokale Artikelnummer::
BOSSBS-12881R-HRP
Beschreibung:
ABTB1 is a 478 amino acid protein localized to the cytoplasm. ABTB1 contains two ANK repeats and two BTB (POZ) domains. The BTB (POZ) domain is thought to be involved in protein-protein interactions, and may indicate a role of ABTB1 in developmental processes. It has also been suggested that ABTB1 may be a mediator of the PTEN growth-suppressive signaling pathway. ABTB1 is ubiquitously expressed in all fetal tissues, with lower levels of expression found in adult heart. ABTB1 exists as four isoforms produced by alternative splicing.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Artikel-Nr:
(BOSSBS-8861R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8861R-A680
Lokale Artikelnummer::
BOSSBS-8861R-A680
Beschreibung:
STOML2 is a 356 amino acid member of the mec-2 family of proteins. Expressed ubiquitously at low levels, STOML2 is highly expressed in heart, liver and pancreas. STOML2 is localised to the cytoplasm with some distribution on the membrane. STOML2 was first identified as an overexpressed protein in human endometrial adenocarcinoma. Changes in cell growth in samples with different levels of STOML2 indicate that STOML2 could play a role in endometrial tumorigenesis. STOML2 is also thought to play a role in regulating ion channel conductances or the organisation of sphingolipid and cholesterol-rich lipid rafts.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13314R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13314R
Lokale Artikelnummer::
BOSSBS-13314R
Beschreibung:
Glial cells missing homolog 2 (GCM2), also known as Chorion-specific transcription factor GCMb, is a 506 amino acid nuclear protein. GCM2 is a transcription factor that acts as an essential regulator of parathyroid development. GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. GCM2 contains one N-terminal GCM domain, which has DNA binding activity. Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, an autosomal recessive condition characterized by hypocalcemia and hyperphosphatemia.
VE:
1 * 100 µl
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