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4-Hydroxy-2,3,5-trifluorobenzoic+acid
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4-Hydroxy-2,3,5-trifluorobenzoic+acid
Artikel-Nr:
(BOSSBS-5004R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5004R
Lokale Artikelnummer::
BOSSBS-5004R
Beschreibung:
PFKFB1 belongs to the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. It forms a homodimer that is involved in both the synthesis and degradation of fructose 2,6-bisphosphate. The activity of this enzyme is thought to regulate glucose homeostasis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8259R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8259R-CY3
Lokale Artikelnummer::
BOSSBS-8259R-CY3
Beschreibung:
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11709R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11709R-CY7
Lokale Artikelnummer::
BOSSBS-11709R-CY7
Beschreibung:
Mutations in the ALS2 gene result in a number of juvenile recessive motor neuron diseases (MNDs), including juvenile primary lateral sclerosis (JPLS), a recessive form of amyotrophic lateral sclerosis (ALS2); infantile onset ascending hereditary spastic paralysis (IAHSP); and a form of complicated hereditary spastic paraplegia (cHSP). The ALS2 gene encodes the Alsin protein. Alsin acts as a guanine nucleotide exchange factor for Rab5, a modulator of the endocytic pathway. Alsin is a cytosolic protein that is associated with small, punctate membrane structures. Therefore, Alsin may mediate membrane transport events, potentially linking endocytic processes and actin cytoskeleton remodeling. The ALS2 C-terminal-like protein (ALS2CL) also modulates Rab 5 activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12142R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12142R-CY7
Lokale Artikelnummer::
BOSSBS-12142R-CY7
Beschreibung:
The membranes of myelinating Schwann cells are joined by tight, gap and adherens junctions, all of which are found in regions of noncompact myelin: the paranodal loops, incisures of Schmidt-Lanterman and mesaxons. Tight junctions help establish polarity in mammalian epithelia by forming a physical barrier that separates apical and basolateral membranes. Pals-associated tight junction protein (PATJ), the human homolog of Drosophila Discs Lost, is differentially localized in myelinating Schwann cells. PATJ associates with Claudin-1, CRB1 (a transmembrane protein that plays a role in epithelial cell polarity and photoreceptor development), and Pals1 (a Lin-7 associated protein). The PATJ/Pals1/CRB1 complex can form a tripartite tight junction in epithelial cells crucial to their integrity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11709R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11709R
Lokale Artikelnummer::
BOSSBS-11709R
Beschreibung:
Mutations in the ALS2 gene result in a number of juvenile recessive motor neuron diseases (MNDs), including juvenile primary lateral sclerosis (JPLS), a recessive form of amyotrophic lateral sclerosis (ALS2); infantile onset ascending hereditary spastic paralysis (IAHSP); and a form of complicated hereditary spastic paraplegia (cHSP). The ALS2 gene encodes the Alsin protein. Alsin acts as a guanine nucleotide exchange factor for Rab5, a modulator of the endocytic pathway. Alsin is a cytosolic protein that is associated with small, punctate membrane structures. Therefore, Alsin may mediate membrane transport events, potentially linking endocytic processes and actin cytoskeleton remodeling. The ALS2 C-terminal-like protein (ALS2CL) also modulates Rab 5 activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11924R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11924R-A647
Lokale Artikelnummer::
BOSSBS-11924R-A647
Beschreibung:
The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth, cell differentiation, oncogenic transformation and the mitotic cycle. PCPTP1, also known as PTPRR (Receptor-type tyrosine-protein phosphatase R), ECPTP, PTPBR7 or PTPRQ, is a 657 amino acid protein that functions to sequester inactive mitogen-activated protein kinases (MAPKs) to the cytoplasm. Expressed primarily in the brain with weaker expression in other parts of the body, PCPTP1 is a receptor-like molecule that is able to dephosphorylate MAPKs, thereby rendering them inactive. Three isoforms of PCPTP1 exist and are designated alpha, beta and gamma. The alpha form is localized to the cell membrane, while the beta and gamma forms are localized to the perinuclear areas within the cytoplasm.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11924R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11924R-A680
Lokale Artikelnummer::
BOSSBS-11924R-A680
Beschreibung:
The protein tyrosine phosphatase (PTP) family of proteins are Signalling molecules that regulate processes such as cell growth, cell differentiation, oncogenic transformation and the mitotic cycle. PCPTP1, also known as PTPRR (Receptor-type tyrosine-protein phosphatase R), ECPTP, PTPBR7 or PTPRQ, is a 657 amino acid protein that functions to sequester inactive mitogen-activated protein kinases (MAPKs) to the cytoplasm. Expressed primarily in the brain with weaker expression in other parts of the body, PCPTP1 is a receptor-like molecule that is able to dephosphorylate MAPKs, thereby rendering them inactive. Three isoforms of PCPTP1 exist and are designated alpha, beta and gamma. The alpha form is localised to the cell membrane, while the beta and gamma forms are localised to the perinuclear areas within the cytoplasm.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12372R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12372R-A488
Lokale Artikelnummer::
BOSSBS-12372R-A488
Beschreibung:
