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17-Octadecinsäure
Artikel-Nr:
(BOSSBS-5141R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5141R-A350
Lokale Artikelnummer::
BOSSBS-5141R-A350
Beschreibung:
Matrin 3 (MATR 3) is an internal nuclear matrix protein that may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer MATR 3 may play a role in nuclear retention of defective RNAs. MATR3 forms part of complex consisting of SFPQ, NONO and MATR3.The protein contains 1 matrin type zinc finger and 2 RRM (RNA recognition motif) domains. Two transcript variants encoding the same protein have been identified for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5974R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5974R-A680
Lokale Artikelnummer::
BOSSBS-5974R-A680
Beschreibung:
SMYD3 is a gene that is over-expressed in the majority of colorectal carcinomas and hepatocellular carcinomas. SMYD3 forms a complex with RNA polymerase II through an interaction with the RNA helicase HELZ and transactivates a set of genes that included oncogenes, homeobox genes and genes associated with cell-cycle regulation. SMYD3 binds to a motif, 5'-CCCTCC-3', present in the promoter region of downstream genes such as Nkx2.8. The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, which is enhanced in the presence of the heat-shock protein HSP90A.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6673R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6673R-FITC
Lokale Artikelnummer::
BOSSBS-6673R-FITC
Beschreibung:
KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1720R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1720R-A750
Lokale Artikelnummer::
BOSSBS-1720R-A750
Beschreibung:
Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6673R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6673R-CY5.5
Lokale Artikelnummer::
BOSSBS-6673R-CY5.5
Beschreibung:
KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5660R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5660R-HRP
Lokale Artikelnummer::
BOSSBS-5660R-HRP
Beschreibung:
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4982R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4982R-CY7
Lokale Artikelnummer::
BOSSBS-4982R-CY7
Beschreibung:
HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. HIV1 Gag p17, the HIV1 matrix protein is produced by the digestion of its precursor Gag p55 by HIV1 protease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5141R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5141R-A488
Lokale Artikelnummer::
BOSSBS-5141R-A488
Beschreibung:
Matrin 3 (MATR 3) is an internal nuclear matrix protein that may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer MATR 3 may play a role in nuclear retention of defective RNAs. MATR3 forms part of complex consisting of SFPQ, NONO and MATR3.The protein contains 1 matrin type zinc finger and 2 RRM (RNA recognition motif) domains. Two transcript variants encoding the same protein have been identified for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3521R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3521R-FITC
Lokale Artikelnummer::
BOSSBS-3521R-FITC
Beschreibung:
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8356R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8356R-A555
Lokale Artikelnummer::
BOSSBS-8356R-A555
Beschreibung:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of CHIP, TRAF6 and TRIM63/MURF1. Ubiquitinates CHIP-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3428R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3428R-A488
Lokale Artikelnummer::
BOSSBS-3428R-A488
Beschreibung:
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5661R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5661R-A488
Lokale Artikelnummer::
BOSSBS-5661R-A488
Beschreibung:
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5974R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5974R
Lokale Artikelnummer::
BOSSBS-5974R
Beschreibung:
SMYD3 is a gene that is over-expressed in the majority of colorectal carcinomas and hepatocellular carcinomas. SMYD3 forms a complex with RNA polymerase II through an interaction with the RNA helicase HELZ and transactivates a set of genes that included oncogenes, homeobox genes and genes associated with cell-cycle regulation. SMYD3 binds to a motif, 5'-CCCTCC-3', present in the promoter region of downstream genes such as Nkx2.8. The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, which is enhanced in the presence of the heat-shock protein HSP90A.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8356R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8356R-A350
Lokale Artikelnummer::
BOSSBS-8356R-A350
Beschreibung:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of CHIP, TRAF6 and TRIM63/MURF1. Ubiquitinates CHIP-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3428R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3428R-A647
Lokale Artikelnummer::
BOSSBS-3428R-A647
Beschreibung:
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8356R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8356R-A750
Lokale Artikelnummer::
BOSSBS-8356R-A750
Beschreibung:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. <i>in vitro</i> catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of CHIP, TRAF6 and TRIM63/MURF1. Ubiquitinates CHIP-associated HSP90AB1 <i>in vitro</i>. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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