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Potassium+2-(trifluoromethyl)phenyltrifluoroborate
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Potassium+2-(trifluoromethyl)phenyltrifluoroborate
Artikel-Nr:
(BOSSBS-7862R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7862R-A488
Lokale Artikelnummer::
BOSSBS-7862R-A488
Beschreibung:
ILEI is a 227 amino acid, ubiquitously expressed protein containing an amino-terminal signal peptide. Elevated levels of ILEI translation are observed in oncogenic, Ras-transformed mammary epithelial cells and epithelial to mesenchymal transition (Emt) as well as tumor growth and metastasis. Also, overexpression of ILEI results in loss of ZO-1, a protein involved in tight junctions, and expression of cytoplasmic E-cadherin, which has been shown to influence loss of polarity and invasiveness. Due to this evidence, it is suspected that ILEI cooperates with oncogenic Ras to cause TGF∫-independent Emt and its overexpression is correlated with the invasion, metastasis and survival in a variety of cancers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7862R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7862R-A647
Lokale Artikelnummer::
BOSSBS-7862R-A647
Beschreibung:
ILEI is a 227 amino acid, ubiquitously expressed protein containing an amino-terminal signal peptide. Elevated levels of ILEI translation are observed in oncogenic, Ras-transformed mammary epithelial cells and epithelial to mesenchymal transition (Emt) as well as tumor growth and metastasis. Also, overexpression of ILEI results in loss of ZO-1, a protein involved in tight junctions, and expression of cytoplasmic E-cadherin, which has been shown to influence loss of polarity and invasiveness. Due to this evidence, it is suspected that ILEI cooperates with oncogenic Ras to cause TGF∫-independent Emt and its overexpression is correlated with the invasion, metastasis and survival in a variety of cancers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13513R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13513R-CY3
Lokale Artikelnummer::
BOSSBS-13513R-CY3
Beschreibung:
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR110 (G protein-coupled receptor 110), also known as PGR19, is a 911 amino acid protein that belongs to the G-protein coupled receptor 2 family and LN-TM7 subfamily. Characterized as an adhesion GPCR, GPR110 is a multipass membrane-bound protein with a long amino-terminus that contains multiple domains. One of these domains is the GPCR proteolytic site (GPS), which is essential for proteolytic cleavage of the amino-terminus and for cell surface expression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12315R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12315R-CY5
Lokale Artikelnummer::
BOSSBS-12315R-CY5
Beschreibung:
GUP1 is a 504 amino acid multipass membrane protein of the endoplasmic reticulum that functions as a membrane bound O-acyltransferase. With specific expression in heart, GUP1 negatively regulates amino-terminal palmitoylation of Shh by HHAT, a protein that is required for Shh signaling. Deletion of the gene encoding GUP1 results in higher sensibility to specific sphinogolipid biosynthesis inhibitors and resistance to ergosterol biosynthesis inhibitors, indicating that GUP1 is an essential component in lipid metabolism. Also, GUP1 also seems to be important for cell wall assembly and stability due to evidence in Saccharomyces cerevisiae GUP1 mutants, which exhibit altered plasma membrane lipid composition and membrane potential.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12315R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12315R-CY3
Lokale Artikelnummer::
BOSSBS-12315R-CY3
Beschreibung:
GUP1 is a 504 amino acid multipass membrane protein of the endoplasmic reticulum that functions as a membrane bound O-acyltransferase. With specific expression in heart, GUP1 negatively regulates amino-terminal palmitoylation of Shh by HHAT, a protein that is required for Shh signaling. Deletion of the gene encoding GUP1 results in higher sensibility to specific sphinogolipid biosynthesis inhibitors and resistance to ergosterol biosynthesis inhibitors, indicating that GUP1 is an essential component in lipid metabolism. Also, GUP1 also seems to be important for cell wall assembly and stability due to evidence in Saccharomyces cerevisiae GUP1 mutants, which exhibit altered plasma membrane lipid composition and membrane potential.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12315R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12315R-A555
Lokale Artikelnummer::
BOSSBS-12315R-A555
Beschreibung:
GUP1 is a 504 amino acid multipass membrane protein of the endoplasmic reticulum that functions as a membrane bound O-acyltransferase. With specific expression in heart, GUP1 negatively regulates amino-terminal palmitoylation of Shh by HHAT, a protein that is required for Shh signaling. Deletion of the gene encoding GUP1 results in higher sensibility to specific sphinogolipid biosynthesis inhibitors and resistance to ergosterol biosynthesis inhibitors, indicating that GUP1 is an essential component in lipid metabolism. Also, GUP1 also seems to be important for cell wall assembly and stability due to evidence in Saccharomyces cerevisiae GUP1 mutants, which exhibit altered plasma membrane lipid composition and membrane potential.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8163R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8163R-HRP