MEGF10 is a 1,140 amino acid protein encoded by the human gene MEGF10. MEGF10 belongs to the MEGF family and contains fifteen EGF-like domains and one EMI domain. The engulfment of dying cells is a specialized form of phagocytosis that is highly conserved across evolution and is mediated by the concerted action of several molecules. MEGF10 is an engulfment receptor protein that localizes to the plasma membrane in a punctuated pattern. The MEGF10 protein shares structural similarities with nematode engulfment receptor cell death abnormal-1 (CED-1). MEGF10 function is modulated by the ATP binding cassette transporter ABCA1, which is an ortholog to CED-7. It is expressed at the cell surface in clusters around cell corpses during engulfment, and during the engulfment of apoptotic thymocytes is recruited to the bottom of the forming phagocytic cup.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12372R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12372R-A647
Lokale Artikelnummer::
BOSSBS-12372R-A647
Beschreibung:
MEGF10 is a 1,140 amino acid protein encoded by the human gene MEGF10. MEGF10 belongs to the MEGF family and contains fifteen EGF-like domains and one EMI domain. The engulfment of dying cells is a specialized form of phagocytosis that is highly conserved across evolution and is mediated by the concerted action of several molecules. MEGF10 is an engulfment receptor protein that localizes to the plasma membrane in a punctuated pattern. The MEGF10 protein shares structural similarities with nematode engulfment receptor cell death abnormal-1 (CED-1). MEGF10 function is modulated by the ATP binding cassette transporter ABCA1, which is an ortholog to CED-7. It is expressed at the cell surface in clusters around cell corpses during engulfment, and during the engulfment of apoptotic thymocytes is recruited to the bottom of the forming phagocytic cup.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12372R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12372R-A555
Lokale Artikelnummer::
BOSSBS-12372R-A555
Beschreibung:
MEGF10 is a 1,140 amino acid protein encoded by the human gene MEGF10. MEGF10 belongs to the MEGF family and contains fifteen EGF-like domains and one EMI domain. The engulfment of dying cells is a specialized form of phagocytosis that is highly conserved across evolution and is mediated by the concerted action of several molecules. MEGF10 is an engulfment receptor protein that localizes to the plasma membrane in a punctuated pattern. The MEGF10 protein shares structural similarities with nematode engulfment receptor cell death abnormal-1 (CED-1). MEGF10 function is modulated by the ATP binding cassette transporter ABCA1, which is an ortholog to CED-7. It is expressed at the cell surface in clusters around cell corpses during engulfment, and during the engulfment of apoptotic thymocytes is recruited to the bottom of the forming phagocytic cup.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0540R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0540R-CY3
Lokale Artikelnummer::
BOSSBS-0540R-CY3
Beschreibung:
HGFA Inhibitor 1 is an endogenous inhibitor of the kunitz-type serine proteinase HGF-activator (HGFA). HGF was first described as a hepatocyte-specific mitogen and survival factor, and has since been shown to exert a variety of actions on many cell types by binding to its MET receptor. HGF is activated by cleavage of the single-chain form to form a two-chain version by HGFA. HGFA Inhibitor 1 also inhibits trypsin, and MTSP-1 (Matriptase), a serine proteinase that also activates HGF. HGFB Inhibitor 1 is a splice variant of HGFA Inhibitor 1, and contains a 16 amino acid insert after the first kringle domain, relative to the HGFA Inhibitor 1 sequence.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9350R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9350R-CY5
Lokale Artikelnummer::
BOSSBS-9350R-CY5
Beschreibung:
Ubiquitin-dependent proteolysis mediates selective destruction of various cell cycle regulators, transcription factors and tumor suppressors. In eukaryotic cells, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome form, facilitating proteolysis. 20S Proteasome ?, also designated macropain subunit C2 or PROS-30, is a prosomal protein involved in a non-lysosomal ATP/ubiquitin-dependent proteolytic pathway. The entire proteasome is composed of at least 15 non-identical subunits which form a highly-ordered ring-shaped structure.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15576R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15576R-A350
Lokale Artikelnummer::
BOSSBS-15576R-A350
Beschreibung:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localises to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0540R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0540R-CY7
Lokale Artikelnummer::
BOSSBS-0540R-CY7
Beschreibung:
HGFA Inhibitor 1 is an endogenous inhibitor of the kunitz-type serine proteinase HGF-activator (HGFA). HGF was first described as a hepatocyte-specific mitogen and survival factor, and has since been shown to exert a variety of actions on many cell types by binding to its MET receptor. HGF is activated by cleavage of the single-chain form to form a two-chain version by HGFA. HGFA Inhibitor 1 also inhibits trypsin, and MTSP-1 (Matriptase), a serine proteinase that also activates HGF. HGFB Inhibitor 1 is a splice variant of HGFA Inhibitor 1, and contains a 16 amino acid insert after the first kringle domain, relative to the HGFA Inhibitor 1 sequence.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1111R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1111R-CY7
Lokale Artikelnummer::
BOSSBS-1111R-CY7
Beschreibung:
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4039R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4039R-CY7
Lokale Artikelnummer::
BOSSBS-4039R-CY7
Beschreibung:
SLC37A4 transports glucose-6-phosphate from the cytoplasm to the lumen of the endoplasmic reticulum. It forms a complex with glucose-6-phosphatase which is responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels.
VE:
1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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