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Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-12193R-A555
Lokale Artikelnummer:: BOSSBS-12193R-A555
Beschreibung:   Transcription factor required for formation of positional identity in the developing retina, regionalization of the optic chiasm and morphogenesis of the kidney. Can neuralize ectodermal cells directly By similarity. Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis. Probable transcription factor involved in embryogenesis and somatogenesis. FOXD1 is involved in regulating inflammation as well as kidney and retinal development. FOXD1 regulates the activity of NFAT and NFkB. Deficiency of FOXD1 results in multiorgan systemic inflammation, exaggerated Th cell-derived cytokine production, and T cell proliferation in autogolgous MLRs. In kidneys, FOXD1 controls the production of signals required for the normal transition of induced mesenchyme into tubular epithelium and full growth and branching of the collecting system. Deletion of FOXD1 results in renal abnormalities. FOXD2 acts as a modulator of T cell activation.
VE:  1 * 100 µl
Artikel-Nr: (PRSI91-623)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 91-623
Lokale Artikelnummer:: PRSI91-623
Beschreibung:   CD5L, also known as CT-2,SP-alpha and CD5 antigen-like. It is expressed by the gene Cd5l. The protein is expressed in thymus, liver, spleen and lymph nodes. CD5L contains 3 SRCR domains, which are 102, 101, and 103aa.long. CD5L is glycosylated during post-translational modification. It may play a role in the regulation of the immune system, and seems to play a role as an inhibitor of apoptosis.
VE:  1 * 50 µG
Lieferant:  Thermo Orion
Hersteller-Artikelnummer:: 8157BNUMD
Lokale Artikelnummer:: ORIO8157BNUMD
Beschreibung:   This electrode with built-in temperature sensor is ideal for any application where the use of metallic reference electrodes would contaminate the samples. Compared to conventional electrodes, the proven ROSS reference system exhibits superior stability in measurements, faster response, greater accuracy and precision when measuring samples that vary in temperature or when calibrating in temperatures that differ from the samples.
VE:  1 * 1 ST

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-11980R-A647
Lokale Artikelnummer:: BOSSBS-11980R-A647
Beschreibung:   The calcium binding protein (CaBP) family shares much similarity to calmodulin. It has been shown that CaBP proteins can substitute functionally for, and probably augment the function of, calmodulin. Calcium binding proteins are a crucial part of calcium mediated cellular signal transduction in the central nervous system. There are several members of the family with varying expression patterns. CaBP1 and CaBP2 can be expressed as multiple, alternatively spliced variants in brain and retina. CaBP3, CaBP4 and CaBP 5 are restricted to retinal rod and cone cells.
VE:  1 * 100 µl
Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-3943R-A680
Lokale Artikelnummer:: BOSSBS-3943R-A680
Beschreibung:   G proteins are composed of 3 units, alpha, beta and gamma and are involved in the modulation and transduction of various transmembrane signalling systems. There are families of related genes for each subunit. GNB3 encodes a beta subunit. Beta subunits are required for GTPase activity, for replacement of GDP by GTP, regulate alpha subunits and for G protein-effector interactions. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity and is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity.
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-6867R-CY3
Lokale Artikelnummer:: BOSSBS-6867R-CY3
Beschreibung:   The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008].
VE:  1 * 100 µl
Artikel-Nr: (BOSSBS-3943R-CY3)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-3943R-CY3
Lokale Artikelnummer:: BOSSBS-3943R-CY3
Beschreibung:   G proteins are composed of 3 units, alpha, beta and gamma and are involved in the modulation and transduction of various transmembrane signalling systems. There are families of related genes for each subunit. GNB3 encodes a beta subunit. Beta subunits are required for GTPase activity, for replacement of GDP by GTP, regulate alpha subunits and for G protein-effector interactions. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity and is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity.
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-6804R-CY7
Lokale Artikelnummer:: BOSSBS-6804R-CY7
Beschreibung:   This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-13391R-A350
Lokale Artikelnummer:: BOSSBS-13391R-A350
Beschreibung:   Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
VE:  1 * 100 µl
Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-7688R-A750
Lokale Artikelnummer:: BOSSBS-7688R-A750
Beschreibung:   This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-10042R-A350
Lokale Artikelnummer:: BOSSBS-10042R-A350
Beschreibung:   Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-7688R-A647
Lokale Artikelnummer:: BOSSBS-7688R-A647
Beschreibung:   This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
VE:  1 * 100 µl
Artikel-Nr: (BOSSBS-6909R-CY5)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-6909R-CY5
Lokale Artikelnummer:: BOSSBS-6909R-CY5
Beschreibung:   The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. [provided by RefSeq, Jul 2008].
VE:  1 * 100 µl
Artikel-Nr: (BOSSBS-10042R-CY5)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-10042R-CY5
Lokale Artikelnummer:: BOSSBS-10042R-CY5
Beschreibung:   Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
VE:  1 * 100 µl
Artikel-Nr: (BOSSBS-13391R-CY7)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-13391R-CY7
Lokale Artikelnummer:: BOSSBS-13391R-CY7
Beschreibung:   Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
VE:  1 * 100 µl

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 92-445
Lokale Artikelnummer:: PRSI92-445
Beschreibung:   tumour necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is the ligand for CD134 and is expressed on such cells as DC2s enabling amplification of Th2 cell differentiation. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. It has been found association with systemic lupus erythematosus, No association with occurrence of atherosclerosis.
VE:  1 * 50 µG
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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