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Testo
Artikel-Nr:
(BOSSBS-11127R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11127R-A350
Lokale Artikelnummer::
BOSSBS-11127R-A350
Beschreibung:
Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1014R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1014R-HRP
Lokale Artikelnummer::
BOSSBS-1014R-HRP
Beschreibung:
Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9166R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9166R-HRP
Lokale Artikelnummer::
BOSSBS-9166R-HRP
Beschreibung:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternative splicing of this gene generates three transcript variants, named alpha, beta and gamma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13351R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13351R-A750
Lokale Artikelnummer::
BOSSBS-13351R-A750
Beschreibung:
This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11681R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11681R-A350
Lokale Artikelnummer::
BOSSBS-11681R-A350
Beschreibung:
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4081R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4081R-A750
Lokale Artikelnummer::
BOSSBS-4081R-A750
Beschreibung:
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localises to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11681R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11681R-A555
Lokale Artikelnummer::
BOSSBS-11681R-A555
Beschreibung:
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11681R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11681R-A488
Lokale Artikelnummer::
BOSSBS-11681R-A488
Beschreibung:
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13470R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13470R-A750
Lokale Artikelnummer::
BOSSBS-13470R-A750
Beschreibung:
Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4081R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4081R-CY5.5
Lokale Artikelnummer::
BOSSBS-4081R-CY5.5
Beschreibung:
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8377R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8377R-A680
Lokale Artikelnummer::
BOSSBS-8377R-A680
Beschreibung:
NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. It may play a role in the inflammatory response, regulating its duration by limiting the period in which class II MHC molecules are induced by IFN gamma. The RING type zinc finger domain interacts with an ubiquitin conjugating enzyme (E2) and facilitates ubiquitination.
VE:
1 * 100 µl
Lieferant:
Spectrum Chemical
Beschreibung:
Dextrin, White Powder is used as water-soluble glue in envelope adhesives, crispness enhancers in food processing and as a thickening agent in pharmaceuticals.
Artikel-Nr:
(BOSSBS-2520R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2520R-CY3
Lokale Artikelnummer::
BOSSBS-2520R-CY3
Beschreibung:
Plays a role as adhesion receptor functioning by homophilic interactions and by clustering. Recruits SH2 domain-containing proteins SH2D1A/SAP. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway. May serve as a marker for hematopoietic progenitor cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13343R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-HRP
Lokale Artikelnummer::
BOSSBS-13343R-HRP
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6031R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6031R-A488
Lokale Artikelnummer::
BOSSBS-6031R-A488
Beschreibung:
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6031R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6031R-FITC
Lokale Artikelnummer::
BOSSBS-6031R-FITC
Beschreibung:
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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