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2-Chloro-6-fluoroquinoline-3-carboxaldehyde
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2-Chloro-6-fluoroquinoline-3-carboxaldehyde
Artikel-Nr:
(BOSSBS-15130R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15130R-A555
Lokale Artikelnummer::
BOSSBS-15130R-A555
Beschreibung:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. The C21orf88 gene product has been provisionally designated C21orf88 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15130R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15130R-CY7
Lokale Artikelnummer::
BOSSBS-15130R-CY7
Beschreibung:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. The C21orf88 gene product has been provisionally designated C21orf88 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11406R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11406R-HRP
Lokale Artikelnummer::
BOSSBS-11406R-HRP
Beschreibung:
GIOT-1 is a 563 amino acid protein belonging to the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, GIOT-1 is widely expressed in tissues, with highest levels in liver, kidney, small intestine, pancreas and thymus. GIOT-1 contains 12 C2H2-type zinc fincers and one KRAB domain. Because the KRAB domain functions as a transcriptional repressor when attached to the template DNA, GIOT-1 is thought to be involved in transcriptional regulation. The gene encoding GIOT-1 is localized to chromosome 19q13.12 and two isoforms of GIOT-1 exist as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12919R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12919R-CY5
Lokale Artikelnummer::
BOSSBS-12919R-CY5
Beschreibung:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9975R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9975R-A750
Lokale Artikelnummer::
BOSSBS-9975R-A750
Beschreibung:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukaemias. The C21orf62 gene product has been provisionally designated C21orf62 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11406R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11406R-A350
Lokale Artikelnummer::
BOSSBS-11406R-A350
Beschreibung:
GIOT-1 is a 563 amino acid protein belonging to the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, GIOT-1 is widely expressed in tissues, with highest levels in liver, kidney, small intestine, pancreas and thymus. GIOT-1 contains 12 C2H2-type zinc fincers and one KRAB domain. Because the KRAB domain functions as a transcriptional repressor when attached to the template DNA, GIOT-1 is thought to be involved in transcriptional regulation. The gene encoding GIOT-1 is localized to chromosome 19q13.12 and two isoforms of GIOT-1 exist as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12919R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12919R-FITC
Lokale Artikelnummer::
BOSSBS-12919R-FITC
Beschreibung:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15130R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15130R-A647
Lokale Artikelnummer::
BOSSBS-15130R-A647
Beschreibung:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. The C21orf88 gene product has been provisionally designated C21orf88 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11406R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11406R-A555
Lokale Artikelnummer::
BOSSBS-11406R-A555
Beschreibung:
GIOT-1 is a 563 amino acid protein belonging to the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, GIOT-1 is widely expressed in tissues, with highest levels in liver, kidney, small intestine, pancreas and thymus. GIOT-1 contains 12 C2H2-type zinc fincers and one KRAB domain. Because the KRAB domain functions as a transcriptional repressor when attached to the template DNA, GIOT-1 is thought to be involved in transcriptional regulation. The gene encoding GIOT-1 is localized to chromosome 19q13.12 and two isoforms of GIOT-1 exist as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11406R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11406R-A750
Lokale Artikelnummer::
BOSSBS-11406R-A750
Beschreibung:
GIOT-1 is a 563 amino acid protein belonging to the Kr_ppel C2H2-type zinc-finger protein family. localised to the nucleus, GIOT-1 is widely expressed in tissues, with highest levels in liver, kidney, small intestine, pancreas and thymus. GIOT-1 contains 12 C2H2-type zinc fincers and one KRAB domain. Because the KRAB domain functions as a transcriptional repressor when attached to the template DNA, GIOT-1 is thought to be involved in transcriptional regulation. The gene encoding GIOT-1 is localised to chromosome 19q13.12 and two isoforms of GIOT-1 exist as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9976R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9976R-A680
Lokale Artikelnummer::
BOSSBS-9976R-A680
Beschreibung:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukaemias. The C21orf128 gene product has been provisionally designated C21orf128 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8346R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8346R-A750
Lokale Artikelnummer::
BOSSBS-8346R-A750
Beschreibung:
FGFR1OP2 belongs to the SIKE family. The FGFR1OP2 (FGFR1 oncogene partner 2) gene was identified through its involvement in a fusion with the FGFR1 gene. FGFR1OP2 may be involved in the wound healing pathway. It is expressed in bone marrow, spleen and thymus. A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterised by myeloid hyperplasia, eosinophilia and T cell or B cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9503R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9503R-A680
Lokale Artikelnummer::
BOSSBS-9503R-A680
Beschreibung:
This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged.
VE:
1 * 100 µl
Artikel-Nr:
(705-0118)
Lieferant:
Hach
Hersteller-Artikelnummer::
23032
Lokale Artikelnummer::
HACH23032
Beschreibung:
Kaliumhydroxid 12 mol/l (12 N) in wässriger Lösung
VE:
1 * 100 mL
Lieferant:
Biotium
Beschreibung:
This MAb reacts with an N-terminal epitope (aa 16-25) of both wild type and mutated p53. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. In most transformed and tumor cells the concentration of p53 is increased 51000 fold over the minute concentrations (1000 molecules cell) in normal cells, principally due to the increased half-life (4 h) compared to that of the wild-type (20 min). p53 Localizes in the nucleus, but is detectable at the plasma membrane during mitosis and when certain mutations modulate cytoplasmic/nuclear distribution. Mutations arise with an average frequency of 70% but incidence varies from zero in carcinoid lung tumors to 97% in primary melanomas. High concentrations of p53 protein are transiently expressed in human epidermis and superficial dermal fibroblasts following mild ultraviolet irradiation. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia.
Lieferant:
VWR Collection
Beschreibung:
Safe-T-Flex Kappen zeichnen sich durch ein einzigartiges, flexibles, selbstdichtendes Design aus. Sie dichten sicher außen an der Reagenzglaslippe ab und können mit einer Hand geöffnet werden. Dank der festen Dichtung ist der Schutz der Serumproben gewährleistet und es wird so verhindert dass diese auslaufen oder verdunsten. Diese Spezialdichtung schützt gegen die Aerosole hoch infektiöser Organismen wie TB und dem HTLV-III-Virus. Sie sind für eine einfache Probenidentifizierung farbig kodiert und bieten Schutz gegen Kreuzkontamination. Die Oberseite der Kappe kann auch mit abriebfester Tinte nummeriert oder beschriftet werden. Die selbstschließende Kappe sitzt in jeder Position fest und ermöglicht einen sicheren Transport. Der flüssigkeitsdichte Verschluss hält Zentrifugieren, Rühren, Kühlen und Gefrieren stand.
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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