Artikel-Nr:
(BOSSBS-1945R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1945R-HRP
Lokale Artikelnummer::
BOSSBS-1945R-HRP
Beschreibung:
Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway. Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner. Isoform 1, isoform 2, isoform 3 and isoform 4 stimulate the activity of SLC12A1, SLC12A2 and SLC12A3 and inhibit the activity of SLC12A4, SLC12A5, SLC12A6 and SLC12A7. According to PubMed:19470686, isoform 1 inhibits the activity of SLC12A3.
VE:
1 * 100 µl
Artikel-Nr:
(SCOI285138587)
Lieferant:
SI Analytics
Hersteller-Artikelnummer::
285138587
Lokale Artikelnummer::
SCOI285138587
Beschreibung:
Kaliumchlorid 4.2 mol/l (4.2 N) in wässriger Lösung
VE:
1 * 1 L
Artikel-Nr:
(BOSSBS-2015R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2015R-CY5
Lokale Artikelnummer::
BOSSBS-2015R-CY5
Beschreibung:
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
VE:
1 * 100 µl
Artikel-Nr:
(REGECPNESSR)
Lieferant:
REAGECON
Hersteller-Artikelnummer::
CPNESSR
Lokale Artikelnummer::
REGECPNESSR
Beschreibung:
Reagent is a high purity stable product developed and tested for several Chinese Pharmacopoeia (ChP) applications.
VE:
1 * 500 mL
Lieferant:
COMBI-BLOCKS
Beschreibung:
Kalium(2-fluor-4-(trifluormethyl)phenyl)trifluoroborat
Lieferant:
Honeywell Chemicals
Beschreibung:
Kaliumsulfat ≥99%, Puriss. p.a. ACS, ISO, Fluka™
Lieferant:
Alfa Aesar
Beschreibung:
Dihydrogen hexachloroplatinate(IV) hexahydrate is used for the determination of potassium. It is also used for the purification of platinum by treating it with ammonium chloride flowed by heating of ammonium hexachloroplatinate with hydrogen yields elemental platinum. It also finds application in catalysis, electroplating, photography, platinum mirrors, printing for etching of zinc, producing fine color in glass and porcelain, indelible ink and microscopy. It is a precursor for the preparation of other platinum catalysts.
Lieferant:
Bernd Kraft
Beschreibung:
Kaliumbromat 1/60 mol/l (0.1 N) in wässriger Lösung Reag. Ph. Eur.
Lieferant:
Bernd Kraft
Beschreibung:
Kaliumbromat 1/30 mol/l (0.2 N) in wässriger Lösung Reag. Ph. Eur.
Lieferant:
MP Biomedicals
Beschreibung:
Soluble in water (1 g/3 ml - clear, colorless solution), boiling water (1 g/1,8 ml), glycerol (1 g/14 ml), or ethanol (1 g/250 ml); insoluble in ether or acetone; hydrochloric acid, sodium or magnesium chlorides diminish its solubility in water.
Artikel-Nr:
(HONE01345.9020)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
01345.9020
Lokale Artikelnummer::
HONE01345.9020
Beschreibung:
Kaliumfluorid
VE:
1 * 20 kg
Lieferant:
Bernd Kraft
Beschreibung:
Kaliumpermanganat 0.02 mol/l (0.1 N) in wässriger Lösung
Artikel-Nr:
(BOSSBS-9045R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9045R-HRP
Lokale Artikelnummer::
BOSSBS-9045R-HRP
Beschreibung:
Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2015R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2015R-HRP
Lokale Artikelnummer::
BOSSBS-2015R-HRP
Beschreibung:
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9045R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9045R-A555
Lokale Artikelnummer::
BOSSBS-9045R-A555
Beschreibung:
Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8691R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8691R-A488
Lokale Artikelnummer::
BOSSBS-8691R-A488
Beschreibung:
Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming å subunits (KV), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KV∫, also known as KCNAB1 (potassium voltage-gated channel, shaker-related subfamily, beta member 1), is a 419 amino acid accessory K+ channel protein that exists as three alternatively spliced isoforms and regulates the activity of the pore-forming å subunit. It is expressed in brain, with highest levels detected in caudate nucleus, hippocampus and thalamus.
VE:
1 * 100 µl
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