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2-Amino-4,6-bis(trifluoromethyl)nicotinamide
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2-Amino-4,6-bis(trifluoromethyl)nicotinamide
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 2611-82-7
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 4244-84-2
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 1139-30-6
Artikel-Nr:
(ACRO328540500)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
328540500
Lokale Artikelnummer::
ACRO328540500
Beschreibung:
CAS No.: 129-46-4
VE:
1 * 50 mg
Artikel-Nr:
(BOSSBS-11983R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11983R-A647
Lokale Artikelnummer::
BOSSBS-11983R-A647
Beschreibung:
Voltage-dependent calcium channels are essential for the release of neurotransmitters. L-type (long lasting current) voltage-dependent calcium channels are composed of four subunits: an Alpha1 subunit, a Beta subunit, a Beta subunit and an Alpha2 Gamma subunit. The Beta subunit is encoded by four genes, designated Beta1-Beta 4, all of which contribute to the diversity of calcium currents and are involved in membrane trafficking of the Beta subunit. L-type Ca++ CP Beta 4, also known as CACNB4 (Calcium channel voltage-dependent subunit beta 4), CACNLB4 or CAB4, is a 484 amino acid protein that contains one SH3 domain and is expressed in ovary, brain and smooth muscle. Functioning as one of the four components of the Beta subunit, L-type Ca++ CP Beta 4 increases the peak calcium current in voltage-dependent calcium channels, thereby shifting the voltage dependencies of activation and inactivation and controlling G protein inhibition and Beta membrane targeting. Two isoforms of L-type Ca++ CP Beta4 exist due to alternative splicing events.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 37031-30-4
Artikel-Nr:
(BOSSBS-6223R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6223R-A647
Lokale Artikelnummer::
BOSSBS-6223R-A647
Beschreibung:
BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1136R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1136R-A750
Lokale Artikelnummer::
BOSSBS-1136R-A750
Beschreibung:
Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).[supplied by OMIM].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1683R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1683R-A488
Lokale Artikelnummer::
BOSSBS-1683R-A488
Beschreibung:
Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1136R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1136R-FITC
Lokale Artikelnummer::
BOSSBS-1136R-FITC
Beschreibung:
Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).[supplied by OMIM]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1136R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1136R-A555
Lokale Artikelnummer::
BOSSBS-1136R-A555
Beschreibung:
Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).[supplied by OMIM]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4682R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4682R-A750
Lokale Artikelnummer::
BOSSBS-4682R-A750
Beschreibung:
Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilisation and interferon-gamma production.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9047R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9047R-A680
Lokale Artikelnummer::
BOSSBS-9047R-A680
Beschreibung:
Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarisation and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid <i>in vitro</i>. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6425R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6425R-A750
Lokale Artikelnummer::
BOSSBS-6425R-A750
Beschreibung:
Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11358R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11358R-A488
Lokale Artikelnummer::
BOSSBS-11358R-A488
Beschreibung:
RIMS-binding proteins (RIM-BPs) serve as adaptors during vesicle fusion and release by forming links between synaptic-vesicle fusion apparatuses and calcium channels. Specifically, RIM-BP2 (RIMS binding protein 2), also known as RBP2, is a 1,052 amino acid protein that links L-type Ca++ CP Alpha1D, N-type Ca++ CP Alpha1B, Rim1 and Rim2 during synaptic transmission. RIM-BP2 contains three fibronectin type-III domains and three SH3 domains, which are used to mediate binding to a proline-rich motifs. Existing as three alternatively spliced isoforms, RIM-BP2 is encoded by a gene that maps to human chromosome 12q24.33 and mouse chromosome 5 G1.3.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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