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1H-Imidazol-2-ylmethanol
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1H-Imidazol-2-ylmethanol
Artikel-Nr:
(BOSSBS-9047R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9047R-A680
Lokale Artikelnummer::
BOSSBS-9047R-A680
Beschreibung:
Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarisation and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid <i>in vitro</i>. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
VE:
1 * 100 µl
Artikel-Nr:
(WHEA216017)
Lieferant:
DWK Life Sciences
Hersteller-Artikelnummer::
216017
Lokale Artikelnummer::
WHEA216017
Beschreibung:
Flasche und Stopfen aus Borosilikatglas.
VE:
1 * 10 ST
Artikel-Nr:
(BOSSBS-9067R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-CY5.5
Lokale Artikelnummer::
BOSSBS-9067R-CY5.5
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-A647
Lokale Artikelnummer::
BOSSBS-9067R-A647
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(MFLX06043-93)
Lieferant:
Avantor Fluid Handling
Hersteller-Artikelnummer::
06043-93
Lokale Artikelnummer::
MFLB06043-93
Beschreibung:
Ideal for contamination-free removal of organic solvents.
VE:
1 * 1 ST
Artikel-Nr:
(COBBOS-2093-25G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
OS-2093-25G
Lokale Artikelnummer::
COBBOS-2093-25G
Beschreibung:
4-Brom-2,6-difluorbenzonitril
VE:
1 * 25 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(MAYBBTB09774.1)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
BTB09774.1
Lokale Artikelnummer::
MAYBBTB09774.1
Beschreibung:
Bromcyclododecan
VE:
1 * 1 g
This is a MarketSource item. Additional charges may apply
Lieferant:
Bohlender
Beschreibung:
Micro stirrer shafts made of PTFE-jacketed stainless steel with blade made completely of PTFE. With four round paddles.
Lieferant:
FLUOROCHEM
Beschreibung:
2,3-Difluor-4-methylbenzamid
Artikel-Nr:
(BIBBCX5/25/SC)
Lieferant:
SciLabware
Hersteller-Artikelnummer::
CX5/25/SC
Lokale Artikelnummer::
BIBBCX5/25/SC
Beschreibung:
PYREX®, borosilicate glass.
VE:
1 * 2 ST
Lieferant:
Thermo Scientific
Beschreibung:
2-Brom-6-nitrotoluol
Lieferant:
Bernd Kraft
Beschreibung:
Bromkresolgrün 0,04% in wässriger Lösung
Lieferant:
CEMO
Beschreibung:
These small container/laboratory trays can be combined to cover a complete storage area and also can be used as storage/filling station. Trays can be used with or without perforated plate.
Artikel-Nr:
(AMARE920410)
Lieferant:
AMARELL, ARNO
Hersteller-Artikelnummer::
E920410
Lokale Artikelnummer::
AMARE920410
Beschreibung:
Quadruple count down/count up timer with loud alarm signal.
VE:
1 * 1 ST
Lieferant:
Sigma-Aldrich
Beschreibung:
Amphotericin B (aus Streptomyces species), Sigma-Aldrich®
Lieferant:
Thermo Scientific
Beschreibung:
2-Propylphenol
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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