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3-Ethoxy-2-thenoes\\\\u00E4ure
Artikel-Nr:
(BOSSBS-13147R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13147R-CY7
Lokale Artikelnummer::
BOSSBS-13147R-CY7
Beschreibung:
FNBP1 is a 617 amino acid protein that localizes to a variety of locations within the cell, including the cytoplasm, cytoskeleton, lysosome and the cell cortex, and contains one FCH domain, one REM repeat and one SH3 domain. Expressed at high levels in respiratory, reproductive and urinary systems, as well as in brown adipose tissue and epithelial cells of the gastrointestinal tract, FNBP1 interacts with Rho 7 and links the Actin cytoskeleton with Rho 7 signaling, playing a crucial role in membrane tubulation and cytoskeletal reorganization during endocytosis. Additionally, FNBP1, which exists as four alternatively spliced isoforms, enhances Actin polymerization and promotes membrane invagination and the formation of tubules. Chromosomal aberrations in the FNBP1 gene are associated with acute leukemias, suggesting a role for defective FNBP1 in carcinogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13147R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13147R-CY5
Lokale Artikelnummer::
BOSSBS-13147R-CY5
Beschreibung:
FNBP1 is a 617 amino acid protein that localizes to a variety of locations within the cell, including the cytoplasm, cytoskeleton, lysosome and the cell cortex, and contains one FCH domain, one REM repeat and one SH3 domain. Expressed at high levels in respiratory, reproductive and urinary systems, as well as in brown adipose tissue and epithelial cells of the gastrointestinal tract, FNBP1 interacts with Rho 7 and links the Actin cytoskeleton with Rho 7 signaling, playing a crucial role in membrane tubulation and cytoskeletal reorganization during endocytosis. Additionally, FNBP1, which exists as four alternatively spliced isoforms, enhances Actin polymerization and promotes membrane invagination and the formation of tubules. Chromosomal aberrations in the FNBP1 gene are associated with acute leukemias, suggesting a role for defective FNBP1 in carcinogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(MAYBGK02804.10)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
GK02804.10
Lokale Artikelnummer::
MAYBGK02804.10
Beschreibung:
3-Amino-1H-pyrazol-4-carbonsäure
VE:
1 * 10 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
FLUOROCHEM
Beschreibung:
2-Amino-4,4,4-trifluorbuttersäure
Artikel-Nr:
(BOSSBS-12317R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12317R
Lokale Artikelnummer::
BOSSBS-12317R
Beschreibung:
SCUBE3 is a novel secreted 993 amino acid cell-surface osteoblast protein that plays an important role in bone cell biology. While highly expressed in osteoblasts, SCUBE3 expression is unobservable or very low in non-bone tissues. SCUBE3 forms homo-oligomers and hetero-oligomers with SCUBE1, and may undergo C-terminal proteolytic cleavage or become N-glycosylated following translation. Two SCUBE3 isoforms exist as a result of alternative splicing events. SCUBE3 contains one CUB domain and nine EGF-like domains, and is encoded by a gene which maps to human chromosome 6p21.31, a region associated with a rare form of metabolic bone disease known as Paget's disease. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0076R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0076R
Lokale Artikelnummer::
BOSSBS-0076R
Beschreibung:
The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.
VE:
1 * 100 µl
Lieferant:
BIONET RESEARCH
Beschreibung:
3-Amino-3-(4-chlorphenyl)propionsäure
Artikel-Nr:
(BOSSBS-9454R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9454R-A680
Lokale Artikelnummer::
BOSSBS-9454R-A680
Beschreibung:
Acyl-coenzyme A synthetases (ACSs) are a large family of related enzymes known to catalyse the fundamental initial reaction in fatty acid metabolism. The ACS family is roughly characterised based on fatty acid chain length preference amongst different members. The nomenclature in the ACS family reflects this relationship and includes short-chain ACS (ACSS), medium-chain ACS (ACSM), long-chain ACS (ACSL) and very long-chain ACS (ACSVL). ACSVL family members are capable of activating both long (LCFAs) and very long-chain fatty acids (VLCFAs). There are six members of the human ACSVL subfamily, which have been described as solute carrier family 27A (SLC27A) gene products. They represent a group of evolutionarily conserved fatty acid transport proteins (FATPs) recognised for their role in facilitating translocation of long-chain fatty acids across the plasma membrane. The family nomenclature has recently been unified with their respective acyl-CoA synthetase family designations: ACSVL1 (FATP2), ACSVL2 (FATP6), ACSVL3 (FATP3), ACSVL4 (FATP1), ACSVL5 (FATP4) and ACSVL6 (FATP5). ACSVLs have unique expression patterns and are found in major organs of fatty acid metabolism, such as adipose tissue, liver, heart and kidney. ACSVL2 is a 619 amino acid multi-pass membrane protein. Encoded by a gene that maps to human chromosome 5q23.3, ACSVL2 may function as the predominant fatty acid protein transporter in heart.
