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1-Boc-3-indolboronsäurepinakolester
Artikel-Nr:
(PRSI48-422)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
48-422
Lokale Artikelnummer::
PRSI48-422
Beschreibung:
Prostaglandin E Receptor EP3 is a member of the Prostanoid Receptor subfamily. Along with several other receptor subtypes (EP1, EP2, and EP4), it mediates the diverse biological effects of Prostaglandin E2 (PGE2). PGE2 has been implicated in numerous processes, including immune response modulation, male erectile function, induction of labor, cervical cancer, control of blood pressure, and asthma. Various isoforms are produced by alternative splicing.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-513)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-513
Lokale Artikelnummer::
PRSI90-513
Beschreibung:
Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. Complex formation between IL-21R and the common gamma chain (gammac) is required for signalling. IL-21R is expressed mainly on B cells (highest on mature, activated, follicular and germinal center B cells), NK cells and activated T cells, but is also found on dendritic cells, alternatively activated macrophages, intestinal lamina propria fibroblasts and epithelial cells and keratinocytes. B cell IL-21R engagement induces Blimp1 (which mediates plasma cell differentiation) and is important for memory responses. IL-21R engagement on mouse NK cells enhances their cytotoxic activity and IFN-gamma production. IL-21R engagement on CD8+ T cells aids control of viral infection and tumour growth; IL-21R is also necessary for sufficient numbers of regulatory T cells to combat chronic inflammation. IL-21R expression is often upregulated in allergic skin inflammation, systemic lupus erythematosus and diffuse large B cell lymphoma (DLBCL).
VE:
1 * 25 µG
Artikel-Nr:
(PRSI27-130)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-130
Lokale Artikelnummer::
PRSI27-130
Beschreibung:
The PAX genes, including PAX1, are a highly conserved family of developmental control genes that encode transcription factors and have been shown to play a role in pattern formation during embryogenesis in vertebrates.The PAX genes, including PAX1, are a highly conserved family of developmental control genes that encode transcription factors and have been shown to play a role in pattern formation during embryogenesis in vertebrates (McGaughran et al., 2003 [PubMed 12774041]). See PAX7 (MIM 167410) for a discussion of paired box domain genes.
VE:
1 * 50 µG
Artikel-Nr:
(PRSIXP-5128)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XP-5128
Lokale Artikelnummer::
PRSIXP-5128
Beschreibung:
Exodus 2 is one of several CC cytokine genes clustered on the p arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterised by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI49-375)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
49-375
Lokale Artikelnummer::
PRSI49-375
Beschreibung:
Orexin, or hypocretin (HCRT), is a hypothalamic neuropeptide precusor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, are mediators in the central feedback mechanism that regulates feeding behavior.
VE:
1 * 50 µl
Artikel-Nr:
(PRSI31-154)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-154
Lokale Artikelnummer::
PRSI31-154
Beschreibung:
IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI36-145)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-145
Lokale Artikelnummer::
PRSI36-145
Beschreibung:
Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF-R signaling is essential for B cell development, survival and humoral immune responses.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-893)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-893
Lokale Artikelnummer::
PRSI25-893
Beschreibung:
SLC10A7 belongs to the sodium: bile acid symporter family. It is a multi-pass membrane protein. The function of SLC10A7 remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI28-325)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-325
Lokale Artikelnummer::
PRSI28-325
Beschreibung:
Extracellular HMGB1 is an activator of human tumor cell migration operating in concert with EGF. HMGB1 encodes a protein that is potentially involved in the regulation of lipogenic and cholesterogenic gene transcription.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI35-375)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
35-375
Lokale Artikelnummer::
PRSI35-375
Beschreibung:
Anti-Staphylococcus aureus Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 1 mL
Artikel-Nr:
(PRSI26-922)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-922
Lokale Artikelnummer::
PRSI26-922
Beschreibung:
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST1H1T is a member of the histone H1 family. Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI62-007)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-007
Lokale Artikelnummer::
PRSI62-007
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI91-122)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-122
Lokale Artikelnummer::
PRSI91-122
Beschreibung:
Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyses the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-331)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-331
Lokale Artikelnummer::
PRSI90-331
Beschreibung:
FGF-2 (Basic fibroblast growth factor) belongs to the FGF superfamily that is made up of 22 different fibroblast growth factor genes. FGF-2 and FGF-1 (acidic FGF) are unique in that they do not follow the conventional signal sequence for secretion. FGF-2 is found in five isoforms via alternative initiation of translation. Signalling of FGF-2 occurs through the high-affinity tyrosine kinase receptors FGFR1-4. FGF-2 is a potent wide-spectrum mitogen whose overexpression is associated with immortalisation and unregulated cell proliferation in many tumors. FGF-2 functions in angiogenesis, cell survival, tissue repair, embryonic development and inflammation. FGF-2 is widely used to maintain the self-renewal of human embryonic stem cells (ESCs) and to induce pluripotent stem cells. FGF-2 is an established neurogenic factor for proliferation and differentiation of multipotent neural stem cells both during development and in the adult mouse brain as well.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI31-092)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-092
Lokale Artikelnummer::
PRSI31-092
Beschreibung:
The CHRNA3 subunit is expressed in the soma of the majority of pyramidal cells, with the most alpha 3 immunoreactivity observed in CA2-4 and entorhinal cortex and relatively less in CA1 and subicular pyramidal cell soma.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7225)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7225
Lokale Artikelnummer::
PRSI7225
Beschreibung:
NELF Antibody: NELF (nasal embryonic luteinizing hormone-releasing hormone factor) is a 530 amino acid transcription factor involved in the migration of LHRH neurons, outgrowth of olfactory axons and suppression of transcription elongation. NELF is found in the peripheral and central nervous system during embryonic development, and is highly expressed in adult testis, kidney and brain. Known to couple NMDA receptor signaling to the nucleus, NELF knockdown impaired GnRH neuronal migration of NLT cells in vitro and the gene encoding NELF has been linked to the development of Idiopathic hypogonadotropic hypogonadism (IHH), a disorder resulting in impaired pubertal maturation and reproductive function.
VE:
1 * 100 µG
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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