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3-[(3-Pyridinylmethyl)amino]propanenitrile
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3-[(3-Pyridinylmethyl)amino]propanenitrile
Artikel-Nr:
(BOSSBS-9425R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9425R-A555
Lokale Artikelnummer::
BOSSBS-9425R-A555
Beschreibung:
NET-7, also known as TSPAN15 (tetraspanin 15) or TM4SF15 (transmembrane 4 superfamily member 15), is a 294 amino acid multi-pass membrane protein that belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of the tetraspanin family are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth, motility, differentiation, and cancer. Considered molecular facilitators, tetraspanin proteins may regulate vesicle fusion and fission.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1350R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1350R-A555
Lokale Artikelnummer::
BOSSBS-1350R-A555
Beschreibung:
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9425R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9425R-A350
Lokale Artikelnummer::
BOSSBS-9425R-A350
Beschreibung:
NET-7, also known as TSPAN15 (tetraspanin 15) or TM4SF15 (transmembrane 4 superfamily member 15), is a 294 amino acid multi-pass membrane protein that belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of the tetraspanin family are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth, motility, differentiation, and cancer. Considered molecular facilitators, tetraspanin proteins may regulate vesicle fusion and fission.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13283R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13283R-HRP
Lokale Artikelnummer::
BOSSBS-13283R-HRP
Beschreibung:
GAPVD1 is a 1478 amino acid peripheral membrane protein that acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF). GAPVD1 participates in many processes such as insulin receptor internalization, Glut4 trafficking and endocytosis. In addition, depletion of GAPVD1 leads to delayed EGFR degradation by mediating receptor ubiquination through its RGD domain, suggesting that it may be an important mediator of carcinogenesis resulting from Ras protein mutations. There are six isoforms of GAPVD1 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11716R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11716R-HRP
Lokale Artikelnummer::
BOSSBS-11716R-HRP
Beschreibung:
CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue. CRBN functions are thought to be related to energy metabolism, learning and memory. Localized to the cytoplasm, CRBN acts as a protease in mitochondria and is thought to regulate the assembly of KCNT1, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, such as the hippocampus. The gene encoding CRBN belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis. Defects in the CRBN gene are associated with mild mental retardation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11272R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11272R-CY7
Lokale Artikelnummer::
BOSSBS-11272R-CY7
Beschreibung:
Wolfram syndrome protein (WFS1) is an 890 amino acid protein that contains a cytoplasmic N-terminal domain, followed by nine-transmembrane domains and a luminal C-terminal domain. WFS1 is predominantly localized to the endoplasmic reticulum (ER) (1) and its expression is induced in response to ER stress, partially through transcriptional activation (2,3). Research studies have shown that mutations in the WFS1 gene lead to Wolfram syndrome, an autosomal recessive neurodegenerative disorder defined by young-onset, non-immune, insulin-dependent diabetes mellitus and progressive optic atrophy (4).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8319R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8319R-CY5.5
Lokale Artikelnummer::
BOSSBS-8319R-CY5.5
Beschreibung:
LHPP, also known as HDHD2B, is a 270 amino acid protein that exists as a homodimer and is a member of the HAD-like hydrolase superfamily. Expressed in liver, kidney and moderately in brain, LHPP is encoded by a gene located on 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12343R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12343R-A350
Lokale Artikelnummer::
BOSSBS-12343R-A350
Beschreibung:
TRB-1 is a 372 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase superfamily. Expressed ubiquitously with highest expression in bone marrow, thyroid gland, skeletal muscle and pancreas, TRB-1 interacts with MAPK kinases and is thought to regulate the activation of MAP kinses, possibly controlling MAP kinase cascades. The gene encoding TRB-1 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11667R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11667R-CY3
Lokale Artikelnummer::
BOSSBS-11667R-CY3
Beschreibung:
PET112L is the human homolog of the S. cerevisiae COX assembly protein pet112, a protein that is believed to play an important role in the translation of mitochondrial genes. PET112L, also known as HSPC199 or Glu-ADT subunit B (glutamyl-tRNA(Gln) amidotransferase subunit B), is a 557 amino acid protein belonging to the gatB/gatE family of proteins (GatB subfamily) and is believed to play a role in energy metabolism. Localizing to mitochondria, PET112L is expressed in tissues such as heart and muscle, which exhibit high rates of oxidative phosphorylation. The gene encoding PET112L is overexpressed in recurrent ependymoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12264R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12264R
Lokale Artikelnummer::
BOSSBS-12264R
Beschreibung:
FTSJ1 is a 329 amino acid nucleolar protein belonging to the RlmE family and methyltransferase superfamily. Expressed in adult thalamus, hippocampus, amygdala, corpus callosum and caudate nucleus, as well as fetal kidney, lung, liver, brain and lung, FTSJ1 plays a role in rRNA modification and processing. FTSJ1 exists as multiple spliced isoforms which are encoded by a gene located on human chromosome Xp11.23. Notably, defects in the gene encoding FTSJ1 are the cause of mental retardation X-linked type 44 (MRX44) and nonsyndromic X-linked mental retardation (MRX9).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11667R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11667R-FITC
Lokale Artikelnummer::
BOSSBS-11667R-FITC
Beschreibung:
PET112L is the human homolog of the S. cerevisiae COX assembly protein pet112, a protein that is believed to play an important role in the translation of mitochondrial genes. PET112L, also known as HSPC199 or Glu-ADT subunit B (glutamyl-tRNA(Gln) amidotransferase subunit B), is a 557 amino acid protein belonging to the gatB/gatE family of proteins (GatB subfamily) and is believed to play a role in energy metabolism. Localizing to mitochondria, PET112L is expressed in tissues such as heart and muscle, which exhibit high rates of oxidative phosphorylation. The gene encoding PET112L is overexpressed in recurrent ependymoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8053R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8053R-A555
Lokale Artikelnummer::
BOSSBS-8053R-A555
Beschreibung:
KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q; however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8345R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8345R-A647
Lokale Artikelnummer::
BOSSBS-8345R-A647
Beschreibung:
FOP, is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8053R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8053R-FITC
Lokale Artikelnummer::
BOSSBS-8053R-FITC
Beschreibung:
KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q; however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0234R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0234R-HRP
Lokale Artikelnummer::
BOSSBS-0234R-HRP
Beschreibung:
The placental-derived growth factor (PIGF) is a dimeric glycoprotein showing a high degree of sequence similarity to the vascular endothelial growth factor. Alternative splicing of the PIGF primary transcript gives rise to two forms, named PIGF-1 and PIGF-2, which differ only in the insertion of a highly basic 21-amino acid stretch at the carboxyl end. The presence of the PIGF mRNA in thyroid, placenta, lung, and goiter has indicated the tissues where this factor functions. However, the role of PIGF in vascular development has not yet been clearly established.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9653R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9653R
Lokale Artikelnummer::
BOSSBS-9653R
Beschreibung:
C18orf22, also known as HsT169, is a 343 amino acid protein that localizes to the mitochondrion and is expressed as two alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 18. Chromosome 18 houses over 300 protein-coding genes and contains nearly 76 million nucleotide bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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