VE:
1 * 100 µl
Artikel-Nr:
(COBBPN-8814-1G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
PN-8814-1G
Lokale Artikelnummer::
COBBPN-8814-1G
Beschreibung:
4-Amino-2-chlorphenylboronsäurepinakolester
VE:
1 * 1 g
This is a MarketSource item. Additional charges may apply
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Amino-m-toluylsäure
Artikel-Nr:
(BOSSBS-9635R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9635R-A555
Lokale Artikelnummer::
BOSSBS-9635R-A555
Beschreibung:
Zinc is an essential cofactor that is involved in cell growth and development, as well as in protein, nucleic acid and lipid metabolism. The transport of zinc across the cell membrane is crucial for correct enzyme and overall cell function. SLC39A11 (solute carrier family 39 (metal ion transporter), member 11), also known as ZIP11 (Zrt- and Irt-like protein 11), is a 342 amino acid multi-pass membrane protein belonging to the ZIP transporter family. Expressed as multiple alternatively spliced isoforms, SLC39A11 acts as a zinc-influx transporter and is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9635R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9635R-A350
Lokale Artikelnummer::
BOSSBS-9635R-A350
Beschreibung:
Zinc is an essential cofactor that is involved in cell growth and development, as well as in protein, nucleic acid and lipid metabolism. The transport of zinc across the cell membrane is crucial for correct enzyme and overall cell function. SLC39A11 (solute carrier family 39 (metal ion transporter), member 11), also known as ZIP11 (Zrt- and Irt-like protein 11), is a 342 amino acid multi-pass membrane protein belonging to the ZIP transporter family. Expressed as multiple alternatively spliced isoforms, SLC39A11 acts as a zinc-influx transporter and is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11172R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11172R-A680
Lokale Artikelnummer::
BOSSBS-11172R-A680
Beschreibung:
Proper nucleosome assembly is critical for compacting DNA into chromatin. In human and mouse there are 5 protein-coding genes which comprise the nucleosome assembly protein (NAP) family. NAP1L1 (NAP1) and NAP1L4 (NAP2) are ubiquitously expressed family members which have been the most extensively studied. The remaining three family members, NAP1L2, NAP1L3 and NAP1L5 are neuron-specific nucleosome assembly proteins translated from intronless genes which are monoallelically expressed. NAP1L2 (nucleosome assembly protein 1-like 2), also known as BPX (brain specific protein, X-linked), is a 460 amino acid protein containing acidic domains which are thought to mediate histone interactions. NAP1L2 binds to chromatin and interacts with Histones H3 and H4. The function of NAP1L2 is not clearly defined although evidence suggests that NAP1L2 influences histone acetylation and therefore may play a significant role in regulating transcription in developing neurons.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11172R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11172R-A350
Lokale Artikelnummer::
BOSSBS-11172R-A350
Beschreibung:
Proper nucleosome assembly is critical for compacting DNA into chromatin. In human and mouse there are 5 protein-coding genes which comprise the nucleosome assembly protein (NAP) family. NAP1L1 (NAP1) and NAP1L4 (NAP2) are ubiquitously expressed family members which have been the most extensively studied. The remaining three family members, NAP1L2, NAP1L3 and NAP1L5 are neuron-specific nucleosome assembly proteins translated from intronless genes which are monoallelically expressed. NAP1L2 (nucleosome assembly protein 1-like 2), also known as BPX (brain specific protein, X-linked), is a 460 amino acid protein containing acidic domains which are thought to mediate histone interactions. NAP1L2 binds to chromatin and interacts with Histones H3 and H4. The function of NAP1L2 is not clearly defined although evidence suggests that NAP1L2 influences histone acetylation and therefore may play a significant role in regulating transcription in developing neurons.
VE:
1 * 100 µl
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Amino-3-nitrophenylboronsäurepinakolester
Artikel-Nr:
(BOSSBS-12948R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12948R-FITC
Lokale Artikelnummer::
BOSSBS-12948R-FITC
Beschreibung:
CRTAC1 is a 661 amino acid secreted protein. CRTAC1 is O-glycosylated and contains one EGF-like domain and four FG-GAP repeats. Up-regulated in mesenchymal stem cells undergoing chondrogenic differentiation and also by growth factor BMP-4, CRTAC1 is found in the interterritorial matrix of articular deep zone cartilage. CRTAC1 is expressed as three isoforms produced by alternative splicing events. All isoforms are expressed in bone, cartilage and lung, while isoforms 1 and 2 are expressed in the brain. The gene that encodes CRTAC1 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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