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3-Bromothiophene-4-sulphonyl+chloride


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Artikel-Nr: (BOSSBS-11040R-CY7)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-11040R-CY7
Lokale Artikelnummer:: BOSSBS-11040R-CY7
Beschreibung:   Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision. Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells. Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium. Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current. Bestrophin Bestrophin 2,Bestrophin 3, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels.
VE:  1 * 100 µl
Lieferant:  APPLICHEM
Beschreibung:   Kaliumchlorid 99,0-100,5 argentometric_dried USP, Ph. Eur., BP, pharma grade
Lieferant:  ABCR
Hersteller-Artikelnummer:: AB209725.0005
Lokale Artikelnummer:: ABCRAB209725.0005
Beschreibung:   trans-Bis(triphenylphosphin)palladium(II)chlorid ≥99,95% (Metall-Basis) Pd ≥ 14.7%, Premion®
VE:  1 * 5 g
Market Source Item This is a MarketSource item. Additional charges may apply
Lieferant:  CUSTOM MADE CHEMICALS LAB
Hersteller-Artikelnummer:: 3000600
Lokale Artikelnummer:: CMPL3000600
Beschreibung:   Bariumchlorid 0.1 mol/l (0.2 N) in wässriger Lösung Reag. Ph. Eur.
VE:  1 * 1 L
Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-7098R-HRP
Lokale Artikelnummer:: BOSSBS-7098R-HRP
Beschreibung:   Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis.Tissue specificity: Detected in epithelial cells from colon, esophagus and kidney (at protein level). Expression is prominent in heart, kidney, placenta and skeletal muscle.
VE:  1 * 100 µl
Lieferant:  MP Biomedicals
Beschreibung:   p-Iodonitrotetazolium Violet is used as a electron acceptor for the colorimetric assay of various dehydrogenases.
Lieferant:  Molekula
Hersteller-Artikelnummer:: M71641895
Lokale Artikelnummer:: MOLEM71641895
Beschreibung:   2-(4-Iodphenyl)-3-(4-nitrophenyl)-5-phenyltetrazoliumchlorid
VE:  1 * 5 g
Market Source Item This is a MarketSource item. Additional charges may apply

Lieferant:  Sigma-Aldrich
Hersteller-Artikelnummer:: 433780-1G
Lokale Artikelnummer:: SIAL433780-1G
Beschreibung:   1,3-Didecyl-2-methylimidazoliumchlorid, Sigma-Aldrich®
VE:  1 * 1 g

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-2927R-CY7
Lokale Artikelnummer:: BOSSBS-2927R-CY7
Beschreibung:   OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
VE:  1 * 100 µl
Artikel-Nr: (BOSSBS-2672R-CY3)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-2672R-CY3
Lokale Artikelnummer:: BOSSBS-2672R-CY3
Beschreibung:   The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
VE:  1 * 100 µl
Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-2672R-FITC
Lokale Artikelnummer:: BOSSBS-2672R-FITC
Beschreibung:   The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
VE:  1 * 100 µl
Artikel-Nr: (BOSSBS-2672R-CY5.5)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-2672R-CY5.5
Lokale Artikelnummer:: BOSSBS-2672R-CY5.5
Beschreibung:   The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-2927R-CY3
Lokale Artikelnummer:: BOSSBS-2927R-CY3
Beschreibung:   OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
VE:  1 * 100 µl
Lieferant:  Sigma-Aldrich
Beschreibung:   Bismut(III)chloridoxid, Sigma-Aldrich®
Artikel-Nr: (BOSSBS-9036R)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-9036R
Lokale Artikelnummer:: BOSSBS-9036R
Beschreibung:   A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.
VE:  1 * 100 µl
Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-2927R-FITC
Lokale Artikelnummer:: BOSSBS-2927R-FITC
Beschreibung:   OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
VE:  1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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