5-(4-Hydroxyphenyl)thiophene-2-carboxylic+acid
Artikel-Nr:
(BOSSBS-15335R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15335R-A750
Lokale Artikelnummer::
BOSSBS-15335R-A750
Beschreibung:
Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf62 gene product has been provisionally designated C9orf62 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9490R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9490R-A555
Lokale Artikelnummer::
BOSSBS-9490R-A555
Beschreibung:
Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The KIAA1529 gene product has been provisionally designated KIAA1529 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9497R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9497R-CY7
Lokale Artikelnummer::
BOSSBS-9497R-CY7
Beschreibung:
C9orf152 is a 239 amino acid protein encoded by a gene that maps to human chromosome 9q31.3. Chromosome 9 consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15331R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15331R-A750
Lokale Artikelnummer::
BOSSBS-15331R-A750
Beschreibung:
Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf50 gene product has been provisionally designated C9orf50 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(194434-100)
Lieferant:
Merck Millipore (Oncogene)
Hersteller-Artikelnummer::
194434-100
Lokale Artikelnummer::
ONCO194434-100
Beschreibung:
ABTS (Diammonium-2,2'-azinobis[3-ethyl-2,3-dihydrobenzothiazol-6-sulfonat]), Sigma-Aldrich®
VE:
1 * 100 mL
Artikel-Nr:
(EHERC16000000)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C16000000
Lokale Artikelnummer::
EHERC16000000
Beschreibung:
1,1-Dichlor-2,2-bis(4-ethylphenyl)ethan
VE:
1 * 0,1 g
Lieferant:
IKA
Beschreibung:
Schüttler für schonende Mischaufgaben, 2D-Modelle bieten eine Wippbewegung, 3D-Modelle eine dreidimensionale Taumelbewegung. Basic-Modelle verfügen über einen fest eingestellten Neigungswinkel, die digitalen Modelle über einen einstellbaren Neigungswinkel und eine einstellbare Drehzahl. Zum homogenen Mischen in Kolben, Kulturflaschen, Petrischalen und Röhrchen. 3D-Schüttler sind ideal für die Züchtung von Zellkulturen, DNA-Extraktionen, die Verteilung von Zellen sowie das Färben und Entfärben von Gelen. Auch bei Beladungs- und Spannungsschwankungen bleibt die Schütteldrehzahl konstant. Dank verschiedener Aufsätze können die Einheiten für eine Vielzahl an Anwendungen genutzt werden.
Artikel-Nr:
(194430-1)
Lieferant:
Merck Millipore (Oncogene)
Hersteller-Artikelnummer::
194430-1
Lokale Artikelnummer::
ONCO194430-1
Beschreibung:
ABTS™ Chromophore, Diammonium Salt
VE:
1 * 1 g
Artikel-Nr:
(BNUM0700-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0700-50
Lokale Artikelnummer::
BTIUBNUM0700-50
Beschreibung:
This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb cocktail labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
VE:
1 * 50 µl
Lieferant:
Biotium
Beschreibung:
This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.
Lieferant:
Biotium
Beschreibung:
This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
Artikel-Nr:
(BOSSBS-6264R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6264R-A647
Lokale Artikelnummer::
BOSSBS-6264R-A647
Beschreibung:
EMP-2 is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family. Localized to lipid raft domains in the plasma membrane, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium. Specifically, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, as well as Integrins and caveolin-1. In adult tissues, EMP-2 is expressed in heart, lung, ovary and intestine, while fetal expression is highest in kidney, brain and liver. Overexpression of EMP-2 is associated with endometrial adenocarcinoma, suggesting a possible role for EMP-2 in tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12157R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12157R-A488
Lokale Artikelnummer::
BOSSBS-12157R-A488
Beschreibung:
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
VE:
1 * 100 µl
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