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4-Amino-2-chloro-3-fluoropyridine
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4-Amino-2-chloro-3-fluoropyridine
Artikel-Nr:
(BOSSBS-3604R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3604R-FITC
Lokale Artikelnummer::
BOSSBS-3604R-FITC
Beschreibung:
WNK1 controls sodium and chloride ion transport by inhibiting the activity of WNK4, potentially by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide sensitive Na/Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11952R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11952R-A488
Lokale Artikelnummer::
BOSSBS-11952R-A488
Beschreibung:
The four isoforms of potassium/chloride co-transport channels (KCC) belong to a superfamily of cation-chloride co-transporters involved in cell volume maintenance. Nitric oxide (NO) donors activate KCCs, while inhibitors of the cGMP pathway prevent NO donor activation. The ubiquitously expressed KCC1 contains 12 transmembrane domains with both cytoplasmic N and C terminal domains. KCC2 expression is limited to neuronal tissues by a restrictive element similar to the neuronal-restrictive silencing factor. In neurons, KCC2 expression is correlated with an inhibitory response to GABA, while the absence of KCC2 is necessary for an unusual excitatory response to GABA. Alterations of KCC2 expression in the inferior colliculus of rat brain may be related to seizure susceptibility. Conversely, KCC3 is not suspected to play a major role in epilepsy. The two splice variants of KCC3, KCC3a and KCC3b, are predominantly expressed in brain and kidney, respectively, while KCC4 is expressed in muscle, brain, lung, heart and kidney.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
Phosphor(V)chlorid, Sigma-Aldrich®
Artikel-Nr:
(ABCRAB121254.0050)
Lieferant:
ABCR
Hersteller-Artikelnummer::
AB121254.0050
Lokale Artikelnummer::
ABCRAB121254.0050
Beschreibung:
Niob(V)chlorid ≥99% (Nb-Basis)
VE:
1 * 50 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
Alfa Aesar
Beschreibung:
Chelerythrine chloride ≥99%
Artikel-Nr:
(PRSI1401-7)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
1401-7
Lokale Artikelnummer::
PRSI1401-7
Beschreibung:
Herzgewebelysat (7 Tage alt) wurde durch Homogenisierung in modifiziertem RIPA-Puffer (150 mM Natriumchlorid, 50 mM Tris-HCl, pH 7,4, 1 mM Ethylendiamintetraessigsäure, 1 mM Phenylmethylsulfonylfluorid, 1% Triton X-100, 1% Natriumdesoxycholsäure, 0,1% Natriumdodecylsulfat, 5 μg/ml Aprotinin, 5 μg/ml Leupeptin) hergestellt.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI1403-0)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
1403-0
Lokale Artikelnummer::
PRSI1403-0
Beschreibung:
Hirngewebelysat (0 Tage alt) wurde durch Homogenisierung in modifiziertem RIPA-Puffer (150 mM Natriumchlorid, 50 mM Tris-HCl, pH 7,4, 1 mM Ethylendiamintetraessigsäure, 1 mM Phenylmethylsulfonylfluorid, 1% Triton X-100, 1% Natriumdesoxycholsäure, 0,1% Natriumdodecylsulfat, 5 μg/ml Aprotinin, 5 μg/ml Leupeptin) hergestellt.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI1402-7)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
1402-7
Lokale Artikelnummer::
PRSI1402-7
Beschreibung:
Lungengewebelysat (7 Tage alt) wurde durch Homogenisierung in modifiziertem RIPA-Puffer (150 mM Natriumchlorid, 50 mM Tris-HCl, pH 7,4, 1 mM Ethylendiamintetraessigsäure, 1 mM Phenylmethylsulfonylfluorid, 1% Triton X-100, 1% Natriumdesoxycholsäure, 0,1% Natriumdodecylsulfat, 5 μg/ml Aprotinin, 5 μg/ml Leupeptin) hergestellt.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(BOSSBS-1247R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1247R-CY7
Lokale Artikelnummer::
BOSSBS-1247R-CY7
Beschreibung:
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(CHMPFL5031.1)
Lieferant:
CHEMPUR
Hersteller-Artikelnummer::
FL5031.1
Lokale Artikelnummer::
CHMPFL5031.1
Beschreibung:
Phosphor(III)chlorid
VE:
1 * 1 kg
Artikel-Nr:
(BOSSBS-6981R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6981R-FITC
Lokale Artikelnummer::
BOSSBS-6981R-FITC
Beschreibung:
Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6981R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6981R-CY7
Lokale Artikelnummer::
BOSSBS-6981R-CY7
Beschreibung:
Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10307R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10307R-CY7
Lokale Artikelnummer::
BOSSBS-10307R-CY7
Beschreibung:
The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, 3q28, 4q32, Xp22.3, Xp11.23-p11.22, 1p36 and 16p13, respectively. CLC1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC2 is highly expressed in the epithelia of several organs including lung, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis. CLC3 expression is particularly abundant in neuronal tissue, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC5 lead to Dent’s disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC6 and CLC7 are broadly expressed in several tissues including testis, kidney, brain and muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10307R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10307R-FITC
Lokale Artikelnummer::
BOSSBS-10307R-FITC
Beschreibung:
The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, 3q28, 4q32, Xp22.3, Xp11.23-p11.22, 1p36 and 16p13, respectively. CLC1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC2 is highly expressed in the epithelia of several organs including lung, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis. CLC3 expression is particularly abundant in neuronal tissue, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC5 lead to Dent’s disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC6 and CLC7 are broadly expressed in several tissues including testis, kidney, brain and muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6981R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6981R-HRP
Lokale Artikelnummer::
BOSSBS-6981R-HRP
Beschreibung:
Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory.
VE:
1 * 100 µl
Lieferant:
Molecular Devices
Beschreibung:
The FLIPR® Potassium Assay Kit measures functional activity of ligand- and voltage-gated potassium channels. The homogeneous, no-wash assay protocol provides a large signal window and high Z' values.
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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