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Methyl+3-bromo-2-chloro-6-fluorobenzoate
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Methyl+3-bromo-2-chloro-6-fluorobenzoate
Artikel-Nr:
(BOSSBS-8325R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8325R-FITC
Lokale Artikelnummer::
BOSSBS-8325R-FITC
Beschreibung:
Cell cycle progression is subject to arrest at G1 and G2 checkpoints in response to DNA damage, presumably to allow time for DNA repair prior to entry into S and M phase, respectively. The p53 tumor suppressor is required for one such G1 checkpoint and functions to upregulate expression of GADD 45 and the mitotic inhibitory protein p21. GADD 45 stimulates DNA excision repair in vitro and inhibits entry of cells into S phase, and it apparently acts in concert with GADD 153 in inducing growth arrest. A related DNA-damage inducible gene, GADD 34 synergizes with GADD 45 or GADD 153 in suppressing cell growth. PEG-3 (progression elevated gene-3) shares significant homology with GADD 34 and is inducible by DNA damage. An additional GADD related gene, PA26, is a possible target of p53. Three isoforms of PA26 have been identified as PA26-T1, PA26-T2 and PA26-T3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6072R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6072R-A488
Lokale Artikelnummer::
BOSSBS-6072R-A488
Beschreibung:
This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(SIAL91660-10ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
91660-10ML
Lokale Artikelnummer::
SIAL91660-10ML
Beschreibung:
Tridodecylamin (Wasserstoff-Ionophor I), Sigma-Aldrich®
VE:
1 * 10 mL
Lieferant:
Advanced Chromatography Technologies
Beschreibung:
Avantor® ACE® Excel® C18-Amid ist eine einzigartig gestaltete stationäre Phase, die eine verbesserte Retention polarer Verbindungen, eine verbesserte phenolische Auflösung und eine alternative Selektivität zu C18-gebundenen Säulen bietet. Diese kapillaren bis präparativen Edelstahlsäulen sind in einer Vielzahl von Partikelgrößen und -abmessungen erhältlich.
Artikel-Nr:
(BOSSBS-3512R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3512R-CY3
Lokale Artikelnummer::
BOSSBS-3512R-CY3
Beschreibung:
NuMA (Nuclear Mitotic Apparatus Protein) is an intranuclear protein and present in nucleus during interphase. At the onset of mitosis, it redistributes from the nucleus to two centrosomal structures that later will become part of the mitotic spindle pole. After anaphase, the protein redistributes from the spindle polar region into reforming nucleus. NuMA is an essential protein during mitosis for the terminal phases of chromosome separation and/or nuclear reassembly. Recently a study shows that NuMA is cleaved to a 180 to 200kDa during apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(7450-07)
Lieferant:
Avantor
Lokale Artikelnummer::
BAKR7450-07
Beschreibung:
BAKERBOND spe™ Amino-Carbon ist eine Zweiphasen-Feststoffextraktionssäule, die mit kugelförmiger Aktivkohle (untere Schicht) und aminopropylmodifizierter Silikaphase (obere Schicht) mit polaren, schwach anionischen Eigenschaften gefüllt ist. Entwickelt für die Analyse von Pestizidrückständen in landwirtschaftlichen Erzeugnissen.
VE:
1 * 30 ST
Artikel-Nr:
(BOSSBS-6769R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6769R-A555
Lokale Artikelnummer::
BOSSBS-6769R-A555
Beschreibung:
Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6558R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6558R-HRP
Lokale Artikelnummer::
BOSSBS-6558R-HRP
Beschreibung:
May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2746R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2746R-CY5
Lokale Artikelnummer::
BOSSBS-2746R-CY5
Beschreibung:
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7925R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7925R-CY7
Lokale Artikelnummer::
BOSSBS-7925R-CY7
Beschreibung:
Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly.Tissue specificity: Widely expressed. Present in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle. Also found in adult cell lines.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3103R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3103R-A488
Lokale Artikelnummer::
BOSSBS-3103R-A488
Beschreibung:
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3103R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3103R-CY7
Lokale Artikelnummer::
BOSSBS-3103R-CY7
Beschreibung:
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7925R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7925R-A488
Lokale Artikelnummer::
BOSSBS-7925R-A488
Beschreibung:
Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly.Tissue specificity: Widely expressed. Present in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle. Also found in adult cell lines.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5634R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5634R-A750
Lokale Artikelnummer::
BOSSBS-5634R-A750
Beschreibung:
NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. Required for genomic stability. Regulates the production of TNF protein. Has a role in the regulation of life span (By similarity). Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. On DNA damage, promotes DNA end resection via deacetylation of RBBP8. Has very weak deacetylase activity and can bind NAD(+) in the absence of acetylated substrate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5634R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5634R-A555
Lokale Artikelnummer::
BOSSBS-5634R-A555
Beschreibung:
NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. Required for genomic stability. Regulates the production of TNF protein. Has a role in the regulation of life span (By similarity). Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. On DNA damage, promotes DNA end resection via deacetylation of RBBP8. Has very weak deacetylase activity and can bind NAD(+) in the absence of acetylated substrate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5634R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5634R-A488
Lokale Artikelnummer::
BOSSBS-5634R-A488
Beschreibung:
NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. Required for genomic stability. Regulates the production of TNF protein. Has a role in the regulation of life span (By similarity). Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. On DNA damage, promotes DNA end resection via deacetylation of RBBP8. Has very weak deacetylase activity and can bind NAD(+) in the absence of acetylated substrate.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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