3-Brom-2-fluor-5-methylphenylborons\u00E4ure
Artikel-Nr:
(BOSSBS-9338R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9338R-A555
Lokale Artikelnummer::
BOSSBS-9338R-A555
Beschreibung:
MARCH4, an E3 ubiquitin protein ligase, may mediate ubiquitination of MHC I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin protein ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1128R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1128R-A647
Lokale Artikelnummer::
BOSSBS-1128R-A647
Beschreibung:
Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2250R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2250R-A350
Lokale Artikelnummer::
BOSSBS-2250R-A350
Beschreibung:
The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3578R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3578R-A647
Lokale Artikelnummer::
BOSSBS-3578R-A647
Beschreibung:
TCTP is involved in calcium binding and microtubule stabilization. It is an immunoglobulin E dependent histamine-releasing factor produced by lymphocytes of atopic children and present in biologic fluids of allergic patients. Both human and mouse recombinant HRF proteins caused histamine release from human basophils of a subpopulation of donors (referenced from OMIM).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2766R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2766R-A488
Lokale Artikelnummer::
BOSSBS-2766R-A488
Beschreibung:
FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5403R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5403R-A555
Lokale Artikelnummer::
BOSSBS-5403R-A555
Beschreibung:
KCNC1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. It forms a heteromultimer with KCNG3, KCNG4 and KCNV2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7855R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7855R-A350
Lokale Artikelnummer::
BOSSBS-7855R-A350
Beschreibung:
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5142R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5142R-A488
Lokale Artikelnummer::
BOSSBS-5142R-A488
Beschreibung:
TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP free TAFII complex (TFTC). TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5718R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5718R-A555
Lokale Artikelnummer::
BOSSBS-5718R-A555
Beschreibung:
Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0118R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0118R-A680
Lokale Artikelnummer::
BOSSBS-0118R-A680
Beschreibung:
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2381R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2381R-A488
Lokale Artikelnummer::
BOSSBS-2381R-A488
Beschreibung:
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3137R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3137R-A647
Lokale Artikelnummer::
BOSSBS-3137R-A647
Beschreibung:
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3806R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3806R-A647
Lokale Artikelnummer::
BOSSBS-3806R-A647
Beschreibung:
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6846R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6846R-A350
Lokale Artikelnummer::
BOSSBS-6846R-A350
Beschreibung:
Nucleostemin is a protein found in the nucleoli of embryonic stem cells, adult CNS stem cells, primitive cells in the bone marrow and cancer cells. It is not in the differentiated cells of most adult tissues. It has been suggested to play a role in controlling the cell cycle progression in stem cells and cancer cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6159R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6159R-A647
Lokale Artikelnummer::
BOSSBS-6159R-A647
Beschreibung:
This gene encodes a member of a subfamily of Rho GTPase activating proteins that contain a steroidogenic acute regulatory protein related lipid transfer domain. The encoded protein localizes to focal adhesions and may be involved in regulating cell morphology. This protein may also function as a tumor suppressor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11999R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11999R-A488
Lokale Artikelnummer::
BOSSBS-11999R-A488
Beschreibung:
Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium.
VE:
1 * 100 µl
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