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1-(4-Chlorophenyl)-1-methylethylamine


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Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-3581R-CY3
Lokale Artikelnummer:: BOSSBS-3581R-CY3
Beschreibung:   Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1. Also corepressor for ERBB4. Inhibits E2F1 activity by stimulating E2F1-HDAC1 complex formation and inhibiting E2F1 acetylation. May serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of RB1. Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger. Also specifically sumoylates IRF7, thereby inhibiting its transactivation activity. Ubiquitinates p53/TP53 leading to its proteosomal degradation; the function is enhanced by MAGEC2 and MAGEA2, and possibly MAGEA3 and MAGEA6. Mediates the nuclear localization of KOX1, ZNF268 and ZNF300 transcription factors.
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-3423R-CY7
Lokale Artikelnummer:: BOSSBS-3423R-CY7
Beschreibung:   Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1. Also corepressor for ERBB4. Inhibits E2F1 activity by stimulating E2F1-HDAC1 complex formation and inhibiting E2F1 acetylation. May serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of RB1. Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger. Also specifically sumoylates IRF7, thereby inhibiting its transactivation activity. Ubiquitinates p53/TP53 leading to its proteosomal degradation; the function is enhanced by MAGEC2 and MAGEA2, and possibly MAGEA3 and MAGEA6. Mediates the nuclear localization of KOX1, ZNF268 and ZNF300 transcription factors.
VE:  1 * 100 µl
Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-3423R-A680
Lokale Artikelnummer:: BOSSBS-3423R-A680
Beschreibung:   Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1. Also corepressor for ERBB4. Inhibits E2F1 activity by stimulating E2F1-HDAC1 complex formation and inhibiting E2F1 acetylation. May serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of RB1. Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger. Also specifically sumoylates IRF7, thereby inhibiting its transactivation activity. Ubiquitinates p53/TP53 leading to its proteosomal degradation; the function is enhanced by MAGEC2 and MAGEA2, and possibly MAGEA3 and MAGEA6. Mediates the nuclear localization of KOX1, ZNF268 and ZNF300 transcription factors.
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-3423R-A647
Lokale Artikelnummer:: BOSSBS-3423R-A647
Beschreibung:   Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1. Also corepressor for ERBB4. Inhibits E2F1 activity by stimulating E2F1-HDAC1 complex formation and inhibiting E2F1 acetylation. May serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of RB1. Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger. Also specifically sumoylates IRF7, thereby inhibiting its transactivation activity. Ubiquitinates p53/TP53 leading to its proteosomal degradation; the function is enhanced by MAGEC2 and MAGEA2, and possibly MAGEA3 and MAGEA6. Mediates the nuclear localization of KOX1, ZNF268 and ZNF300 transcription factors.
VE:  1 * 100 µl
Lieferant:  GRANT INSTRUMENTS
Beschreibung:   Plattform für 8 Röhrchen bis 30 mm Ø, und 22 Röhrchen bis 15 mm Ø für PTR-60
Lieferant:  Sigma-Aldrich
Beschreibung:   Vitamin K1 (Phytomenadion, Phyllochinon), Sigma-Aldrich®
Lieferant:  COMBI-BLOCKS
Beschreibung:   2-Chlor-3-methyl-5-nitropyridin
Lieferant:  MACHEREY-NAGEL
Beschreibung:   This derivitisation reagent is recommended for alcohols, primary and secondary amines as well as for thiols under mild, neutral conditions. MBTFA also forms very volatile derivatives with carbohydrates.
Artikel-Nr: (MOLEM43851178)

Lieferant:  Molekula
Hersteller-Artikelnummer:: M43851178
Lokale Artikelnummer:: MOLEM43851178
Beschreibung:   Bisacrylamid
VE:  1 * 100 g
Market Source Item This is a MarketSource item. Additional charges may apply
Lieferant:  JULABO GmbH
Beschreibung:   Kalibrier-Thermostate sind für Anwendungen in Kalibrierlaboren, wie z. B. ISO, DKD, NAMAS, UKAS, und für Anforderungen gemäß DIN EN ISO 9001:2000 vorgesehen. Die Einheiten verfügen über eine Kammer mit konstanter Temperatur und eignen sich zur präzisen Kalibrierung von Temperatursensoren, Messgeräten und Thermometern gemäß nationaler und internationaler Standards. Die Modelle mit Kältemaschine eignen sich für alle Temperaturen von –30 bis +200 °C sowie als Kalibrier-Thermostate für Temperaturen von 50 bis 300 °C. Der optionale Präzisions-Referenzsensor ermöglicht das Messen von Referenztemperaturen. Die Bäder sind mit einer PID-Kaskaden-Temperaturregelung für höchste interne und externe Temperaturkonstanz und einem integrierten Programmgeber für 10 Programmschritte ausgestattet.
Lieferant:  Merck Millipore (Calbiochem‎)
Hersteller-Artikelnummer:: 250233-5
Lokale Artikelnummer:: CALB250233-5
Beschreibung:   Cytochalasin B (aus Helminthosporium dematioideum), Millipore®
VE:  1 * 5 mg
Lieferant:  Serva
Beschreibung:   Säurefuchsin
Lieferant:  FLUOROCHEM
Beschreibung:   4-Chlor-6-methyl-2-(trifluormethyl)chinolin
Lieferant:  Sigma-Aldrich
Beschreibung:   Cytochalasin B (aus Dreschslera dematioidea), Sigma-Aldrich®
Lieferant:  CHEMPUR SILANE
Beschreibung:   Chlor(methyl)phenylsilan
Lieferant:  Thermo Scientific
Beschreibung:   5-Chlor-3-methyl-1-phenyl-1H-pyrazol
Preis auf Anfrage
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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