Suche >
Drucken
Artikel-Nr:
(MOLEM12040448)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M12040448
Lokale Artikelnummer::
MOLEM12040448
Beschreibung:
Bicin
VE:
1 * 100 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-1361R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1361R-A350
Lokale Artikelnummer::
BOSSBS-1361R-A350
Beschreibung:
Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF1B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L. Negatively regulates; expression of BCL2 and MYOD1, ATF4-dependent transcriptional activation of asparagine synthetase (ASNS), CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG). Inhibits the canonical Wnt signaling pathway by binding to TCF7L2/TCF4, impairing its DNA-binding properties and repressing its transcriptional activity. Plays a regulatory role in the inflammatory response through the induction of caspase-11 (CASP4/CASP11) which induces the activation of caspase-1 (CASP1) and both these caspases increase the activation of pro-IL1B to mature IL1B which is involved in the inflammatory response.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1361R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1361R-FITC
Lokale Artikelnummer::
BOSSBS-1361R-FITC
Beschreibung:
Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF1B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L. Negatively regulates; expression of BCL2 and MYOD1, ATF4-dependent transcriptional activation of asparagine synthetase (ASNS), CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG). Inhibits the canonical Wnt signaling pathway by binding to TCF7L2/TCF4, impairing its DNA-binding properties and repressing its transcriptional activity. Plays a regulatory role in the inflammatory response through the induction of caspase-11 (CASP4/CASP11) which induces the activation of caspase-1 (CASP1) and both these caspases increase the activation of pro-IL1B to mature IL1B which is involved in the inflammatory response.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1549R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1549R-HRP
Lokale Artikelnummer::
BOSSBS-1549R-HRP
Beschreibung:
Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
VE:
1 * 100 µl
Lieferant:
FLUOROCHEM
Beschreibung:
Lithiumbis(trifluormethylsulfonyl)imid
Artikel-Nr:
(1621008.)
Lieferant:
USP
Hersteller-Artikelnummer::
1621008
Lokale Artikelnummer::
USPH1621008
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 500 mg
Artikel-Nr:
(PRSI91-641)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-641
Lokale Artikelnummer::
PRSI91-641
Beschreibung:
Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development.
VE:
1 * 50 µG
Lieferant:
HARVARD APPARATUS
Beschreibung:
The Pump 11 Elite series sets a new standard for handling the challenges of new applications. It has served the research community as the work horse infusion pump for micro and macro fluidic applications including MS calibration, reactor dosing, animal drug/nutritional studies, cell injections, electrospinning and more.
Artikel-Nr:
(HERA158R-AEV-TS)
Lieferant:
HERAEUS
Hersteller-Artikelnummer::
158R-AEV-TS
Lokale Artikelnummer::
HERA158R-AEV-TS
Beschreibung:
Thermo Scientific™ ES Series Lab Refrigerators, designed for general-purpose lab storage.
VE:
1 * 1 ST
Artikel-Nr:
(PROOCIL-PCB-1-C)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-1-C
Lokale Artikelnummer::
PROOCIL-PCB-1-C
Beschreibung:
2-Chlorbiphenyl (PCB Nr. 1)
VE:
1 * 5 mg
Artikel-Nr:
(EHERL16950000EA)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
L16950000EA
Lokale Artikelnummer::
EHERL16950000EA
Beschreibung:
Organic Standard, Simazin (2-Chlor-4,6-bis(ethylamino)-1,3,5-triazin) 10 µg/ml in Ethylacetat, Packung: Glasflasche
VE:
1 * 10 mL
Artikel-Nr:
(BOSSBS-1549R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1549R-A647
Lokale Artikelnummer::
BOSSBS-1549R-A647
Beschreibung:
Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
VE:
1 * 100 µl
Lieferant:
MP Biomedicals
Beschreibung:
An antiseptic and disinfectant agent. It is effective against a wide range of bacteria, some fungi and some viruses, and an agent for the prevention of gingivitis. Commercial ophthalmic products have used this agent to replace thimerosal as a preservative; however, it can cause skin irritation.
Artikel-Nr:
(SIAL236055-100ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
236055-100ML
Lokale Artikelnummer::
SIAL236055-100ML
Beschreibung:
Lithiumaluminiumhydrid 0.5 mol/l in Bis(2-methoxyethyl)ether, Sigma-Aldrich®
VE:
1 * 100 mL
Artikel-Nr:
(MOIN4100T)
Lieferant:
MOINEAU
Hersteller-Artikelnummer::
4100T
Lokale Artikelnummer::
MOIN4100T
Beschreibung:
Maximum/minimum dial thermometer, bi-metallic.
VE:
1 * 1 ST
Lieferant:
KOHLER
Beschreibung:
Spannband aus Edelstahl, rostfrei, mit verzinkter Gewindeschraube.
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
