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1-Cyclopropyl-4-piperidinone
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1-Cyclopropyl-4-piperidinone
Artikel-Nr:
(BOSSBS-12888R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12888R-A488
Lokale Artikelnummer::
BOSSBS-12888R-A488
Beschreibung:
The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The gene encoding BRD3 (RING3-like protein) contains two bromodomains and maps to chromosome 9q34. BRD4 (HUNK1 protein) is a nuclear protein involved in the regulation of chromosomal dynamics during mitosis. The testis-specific bromodomain protein BRDT contains a PEST sequence, indicating that it undergoes rapid intracellular degradation. The bromodomain-containing proteins are ubiquitously expressed.
VE:
1 * 100 µl
Artikel-Nr:
(BNUM0206-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0206-50
Lokale Artikelnummer::
BTIUBNUM0206-50
Beschreibung:
Recognizes a protein of 55 kDa, identified as CD4. CD4 is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
VE:
1 * 50 µl
Artikel-Nr:
(BOHLR1125-02)
Lieferant:
Bohlender
Hersteller-Artikelnummer::
R1125-02
Lokale Artikelnummer::
BOHLR1125-02
Beschreibung:
Sammelanschluss zum Sammeln von flüssigen Abfällen aus bis zu 2 HPLC-Anlagen. Kann direkt in Laborabzüge oder Arbeitstische integriert werden. b.safe Waste Pipes leiten flüssige Lösemittelabfälle direkt in angeschlossene Kanister weiter.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-15468R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15468R
Lokale Artikelnummer::
BOSSBS-15468R
Beschreibung:
Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1358R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1358R-FITC
Lokale Artikelnummer::
BOSSBS-1358R-FITC
Beschreibung:
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1358R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1358R-CY7
Lokale Artikelnummer::
BOSSBS-1358R-CY7
Beschreibung:
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12565R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12565R-HRP
Lokale Artikelnummer::
BOSSBS-12565R-HRP
Beschreibung:
ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5754R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5754R-FITC
Lokale Artikelnummer::
BOSSBS-5754R-FITC
Beschreibung:
SP17 is a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5754R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5754R-CY5
Lokale Artikelnummer::
BOSSBS-5754R-CY5
Beschreibung:
SP17 is a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13481R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13481R-HRP
Lokale Artikelnummer::
BOSSBS-13481R-HRP
Beschreibung:
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein is a coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues; the chimeric sequences have been designated RET-II and PTC5. [provided by RefSeq, Feb 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1358R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1358R-CY5.5
Lokale Artikelnummer::
BOSSBS-1358R-CY5.5
Beschreibung:
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13178R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13178R
Lokale Artikelnummer::
BOSSBS-13178R
Beschreibung:
FKBP25 is a member of the immunophilin protein family. The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. They inhibit T-cell proliferation by interrupting two specific cytoplasmic signal transmission pathways. FKBP25 is localized in the nucleus and is expressed in the brain, testis, ovary, and spleen. It may influence immunoregulation and cerebellum development, as well as protein folding and trafficking in neurons. FKBP25 associates with transcriptional repressor protein YY1 and histone deaceltylases, HDAC1 and HDAC2. FKBP25 may contain several casein kinase II phosphorylation sites, which are believed to be important for cell growth regulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1358R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1358R-A350
Lokale Artikelnummer::
BOSSBS-1358R-A350
Beschreibung:
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4236R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4236R-HRP
Lokale Artikelnummer::
BOSSBS-4236R-HRP
Beschreibung:
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13317R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13317R-A680
Lokale Artikelnummer::
BOSSBS-13317R-A680
Beschreibung:
2010013H22Rik; 2210021I22Rik; 2210401J11Rik; 3-galactosyl-O-glycosyl-glycoprotein beta-1; 6-N-acetylglucosaminyltransferase 3; 6-N-acetylglucosaminyltransferase; Beta 1 3 galactosyl O glycosyl glycoprotein beta 1 6 N acetylglucosaminyltransferase 3; Beta-1; Beta1 6 N acetylglucosaminyltransferase 3; beta1 6 N acetylglucosaminyltransferase; C2/4GnT; C24GNT; C2GnT M; C2GnT mucin type; C2GnT-M; C2GnT-mucin type; C2GnT2; C2GNTM; Core 2 beta 1 6 N acetylglucosaminyltransferase II; Core 2/core 4 beta 1 6 N acetylglucosaminyltransferase; Core 2/core 4 beta-1; dI/C2/C4GnT; EC 2.4.1.102; EC 2.4.1.150; GCNT3; GCNT3_HUMAN; Glucosaminyl (N acetyl) transferase 3; Glucosaminyl (N acetyl) transferase 3 mucin type; GnT M; GNTM; hC2GnT M; hC2GnT-M; Mucus-type core 2 beta-1,6-N-acetylglucosaminyltransferase. OTTHUMP00000163601.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1358R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1358R-HRP
Lokale Artikelnummer::
BOSSBS-1358R-HRP
Beschreibung:
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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