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Tris(pentafluorphenyl)boran
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Tris(pentafluorphenyl)boran
Artikel-Nr:
(BOSSBS-3237R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3237R-A350
Lokale Artikelnummer::
BOSSBS-3237R-A350
Beschreibung:
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. Negatively regulates the pathway by phosphorylating the scaffold protein TAXBP1 and thus promoting the assembly of the A20/TNFAIP3 ubiquitin-editing complex (composed of A20/TNFAIP3, TAX1BP1, and the E3 ligases ITCH and RNF11). Therefore, CHUK plays a key role in the negative feedback of NF-kappa-B canonical signaling to limit inflammatory gene activation. As part of the non-canonical pathway of NF-kappa-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. In turn, these complexes regulate genes encoding molecules involved in B-cell survival and lymphoid organogenesis. Participates also in the negative feedback of the non-canonical NF-kappa-B signaling pathway by phosphorylating and destabilizing MAP3K14/NIK. Within the nucleus, phosphorylates CREBBP and consequently increases both its transcriptional and histone acetyltransferase activities. Modulates chromatin accessibility at NF-kappa-B-responsive promoters by phosphorylating histones H3 at 'Ser-10' that are subsequently acetylated at 'Lys-14' by CREBBP. Additionally, phosphorylates the CREBBP-interacting protein NCOA3.
VE:
1 * 100 µl
Artikel-Nr:
(PRTWPA48BKR)
Lieferant:
Portwest Clothing
Hersteller-Artikelnummer::
PA48BKR
Lokale Artikelnummer::
PRTWPA48BKR
Beschreibung:
Four points chin strap suitable for Endurance helmets.
VE:
1 * 5 ST
Lieferant:
HONEYWELL SAFETY
Beschreibung:
Heavy duty air hoods range designed for use with powered air purifying respirator (PAPR) as Compact Air 200, Compact Air and Compact Air. This model offers protection to the head, the shoulders and the neck. It is equipped with full safety helmet. This system procures air to the user via the supply hose connected between PAPR (equipped with filters) and the hood. The filtered airflow enters by the front of the hood and leaves the hood via the face collar or the neck bib.
Lieferant:
HARTMANN PAUL
Beschreibung:
Diese latexfreien Einmal-Untersuchungs- und Schutzhandschuhe bestehen aus weichem, blau gefärbtem Nitrilkautschuk.
Artikel-Nr:
(113-0092)
Lieferant:
GM EQUIPEMENT
Hersteller-Artikelnummer::
OJM051
Lokale Artikelnummer::
GMEQOJM051
Beschreibung:
Armstulpen aus LDPE.
VE:
1 * 5.000 ST
Artikel-Nr:
(111-1523)
Lieferant:
CENTURION SAFETY PRODUCTS
Hersteller-Artikelnummer::
S22YA
Lokale Artikelnummer::
CENUS22YA
Beschreibung:
Hitzebeständiger duroplastischer Helm aus glasfaserverstärktem Polyesterharz. Ideal zur Anwendung in Heißbetrieben.
VE:
1 * 1 ST
Artikel-Nr:
(PRSI90-025)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-025
Lokale Artikelnummer::
PRSI90-025
Beschreibung:
Glutathione peroxidase 3 (GPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalysing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular marker for the diagnosis of clear cell type ovarian adenocarcinoma.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI90-026)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-026
Lokale Artikelnummer::
PRSI90-026
Beschreibung:
Glutathione peroxidase 3 (GPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalysing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular marker for the diagnosis of clear cell type ovarian adenocarcinoma.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-490)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-490
Lokale Artikelnummer::
PRSI27-490
Beschreibung:
NPAS1 is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development.
VE:
1 * 50 µG
Lieferant:
HONEYWELL SAFETY
Beschreibung:
The Chainex 2000 is a full stainless steel glove with short cuff and attached textile strap. Chainex 2000 is a fully reversible product range, and is equipped with heavy duty adjustable straps and press stud fastening. Offers excellent cut and puncture protection. The high quality of the chain mesh reduces the numbers of repairs, and extends the life time of the glove.
Lieferant:
CEMO
Beschreibung:
Spill Control, Fastening element, KV galvanised steel, 200×200 mm, 1 kg
Lieferant:
HONEYWELL SAFETY
Beschreibung:
This durable glove made from neoprene provides protection against a wide range of chemical products (detergents, some solvents, acids and bases).
Artikel-Nr:
(DAKLCREDO_56L)
Lieferant:
DAKLAPACK
Hersteller-Artikelnummer::
CREDO_56L
Lokale Artikelnummer::
DAKLCREDO_56L
Beschreibung:
The Crēdo Cube™ is a passive and reusable shipper qualified to hold chilled medical materials at a safe temperature for up to five days.
VE:
1 * 1 ST
Lieferant:
SARSTEDT
Beschreibung:
These superior quality filter tips are manufactured in a controlled production environment that complies with the strictest purity standards. The filter insert serves as an aerosol barrier protecting the pipette against contaminations, enabling safe pipetting of DN or RNA, toxic or infectious samples.
Lieferant:
CAPITAL SAFETY
Beschreibung:
Protecta® fall arrest harness accessory options provide the opportunity to add extra tool carrying convenience and comfort to a harness.
Artikel-Nr:
(SIAL687278-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
687278-1G
Lokale Artikelnummer::
SIAL687278-1G
Beschreibung:
(R)-1-Boc-3-hydroxypiperidin, Sigma-Aldrich®
VE:
1 * 1 g
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
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