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3-Fluor-4-methoxybenzylamin
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3-Fluor-4-methoxybenzylamin
Artikel-Nr:
(BOSSBS-7579R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7579R-A555
Lokale Artikelnummer::
BOSSBS-7579R-A555
Beschreibung:
TXNDC5 is a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. ERp19 and ERp46 are two newly discovered ER luminal proteins, related to protein disulphide isomerase. Western and Northern blot analyses have revealed that both ERp19 and ERp46 and their respective mRNAs are highly expressed in the liver as compared with other tissues. Both proteins are enriched in purified liver ER vesicles and were localized specifically to the ER in McA-RH7777 hepatocytes. See Knoblach et al. for details.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12571R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12571R-A488
Lokale Artikelnummer::
BOSSBS-12571R-A488
Beschreibung:
Barrier-to-autointegration factor (BAF) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BAF compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BAF from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0112M-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0112M-A647
Lokale Artikelnummer::
BOSSBS-0112M-A647
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6820R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6820R-A750
Lokale Artikelnummer::
BOSSBS-6820R-A750
Beschreibung:
MAGEA5 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1794R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1794R-A680
Lokale Artikelnummer::
BOSSBS-1794R-A680
Beschreibung:
This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterised by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a monocistronic mRNA early in development, and from a bicistronic mRNA in later stages that also encodes the LAG1 homolog, ceramide synthase 1 gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4291R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4291R-A647
Lokale Artikelnummer::
BOSSBS-4291R-A647
Beschreibung:
Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2679R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2679R-A555
Lokale Artikelnummer::
BOSSBS-2679R-A555
Beschreibung:
Nectin 2 is a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Can form trans-heterodimers with PVRL3/nectin-3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6291R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6291R-A350
Lokale Artikelnummer::
BOSSBS-6291R-A350
Beschreibung:
Phosphatase enzymes catalyse hydrolysis of phosphoric acid esters of various alcohols, e.g. a hexose phosphate, to yield the alcohol and free inorganic phosphate. This may be a way of recycling phosphate in the cell, and the level of phosphate may be elevated under conditions of phosphate starvation (in algae for example). Acid phosphatases have pH optima below 7, whereas alkaline phosphatases are most active above pH 7. Commercial quantities of acid phosphatase are obtained from plant sources e.g. potato and wheat germ, whereas similar quantities of alkaline phosphatase are obtained from animal intestine and bacteria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3441R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3441R-A488
Lokale Artikelnummer::
BOSSBS-3441R-A488
Beschreibung:
Tuberin, or TSC2 (Tuberous sclerosis complex), is implicated as a tumor suppressor. It may function in vesicular transport, and may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between hamartin (TSC1) and tuberin may facilitate vesicular docking. It specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth. Mutations in tuberin lead to constitutive activation of RAP1A in tumors. At least three isoforms of Tuberin exist.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4913R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4913R-A750
Lokale Artikelnummer::
BOSSBS-4913R-A750
Beschreibung:
By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyses ATP, but can also hydrolyse other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity and function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11372R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11372R-A555
Lokale Artikelnummer::
BOSSBS-11372R-A555
Beschreibung:
The synaptogyrin family of proteins are integral membrane proteins containing four transmembrane regions. Synaptogyrins are tyrosine-phosphorylated proteins with two neuronal isoforms (Synaptogyrin-1 and -3) and one ubiquitous isoform (Synaptogyrin-2). Synaptophysin and synaptogyrin represent the major constituents of synaptic vesicles. Synaptogyrin-1 is associated with presynaptic vesicles in neuronal cells. Synaptogyrin-2, also known as cellugyrin, has a tyrosine phosphorylated C-terminal cytoplasmic tail and is involved in the regulation of membrane traffic in non-neuronal cells. Synaptogyrin-3 is expressed mainly in brain and placenta. Synaptogyrin-4 is a 234 amino acid protein encoded by the SYNGR4 gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6820R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6820R-A350
Lokale Artikelnummer::
BOSSBS-6820R-A350
Beschreibung:
MAGEA5 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7674R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7674R-A750
Lokale Artikelnummer::
BOSSBS-7674R-A750
Beschreibung:
This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti PORIMIN (pro oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterised by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11373R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11373R-A488
Lokale Artikelnummer::
BOSSBS-11373R-A488
Beschreibung:
The synaptogyrin family of proteins are integral membrane proteins containing four transmembrane regions. Synaptogyrins are tyrosine-phosphorylated proteins with two neuronal (Synaptogyrins 1 and 3) and one ubiquitous (Synaptogyrin-2) isoform. Synaptophysin and synaptogyrin represent the major constituents of synaptic vesicles. Synaptogyrin-1 is associated with presynaptic vesicles in neuronal cells. Synaptogyrin-2, also known as Cellugyrin has a tyrosine phosphorylated C-terminal cytoplasmic tail, and is involved in the regulation of membrane traffic in non-neuronal cells. Synaptogyrin-3 is expressed mainly in brain and placenta. The SYNGR4 gene encodes for the 234 amino acid protein Synaptogyrin-4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7555R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7555R-A647
Lokale Artikelnummer::
BOSSBS-7555R-A647
Beschreibung:
EphA3 is a member of the Ephrin (Eph) family. The Ephrins and Eph-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the Ephrin A (EphA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the Ephrin B (EphB) class, which are transmembrane proteins. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11632R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11632R-A555
Lokale Artikelnummer::
BOSSBS-11632R-A555
Beschreibung:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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