IGEPAL\\\\\\\\u00AE+CA-630
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-(3-Amino-4-piperidinophenyl)-1-ethanone 95%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-(5-Methyl-4-isoxazolyl)-1-ethanone 95%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-(2,4-Dihydroxy-5-propylphenyl)ethanone
Artikel-Nr:
(BOSSBS-0424R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0424R-A680
Lokale Artikelnummer::
BOSSBS-0424R-A680
Beschreibung:
Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1427R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1427R-A488
Lokale Artikelnummer::
BOSSBS-1427R-A488
Beschreibung:
IRAK or Interleukin-1 Receptor-associated Kinase 1, is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This protein is partially responsible for IL1-induced upregulation of the ubiquitous transcription factor NF-kappa B.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD75547-5G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD75547-5G
Lokale Artikelnummer::
BLDPBD75547-5G
Beschreibung:
3-Iodo-5-methylpyridin-2-ol 98+%
VE:
1 * 5 g
Artikel-Nr:
(BOSSBS-11581R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11581R-A680
Lokale Artikelnummer::
BOSSBS-11581R-A680
Beschreibung:
PDZ-GEF1 is a 1499 amino acid cell membrane protein that functions as a guanine nucleotide exchange factor for Rap 1A, Rap 1B and Rap 2B GTPases. Expressed at highest levels in brain, PDZ-GEF1 is found at low levels in placenta, heart, lung and kidney, and undergoes post-translational phosphorylation following DNA damage. PDZ-GEF1 interacts with MAGI-2 and contains one Ras-GEF domain, a Ras-associating domain, one PDZ (DHR) domain, a single N-terminal Ras-GEF domain and a cyclic nucleotide-binding domain. The gene encoding PDZ-GEF1 maps to human chromosome 4q32.1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12639R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12639R-A680
Lokale Artikelnummer::
BOSSBS-12639R-A680
Beschreibung:
BSPRY is a 402 amino acid protein that localizes to both the membrane and the cytoplasm and contains one B box-type zinc finger and one B30.2/SPRY domain. Existing as two alternatively spliced isoforms, BSPRY interacts with TRPV5 and TRPV6 and is thought to regulate the transport of calcium across the epithelium, probably by inhibiting the activity of TRPV proteins. The gene encoding BSPRY maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11659R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11659R-FITC
Lokale Artikelnummer::
BOSSBS-11659R-FITC
Beschreibung:
PHF2 is a 1,101 amino acid protein belonging to the PHD finger protein family. Members of the PHD finger protein family function as transcriptional regulators that affect gene expression by modulating chromatin structure. Expressed in a wide variety of tissues, PHF2 localizes to the nucleus and contains one PHD-type zinc finger and one JMJC domain, suggesting a possible role for PHF2 in transcription regulation and chromatin remodeling. The gene encoding PHF2 lies in the candidate region for hereditary sensory neuropathy type I (HSN1), a disorder characterized by sensory dysfunction. PHF2 exhists as two isoforms produced by alternative splicing, designated isoform 1 and 2 respectively.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12639R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12639R-A647
Lokale Artikelnummer::
BOSSBS-12639R-A647
Beschreibung:
BSPRY is a 402 amino acid protein that localizes to both the membrane and the cytoplasm and contains one B box-type zinc finger and one B30.2/SPRY domain. Existing as two alternatively spliced isoforms, BSPRY interacts with TRPV5 and TRPV6 and is thought to regulate the transport of calcium across the epithelium, probably by inhibiting the activity of TRPV proteins. The gene encoding BSPRY maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11459R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11459R-A555
Lokale Artikelnummer::
BOSSBS-11459R-A555
Beschreibung:
FARP2 is a 1,545 amino acid protein that contains one FERM domain, one DH domain and two PH domains. It exists as two alternatively spliced isoforms that are abundantly expressed in brain, lung, and testis as well as in embryonic hippocampal and cortical neurons. FARP2 functions as a Rho-guanine nucleotide exchange factor that activates RAC1 and is thought to regulate neurite remodeling of embryonic neurons. Sema3A binding to neuropilin-1 induces the dissociation of FARP2 from plexin-A1, thereby activating FARP2's Rac GEF activity which is critical for repulsion of outgrowing axons and suppression of neuronal adhesion. Downregulation of the FARP2 gene has been implicated in autism.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11459R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11459R-A680
Lokale Artikelnummer::
BOSSBS-11459R-A680
Beschreibung:
FARP2 is a 1545 amino acid protein that contains one FERM domain, one DH domain and two PH domains. It exists as two alternatively spliced isoforms that are abundantly expressed in brain, lung, and testis as well as in embryonic hippocampal and cortical neurons. FARP2 functions as a Rho-guanine nucleotide exchange factor that activates RAC1 and is thought to regulate neurite remodeling of embryonic neurons. Sema3A binding to neuropilin-1 induces the dissociation of FARP2 from plexin-A1, thereby activating FARP2's Rac GEF activity which is critical for repulsion of outgrowing axons and suppression of neuronal adhesion. Downregulation of the FARP2 gene has been implicated in autism.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9628R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9628R-A647
Lokale Artikelnummer::
BOSSBS-9628R-A647
Beschreibung:
C16orf44 is a 616 amino acid protein that contains six Kelch repeats, one BTB/POZ domain and one BTB/Kelch associated (BACK) domain. C16orf44 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, C16orf44 interacts with CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Due to alternative splicing events, two isoforms of C16orf44 are expressed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11459R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11459R-A750
Lokale Artikelnummer::
BOSSBS-11459R-A750
Beschreibung:
FARP2 is a 1545 amino acid protein that contains one FERM domain, one DH domain and two PH domains. It exists as two alternatively spliced isoforms that are abundantly expressed in brain, lung, and testis as well as in embryonic hippocampal and cortical neurons. FARP2 functions as a Rho-guanine nucleotide exchange factor that activates RAC1 and is thought to regulate neurite remodeling of embryonic neurons. Sema3A binding to neuropilin-1 induces the dissociation of FARP2 from plexin-A1, thereby activating FARP2's Rac GEF activity which is critical for repulsion of outgrowing axons and suppression of neuronal adhesion. Downregulation of the FARP2 gene has been implicated in autism.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9107R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9107R
Lokale Artikelnummer::
BOSSBS-9107R
Beschreibung:
The death domain (DD) superfamily of proteins share one or more of the following domains: the DD, DED (death-effector domain), CARD (caspase-recruitment domain) and PYD (Pyrin domain). Each of these domains is characterized by a canonical death domain fold, which consists of a bundle of five or six antiparallel α-helices. As their names suggest, these domains play prominent roles in programmed cell death. ASC2 (apoptosis-associated speck-like protein containing a CARD 2), also known as Pyrin-only protein 1 or PADD-only protein 1, is an 89 amino acid member of the DD superfamily that contains one Pyrin domain. Localized to the cytoplasm, ASC2 interacts with ASC to modulate NF-κB and pro-caspase-1 regulation. ASC2 is predominantly expressed in monocytes, macrophages and granulocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4289R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4289R-CY5
Lokale Artikelnummer::
BOSSBS-4289R-CY5
Beschreibung:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
VE:
1 * 100 µl
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