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3-Fluor-4-methoxybenzylamin
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3-Fluor-4-methoxybenzylamin
Artikel-Nr:
(BOSSBS-5757R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5757R-A488
Lokale Artikelnummer::
BOSSBS-5757R-A488
Beschreibung:
FAM13B1
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8144R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8144R-A555
Lokale Artikelnummer::
BOSSBS-8144R-A555
Beschreibung:
CCDC96
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5839R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5839R-A555
Lokale Artikelnummer::
BOSSBS-5839R-A555
Beschreibung:
Galectin 8
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8501R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8501R-A350
Lokale Artikelnummer::
BOSSBS-8501R-A350
Beschreibung:
RGAG4
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8094R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8094R-A488
Lokale Artikelnummer::
BOSSBS-8094R-A488
Beschreibung:
CCDC89
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7946R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7946R-A647
Lokale Artikelnummer::
BOSSBS-7946R-A647
Beschreibung:
ABHD15
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1845R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1845R-A555
Lokale Artikelnummer::
BOSSBS-1845R-A555
Beschreibung:
LRIG2
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6392R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6392R-A555
Lokale Artikelnummer::
BOSSBS-6392R-A555
Beschreibung:
PCNP
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8105R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8105R-A555
Lokale Artikelnummer::
BOSSBS-8105R-A555
Beschreibung:
CCDC67
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8136R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8136R-A555
Lokale Artikelnummer::
BOSSBS-8136R-A555
Beschreibung:
CCDC61
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11860R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11860R-A647
Lokale Artikelnummer::
BOSSBS-11860R-A647
Beschreibung:
Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases. Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5. Participates in the negative regulation of cell proliferation signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12171R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12171R-A488
Lokale Artikelnummer::
BOSSBS-12171R-A488
Beschreibung:
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1205R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1205R-A680
Lokale Artikelnummer::
BOSSBS-1205R-A680
Beschreibung:
Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fibre and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP3, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p9RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. Plays an important role in generating the circadian rhythm of the aortic myofilament Ca(2+) sensitivity and vascular contractility by modulating the myosin light chain phosphorylation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1712R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1712R-A647
Lokale Artikelnummer::
BOSSBS-1712R-A647
Beschreibung:
Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The cytokeratins are encoded by a family encompassing 30 genes. Among them, 20 are epithelial genes and the remaining 10 are specific for trichocytes.
In the cytoplasm, the keratin filaments conform a complex network which extends from the surface of the nucleus to the cell membrane. Numerous accessory proteins are involved in the genesis and maintenance of such structure. This association between the plasma membrane and the nuclear surface provides important implications for the organization of the cytoplasm and cellular communication mechanisms. Apart from the relatively static functions provided in terms of supporting the nucleus and providing tensile strength to the cell, the cytokeratin networks undergo rapid phosphate exchanges mediated depolymerization, with important implications in the more dynamic cellular processes such as mitosis and post-mitotic period, cell movement and differentiation. Cytokeratins interact with desmosomes and hemidesmosomes, thus collaborating to cell-cell adhesion and basal cell-underlying connective tissue connection.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3370R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3370R-A647
Lokale Artikelnummer::
BOSSBS-3370R-A647
Beschreibung:
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. [provided by RefSeq, Jul 2013].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12248R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12248R-A647
Lokale Artikelnummer::
BOSSBS-12248R-A647
Beschreibung:
Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).
VE:
1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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