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4-Fluorobenzo[d]thiazol-2(3H)-one
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4-Fluorobenzo[d]thiazol-2(3H)-one
Artikel-Nr:
(BOSSBS-8021R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8021R
Lokale Artikelnummer::
BOSSBS-8021R
Beschreibung:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants containing different 5' UTRs, but encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BNUM0307-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0307-50
Lokale Artikelnummer::
BTIUBNUM0307-50
Beschreibung:
Reacts with human CD48, a 45 kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-2367R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2367R-CY3
Lokale Artikelnummer::
BOSSBS-2367R-CY3
Beschreibung:
A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system (CNS). It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorilation and synaptic function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8327R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8327R-CY7
Lokale Artikelnummer::
BOSSBS-8327R-CY7
Beschreibung:
Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12191R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12191R
Lokale Artikelnummer::
BOSSBS-12191R
Beschreibung:
DZIP3 is a 1,208 amino acid protein that localizes to the cytoplasm and contains one RING-type zinc finger. Expressed in a variety of tissues with highest expression in heart, skeletal muscle and kidney, DZIP3 functions as an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme, thereby playing a role in signaling events throughout the cell. Multiple isoforms of DZIP3 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11408R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11408R-CY3
Lokale Artikelnummer::
BOSSBS-11408R-CY3
Beschreibung:
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11408R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11408R-CY5
Lokale Artikelnummer::
BOSSBS-11408R-CY5
Beschreibung:
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15199R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15199R
Lokale Artikelnummer::
BOSSBS-15199R
Beschreibung:
C5orf20 is a intronless gene is specifically expressed in dendritic cells (DCs), which are potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response. The encoded protein is localized mainly in the perinucleus. One of the alleles (A/T) of this gene, that causes premature translation termination at aa 117, has been associated with an increased prevalence of major depression in humans
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11408R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11408R-A647
Lokale Artikelnummer::
BOSSBS-11408R-A647
Beschreibung:
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11408R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11408R-A488
Lokale Artikelnummer::
BOSSBS-11408R-A488
Beschreibung:
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1711R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1711R-A647
Lokale Artikelnummer::
BOSSBS-1711R-A647
Beschreibung:
PCDHA6 (Protocadherin alpha 6) is a member of the protocadherin family, a subgroup of the cadherin superfamily. Protocadherins are neural cadherin-like cell adhesion proteins that are integral membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific neuronal connections in the brain. PCDHA6 is one of fifteen tandemly arranged genes within the alpha cluster of protocadherin genes on 5q31.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11408R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11408R-A750
Lokale Artikelnummer::
BOSSBS-11408R-A750
Beschreibung:
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6938R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6938R-A555
Lokale Artikelnummer::
BOSSBS-6938R-A555
Beschreibung:
Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is the one EBV antigen that is expressed in all EBV associated malignancies. It has long been thought to go undetected by the cell mediated immune system. However, recent studies show that EBNA1 can be presented to both CD4+ and CD8+ T cells, making it a potential new target for immunotherapy of EBV related cancers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1711R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1711R-A750
Lokale Artikelnummer::
BOSSBS-1711R-A750
Beschreibung:
PCDHA6 (Protocadherin alpha 6) is a member of the protocadherin family, a subgroup of the cadherin superfamily. Protocadherins are neural cadherin-like cell adhesion proteins that are integral membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific neuronal connections in the brain. PCDHA6 is one of fifteen tandemly arranged genes within the alpha cluster of protocadherin genes on 5q31.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11652R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11652R
Lokale Artikelnummer::
BOSSBS-11652R
Beschreibung:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13545R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13545R-A647
Lokale Artikelnummer::
BOSSBS-13545R-A647
Beschreibung:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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