3-Aminopiperidine+hydrochloride,+N1-CBZ+protected
Artikel-Nr:
(BOSSBS-12928R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12928R-CY7
Lokale Artikelnummer::
BOSSBS-12928R-CY7
Beschreibung:
The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP26A1 is a major retinoic acid catabolic enzyme. CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid. CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptor ∫2. Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, imperforate anus, agenesis of the caudal portions of the digestive and urogenital tracts, and malformed lumbosacral skeletal elements. CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, human FAP adenomas, human sporadic colon carcinomas, and in the intestine of adenomatous polyposis coli (apcmcr) mutant zebrafish embryos.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8333R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8333R-CY5
Lokale Artikelnummer::
BOSSBS-8333R-CY5
Beschreibung:
RDH13, also known as all-trans and 9-cis retinol dehydrogenase 13 or SDR7C3, is a 331 amino acid mitochondrial protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, mostly in eye, pancreas, placenta and lung, RDH13 localizes on the outer side of the inner mitochondrial membrane. Related to microsomal retinoid oxidoreductase RDH11, RDH13 is considered to be a major enzyme among the RDH family of proteins. Catalytically active, RDH13 recognizes retinoids as substrates and may function in retinoic acid production. RDH13 may function to protect the mitochondria against oxidative stress. Leber congenital amaurosis (LCA) type 3, an inherited autosomal recessive retinal disease, has been associated with defects of RDH13. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8333R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8333R-CY3
Lokale Artikelnummer::
BOSSBS-8333R-CY3
Beschreibung:
RDH13, also known as all-trans and 9-cis retinol dehydrogenase 13 or SDR7C3, is a 331 amino acid mitochondrial protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, mostly in eye, pancreas, placenta and lung, RDH13 localizes on the outer side of the inner mitochondrial membrane. Related to microsomal retinoid oxidoreductase RDH11, RDH13 is considered to be a major enzyme among the RDH family of proteins. Catalytically active, RDH13 recognizes retinoids as substrates and may function in retinoic acid production. RDH13 may function to protect the mitochondria against oxidative stress. Leber congenital amaurosis (LCA) type 3, an inherited autosomal recessive retinal disease, has been associated with defects of RDH13. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9095R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9095R-CY7
Lokale Artikelnummer::
BOSSBS-9095R-CY7
Beschreibung:
Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.
VE:
1 * 100 µl
Lieferant:
ELTEN
Beschreibung:
Sportlicher, leichter und lederfreier ESD-Schuh aus Mikrofaser mit Netzeinsätzen, gepolsterter Lasche und rutschfester Zweidichten-PU/PU-Laufsohle (Fun).
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Artikel-Nr:
(HONCR1056-10MG)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
R1056-10MG
Lokale Artikelnummer::
HONCR1056-10MG
Beschreibung:
Organic Standard, Detomidine hydrochloride monohydrate, Packung: Glass Bottle
VE:
1 * 10 mg
Artikel-Nr:
(EDQMA0360000)
Lieferant:
EDQM
Hersteller-Artikelnummer::
A0360000
Lokale Artikelnummer::
EDQMA0360000
Beschreibung:
Organic Standard, Alprenolol hydrochloride, Ph. Eur. standard, Packung: Vial
VE:
1 * 100 mg
Lieferant:
3M
Beschreibung:
Der SecureFit™ X5501V-CE Schutzhelm verfügt über ein einfach einzustellendes 4-Punkt-Ratschen-Aufhängungssystem mit der exklusiven 3M™ Pressure Diffusion Technology. Dieser randlose, weiße Schutzhelm verfügt über einen UVicator™-Sensor, der anzeigt, wenn der Schutzhelm übermäßiger UV-Strahlung ausgesetzt wurde und ersetzt werden muss.
Artikel-Nr:
(BSENS-073-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
S-073-100
Lokale Artikelnummer::
BSENS-073-100
Beschreibung:
FUNCTION: Involved in redox regulation of the cell. Can reduce hydrogen peroxide and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. SUBUNIT: Homotetramer. May interact with HTR2A. SUBCELLULAR LOCATION: Cytoplasm. Lysosome. Also found in lung secretory organelles. MISCELLANEOUS: The active site is the redox-active Cys-47 oxidized to Cys-SOH. Cys-SOH may rapidly react with a Cys-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin . MISCELLANEOUS: Irreversibly inactivated by overoxidation of Cys-47 (to Cys-SO(3)H) upon oxidative stress. SIMILARITY: Belongs to the ahpC/TSA family. Rehydrin subfamily.
VE:
1 * 100 µl
Artikel-Nr:
(PROOMM0609.07)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
MM0609.07
Lokale Artikelnummer::
PROOMM0609.07
Beschreibung:
Organic Standard, 5-(1-Methylpiperidin-4-yl)-5H-dibenzo[a,d][7]annulen-5-ol hydrochloride
VE:
1 * 50 mg
Lieferant:
Merck Millipore (Calbiochem)
Beschreibung:
Guanidiniumchlorid, Millipore®
Artikel-Nr:
(IKAA3326400)
Lieferant:
IKA
Hersteller-Artikelnummer::
3326400
Lokale Artikelnummer::
IKAA3326400
Beschreibung:
Splinter protection LR-2.SP, prevents potential injuries
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-7023R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7023R-A680
Lokale Artikelnummer::
BOSSBS-7023R-A680
Beschreibung:
Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs can activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they also increase the ability of uninfected host cells to resist new infection by virus. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes.
VE:
1 * 100 µl
Lieferant:
ENTEGRIS
Beschreibung:
Serie 182
Branchenübliche 150-mm-Prozesswafer-Träger. Vierpunktauflage auf dem „H“-Profil für verbesserte Wafer-Positionierung. Offenes Seitenwand-Design um Flüssigkeitsfallen zu verhindern und die gleichmäßige Bedeckung mit und den Ablauf von der Lösung zu begünstigen. Hohe Form für maximalen Schutz von Wafern.
Artikel-Nr:
(BOSSBS-13168R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13168R
Lokale Artikelnummer::
BOSSBS-13168R
Beschreibung:
Fc (Ig constant fragment) receptors ensure protection of the host against foreign antigens, such as microorganisms and pathogens, by removing Ig-coated antigen complexes from circulation. Fc receptors are present on lymphoid and myeloid derivatives, where they mediate endocytosis of Ig-antigen complexes, antibody production in B cells through T cell antigen presentation, cytotoxicity and the release of cytokines and reactive oxygen species. The Fc γ-binding protein (FCGBP) interacts with the Fc portion of IgG and MUC2 to mediate the maintenance of the mucosal structure. FCGBP is a 5,405 amino acid protein that contains twelve TIL (trypsin inhibitory-like) domains and thirteen VWFD domains. It is predominantly expressed in placenta and colon epithelium as well as in thyroid and serum. Patients with various autoimmune diseases seemingly have higher levels of FCGBP protein present in their serum.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9218R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9218R-A750
Lokale Artikelnummer::
BOSSBS-9218R-A750
Beschreibung:
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins(stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a type 2 salivary cysteine peptidase inhibitor. The protein is an S-type cystatin, based on its high level of expression in saliva, tears and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with a protective function.
VE:
1 * 100 µl
Preis auf Anfrage
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