Lokale Artikelnummer::
BOSSBS-8163R-HRP
Beschreibung:
WDR79 contains six WD (tryptophan-aspartate) repeat domains found in a number of proteins that function as adaptor molecules in signal transduction and cytoskeletal organization. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. The function of the WDR79 protein has not been characterized, however significant and consistent single nucleotide polymorphisms in the WDR79 gene have been found to be associated with ER negative breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13312R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13312R-HRP
Lokale Artikelnummer::
BOSSBS-13312R-HRP
Beschreibung:
GCDH is a 438 amino acid protein that localizes to the mitochondrial matrix and belongs to the acyl-CoA dehydrogenase family. Existing as a homotetramer, GCDH uses FAD as a cofactor to catalyze the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine and L-tryptophan metabolism. While GCDH exists as both a long and short isoform, only the long isoform is a functionally active protein. Defects in the gene encoding GCDH are the cause of glutaric acidemia type I (GA-I), an autosomal recessive disorder that is characterized by the accumulation of glutaconic acid and is associated with such symptoms as progressive dystonia and athetosis due to gliosis and neuronal loss in the basal ganglia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8163R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8163R-A750
Lokale Artikelnummer::
BOSSBS-8163R-A750
Beschreibung:
WDR79 contains six WD (tryptophan-aspartate) repeat domains found in a number of proteins that function as adaptor molecules in signal transduction and cytoskeletal organization. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. The function of the WDR79 protein has not been characterized, however significant and consistent single nucleotide polymorphisms in the WDR79 gene have been found to be associated with ER negative breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8163R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8163R
Lokale Artikelnummer::
BOSSBS-8163R
Beschreibung:
WDR79 contains six WD (tryptophan-aspartate) repeat domains found in a number of proteins that function as adaptor molecules in signal transduction and cytoskeletal organization. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. The function of the WDR79 protein has not been characterized, however significant and consistent single nucleotide polymorphisms in the WDR79 gene have been found to be associated with ER negative breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11388R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11388R-HRP
Lokale Artikelnummer::
BOSSBS-11388R-HRP
Beschreibung:
AAMP is a 434 amino acid immunoglobulin-like protein that contains 8 WD repeats. Expressed in endothelial cells, cytotrophoblasts and blood vessels, AAMP is thought to have a heparin-sensitive role in cell adhesion and cell migration. AAMP is strongly expressed in poorly differentiated colon adenocarcinoma cells, suggesting a role for AAMP in tumor progression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7969R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7969R-A647
Lokale Artikelnummer::
BOSSBS-7969R-A647
Beschreibung:
ARMC3 contains 12 ARM repeats. ARM (Armadillo/beta-catenin-like) domains are imperfect 45-amino acid repeats involved in protein-protein interactions. ARM domain-containing proteins, such as ARMC3, function in signal transduction, development, cell adhesion and mobility, and tumor initiation and metastasis. The specific function of ARMC3 is not yet known.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9616R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9616R-A647
Lokale Artikelnummer::
BOSSBS-9616R-A647
Beschreibung:
Ubr7 is a 425 amino acid protein that contains one UBR-type zinc finger and one PHD zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr7 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12462R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12462R-CY5
Lokale Artikelnummer::
BOSSBS-12462R-CY5
Beschreibung:
AGPS is a 658 amino acid enzyme that is required for glycerolipid metabolism and ether lipid biosynthesis. Localized to the inner aspect of the peroxisomal membrane, AGPS is likely part of a heterotrimeric complex that is also composed of GNPAT and a modified form of GNPAT. Containing one FAD-binding PCMH-type domain, AGPS utilizes FAD as a cofactor in the synthesis of alkyl-glycerone 3-phophate and a long-chain acid anion from 1-acteyl-glyerone 3-phosphate and a long-chain alcohol. Defects in the gene encoding AGPS results in rhizomelic chondrodysplasia punctata type 3, a disease characterized by vertebral disorders, severe mental retardation, cutaneous lesions, cataracts and rhizomelic shortening of the humerus and femur.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1603R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1603R-A488
Lokale Artikelnummer::
BOSSBS-1603R-A488
Beschreibung:
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9089R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9089R-A647
Lokale Artikelnummer::
BOSSBS-9089R-A647
Beschreibung:
Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin (CUL1), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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