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1-Boc-3-indolboronsäurepinakolester
Artikel-Nr:
(ABNOMAB15290)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB15290
Lokale Artikelnummer::
ABNOMAB15290
Beschreibung:
Mouse monoclonal antibody raised against human TFRC.
VE:
1 * 100 Assays
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-CD100 (SEMA4D) Rat Monoclonal Antibody [clone: BMA-12] (PE (Phycoerythrin))
Lieferant:
MACHEREY-NAGEL
Beschreibung:
CHROMABOND® Vacuum manifolds are designed for reproducible SPE applications.
Lieferant:
Sigma-Aldrich
Beschreibung:
N,N,N',N'-Tetramethylethylendiamin (TEMED), Sigma-Aldrich®
Artikel-Nr:
(442-0855)
Lieferant:
ASYNT
Hersteller-Artikelnummer::
ADS5-S
Lokale Artikelnummer::
ASYNADS5-S
Beschreibung:
DrySyn Multi-M Super-Kit, Basisplatte, mit 12 Kolbeneinsätzen (3×50 ml, 3×100 ml und 3×250 ml)
VE:
1 * 1 ST
Artikel-Nr:
(DELT19906)
Lieferant:
DELTALAB
Hersteller-Artikelnummer::
19906
Lokale Artikelnummer::
DELT19906
Beschreibung:
HDPE, white.
VE:
1 * 1 ST
Artikel-Nr:
(735-0223)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
150200
Lokale Artikelnummer::
NUNC150200
Beschreibung:
PS, non treated, with lid, sterile.
VE:
1 * 75 ST
Lieferant:
Heidolph Instruments GmbH & Co.KG
Beschreibung:
Mehrkanal-Pumpenköpfe, Modelle C4, C8 und C12. Kann über das Mehrkanaladapter mit Dispensierpumpenantrieben PD 5001, PD 5101, und PD 5201 betrieben werden. Bis zu 12 Pumpenkanäle können simultan betrieben werden. Separate Dosierung in verschiedene Behälter in einem Arbeitsgang.
Lieferant:
DELTALAB
Beschreibung:
PP, square with translucent lid.
Lieferant:
KOEHLER TECHNISCHE PRODUKTEN
Beschreibung:
Made of acrylic, clear.
Artikel-Nr:
(BOCH5060)
Lieferant:
BOCHEM
Hersteller-Artikelnummer::
5060
Lokale Artikelnummer::
BOCH5060
Beschreibung:
Tempered cast iron, green varnished.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-13140R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13140R-A488
Lokale Artikelnummer::
BOSSBS-13140R-A488
Beschreibung:
Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromsomal instability (1,2). The FA Group C complementation group gene encodes the protein FANCC, which is located in both cytoplasmic and nuclear compartments. FANCC is expressed in a cell cycle-dependent manner, with the lowest levels at the G1/S boundary and the highest levels in the M-phase. The FANCC protein interacts with other FA complementation group proteins as well as non-FA proteins (3). A human a spectrin II (designated aSpIIs) acts as a scaffold to enhance interactions between FANCC and FANCA to form a nuclear complex (4,5). Another binding partner of FANCC is the BTB/POZ domain containing protein FAZF, which is a transcriptional repressor (6). In hematopoietic cells expressing mutant FANCC, PKR is constitutively phosphorylated and has increased binding affinity for double-stranded RNA (7,8), which suggests that FANCC indirectly suppresses the activity of PKR. These cells are also apoptotic and are hypersensitive to IFNg and TNFa (8). In addition, FANCC protein is involved in the activation of STAT1 through receptors for at least three hematopoietic growth and survival factors (8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11607R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11607R-A680
Lokale Artikelnummer::
BOSSBS-11607R-A680
Beschreibung:
The leucine-rich (LRR) repeat is a 20 to 30 amino acid motif that forms a hydrophobic / horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRC54 (leucine-rich repeat-containing protein 54), also known as tsukushin, TSKU or E2-induced gene 4 protein (E2IG4), is a 353 amino acid secreted protein that likely localizes to the cell membrane and extracellular compartments. Involved in extracellular secretion and intracellular transport, LRRC54 can be induced by 17-beta-estradiol. Containing nine LRR repeat and a cleavable signal peptide, the gene encoding LRRC54 maps to human chromosome 11, which houses over 1400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13140R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13140R-A647
Lokale Artikelnummer::
BOSSBS-13140R-A647
Beschreibung:
Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromsomal instability (1,2). The FA Group C complementation group gene encodes the protein FANCC, which is located in both cytoplasmic and nuclear compartments. FANCC is expressed in a cell cycle-dependent manner, with the lowest levels at the G1/S boundary and the highest levels in the M-phase. The FANCC protein interacts with other FA complementation group proteins as well as non-FA proteins (3). A human a spectrin II (designated aSpIIs) acts as a scaffold to enhance interactions between FANCC and FANCA to form a nuclear complex (4,5). Another binding partner of FANCC is the BTB/POZ domain containing protein FAZF, which is a transcriptional repressor (6). In hematopoietic cells expressing mutant FANCC, PKR is constitutively phosphorylated and has increased binding affinity for double-stranded RNA (7,8), which suggests that FANCC indirectly suppresses the activity of PKR. These cells are also apoptotic and are hypersensitive to IFNg and TNFa (8). In addition, FANCC protein is involved in the activation of STAT1 through receptors for at least three hematopoietic growth and survival factors (8).
VE:
1 * 100 µl
Lieferant:
Avantor Fluid Handling
Beschreibung:
Ideal for most acid/base or ionic salt applications.
Artikel-Nr:
(BOSSBS-9461R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9461R-A488
Lokale Artikelnummer::
BOSSBS-9461R-A488
Beschreibung:
The LIN-12/Notch family of transmembrane receptors plays a central role in development by regulating cell fate and establishing boundaries of gene expression. Notch signaling activates the Hairy/Enhancer of split (HES) genes, which encode basic helix-loop-helix (bHLH) transcriptional repressors that are critical for directing embryonic patterning and development. The Hairy-related transcription factors (HRTs) comprise a subclass of bHLH proteins that exhibit structural similarity with the HES proteins and include HRT1, HRT2 and HRT3. The HRT family (also designated Hesr, Hey, CHF and Gridlock) contain a bHLH domain, an Orange domain and a novel YRPW domain, which is absent in HRT3. The Hairy-related genes map to human chromosomes 8q21, 6q21 and 1p34.3 for HRT1, HRT2 and HRT3, respectively, and are downstream targets for Notch signaling. HRT1 is expressed in the somitic mesoderm, central nervous system, kidney, heart, nasal epithelium and limb buds in murine embryos as well as in adult tissues. It has altered expression in many breast, lung and kidney tumors. Like HRT1, HRT2 and HRT3 are also expressed in developing somites, heart and nervous system.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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