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Sodium+sulphite
Lieferant:
Biotium
Beschreibung:
This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
Lieferant:
Biotium
Beschreibung:
This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
Artikel-Nr:
(BOSSBS-12260R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12260R
Lokale Artikelnummer::
BOSSBS-12260R
Beschreibung:
The proteasome represents a large protein complex that exists inside all eukaryotes and archaea, and in some bacteria. The main function of proteasomes is to degrade unnecessary or damaged proteins by proteolysis. The most common form of the proteasome, known as the 26S Proteasome, contains one 20S Proteasome core particle structure and two 19S regulatory caps. The 20S Proteasome core is hollow and forms an enclosed cavity, where proteins are degraded, as well as openings at the two ends to allow the target protein to enter. The 20S Proteasome core particle contains many subunits, depending on the organism. All of the subunits fall into one of two types: alpha subunits, which are structural, serve as docking domains for the regulatory particles and exterior gates blocking unregulated access to the interior cavity; or beta subunits, which are predominantly catalytic. The outer two rings in the proteasome consist of seven ?subunits each, and the inner two rings each consist of seven beta subunits.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11776R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11776R-CY5
Lokale Artikelnummer::
BOSSBS-11776R-CY5
Beschreibung:
E6-associating protein is a component of the ubiquitin-mediated proteolytic pathway, which selectively targets proteins for degradation by the 26S proteasome. Ubiquitin (Ub) is directly conjugated to protein substrates by the transfer of Ub from an E2 ubiquitin conjugating enzyme to the target protein. This conjugation is facilitated by the enzymatic activity of E3 ubiquitin ligase family members such as E6-AP. Several substrates of E6-AP have been identified and include the tumor suppressor protein p53 and the mammalian homolog of Rad23, HHR23A. Previous studies have indicated that E6-AP associates with the human papillomavirus E6 oncogene, which complexes with p53 and thereby potentiates E6-AP mediated ubiquitination of p53. Genetic mutations that impair E6-AP activity result in the accumulation of p53 in the cytoplasm, and, in many instances, these mutations are associated with the development of the rare neurodevelopmental disorder Angelman syndrome (AS), which is characterized by severe motor dysfunction and mental retardation.
VE:
1 * 100 µl
Artikel-Nr:
(EHERXA12733000ME)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
XA12733000ME
Lokale Artikelnummer::
EHERXA12733000ME
Beschreibung:
Organic Standard, 2,6-Xylenol 100 µg/ml in Methanol, Packung: Glasflasche
VE:
1 * 1 mL
Lieferant:
Cytiva
Beschreibung:
Hilfssiebe für XK 26 und AK 26
Lieferant:
Liebherr
Beschreibung:
Kühlschränke für den professionellen Gebrauch. Temperatur-unempfindliche Produkte auch bei Umgebungstemperaturen bis +40 °C bei konstanter Kühlleistung zuverlässig lagern. Sie sind enorm robust, langlebig, pflegeleicht und besonders nachhaltig, nicht nur dank natürlichem Kältemittel. Gleichzeitig erfüllen sie alle gültigen Richtlinien, Standards und Normen, auch in puncto Hygiene und HACCP-Konzept. Das effiziente Kühlsystem sorgt nicht nur für niedrige Energie- und Gesamtbetriebskosten, sondern auch für eine sichere Lagerung ohne Anforderung an Validierung von Temperatur-Stabilität und Homogenität.
Artikel-Nr:
(ABCRAB142608.0500)
Lieferant:
ABCR
Hersteller-Artikelnummer::
AB142608.0500
Lokale Artikelnummer::
ABCRAB142608.0500
Beschreibung:
Toluendiisocyanat ≥99% (2,4-80%, 2,6-20%)
VE:
1 * 500 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
JULABO GmbH
Beschreibung:
Kalibrier-Thermostate sind für Anwendungen in Kalibrierlaboren, wie z. B. ISO, DKD, NAMAS, UKAS, und für Anforderungen gemäß DIN EN ISO 9001:2000 vorgesehen. Die Einheiten verfügen über eine Kammer mit konstanter Temperatur und eignen sich zur präzisen Kalibrierung von Temperatursensoren, Messgeräten und Thermometern gemäß nationaler und internationaler Standards. Die Modelle mit Kältemaschine eignen sich für alle Temperaturen von –30 bis +200 °C sowie als Kalibrier-Thermostate für Temperaturen von 50 bis 300 °C. Der optionale Präzisions-Referenzsensor ermöglicht das Messen von Referenztemperaturen. Die Bäder sind mit einer PID-Kaskaden-Temperaturregelung für höchste interne und externe Temperaturkonstanz und einem integrierten Programmgeber für 10 Programmschritte ausgestattet.
Artikel-Nr:
(1.01031.0500)
Lieferant:
Merck
Hersteller-Artikelnummer::
1.01031.0500
Lokale Artikelnummer::
MERC1.01031.0500
Beschreibung:
Aluminiumammoniumsulfat Dodecahydrat, EMSURE® zur Analyse, Supelco®
VE:
1 * 500 g
Lieferant:
VWR Chemicals
Beschreibung:
Aluminiumammoniumsulfat Dodecahydrat ≥98%, GPR RECTAPUR®
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 80 kDa-90 kDa, identified as CD36 (Workshop IV; Code P-26). Its epitope maps between aa155-183. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36. This MAb blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation.
Artikel-Nr:
(BOSSBS-11776R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11776R-FITC
Lokale Artikelnummer::
BOSSBS-11776R-FITC
Beschreibung:
E6-associating protein is a component of the ubiquitin-mediated proteolytic pathway, which selectively targets proteins for degradation by the 26S proteasome. Ubiquitin (Ub) is directly conjugated to protein substrates by the transfer of Ub from an E2 ubiquitin conjugating enzyme to the target protein. This conjugation is facilitated by the enzymatic activity of E3 ubiquitin ligase family members such as E6-AP. Several substrates of E6-AP have been identified and include the tumor suppressor protein p53 and the mammalian homolog of Rad23, HHR23A. Previous studies have indicated that E6-AP associates with the human papillomavirus E6 oncogene, which complexes with p53 and thereby potentiates E6-AP mediated ubiquitination of p53. Genetic mutations that impair E6-AP activity result in the accumulation of p53 in the cytoplasm, and, in many instances, these mutations are associated with the development of the rare neurodevelopmental disorder Angelman syndrome (AS), which is characterized by severe motor dysfunction and mental retardation.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 80 kDa-90 kDa, identified as CD36 (Workshop IV; Code P-26). Its epitope maps between aa155-183. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36. This MAb blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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