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BIOSS INC
Artikel-Nr:
(BOSSBS-8026R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8026R-A555
Lokale Artikelnummer::
BOSSBS-8026R-A555
Beschreibung:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. The protein encoded by this gene is highly expressed in leukocytes, but its exact function is unknown. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5453R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5453R-CY7
Lokale Artikelnummer::
BOSSBS-5453R-CY7
Beschreibung:
The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit (95 kDa) possesses a single transmembrane domain, whereas the alpha subunit (135 kDa) is completely extracellular. The insulin receptor exhibits receptor tyrosine kinase (RTK) activity. RTKs are single pass transmembrane receptors that possess intrinsic cytoplasmic enzymatic activity, catalyzing the transfer of the gamma phosphate of ATP to tyrosine residues in protein substrates. RTKs are essential components of signal transduction pathways that affect cell proliferation, differentiation, migration and metabolism.Included in this large protein family are the insulin receptor and the receptors for growth factors such as epidermal growth factor, fibroblast growth factor and vascular endothelial growth factor. Receptor activation occurs through ligand binding, which facilitates receptor dimerization and autophosphorylation of specific tyrosine residues in the cytoplasmic portion. The interaction of insulin with the alpha subunit of the insulin receptor activates the protein tyrosine kinase of the beta subunit, which then undergoes an autophosphorylation that increases its tyrosine kinase activity. Three adapter proteins, IRS1, IRS2 and Shc, become phosphorylated on tyrosine residues following insulin receptor activation. These three phosphorylated proteins then interact with SH2 domain containing signaling proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2539R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2539R-A350
Lokale Artikelnummer::
BOSSBS-2539R-A350
Beschreibung:
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10130R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10130R-FITC
Lokale Artikelnummer::
BOSSBS-10130R-FITC
Beschreibung:
APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3191R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3191R-HRP
Lokale Artikelnummer::
BOSSBS-3191R-HRP
Beschreibung:
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0015R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0015R-A680
Lokale Artikelnummer::
BOSSBS-0015R-A680
Beschreibung:
The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6981R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6981R-A680
Lokale Artikelnummer::
BOSSBS-6981R-A680
Beschreibung:
Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6351R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6351R-A680
Lokale Artikelnummer::
BOSSBS-6351R-A680
Beschreibung:
his gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7769R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7769R-A750
Lokale Artikelnummer::
BOSSBS-7769R-A750
Beschreibung:
SEPT1 is a member of the septin family of GTPases. Members of this family are required for cytokinesis. SEPT1 is associated with the tau-based paired helical filament core, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7724R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7724R-A680
Lokale Artikelnummer::
BOSSBS-7724R-A680
Beschreibung:
This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3597R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3597R-A750
Lokale Artikelnummer::
BOSSBS-3597R-A750
Beschreibung:
Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a homolog of VASA proteins in Drosophila and several other species. The gene is specifically expressed in the germ cell lineage in both sexes and functions in germ cell development. Multiple transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0938R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0938R-CY5
Lokale Artikelnummer::
BOSSBS-0938R-CY5
Beschreibung:
Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2950R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2950R-CY5.5
Lokale Artikelnummer::
BOSSBS-2950R-CY5.5
Beschreibung:
Converts cytosine to uracil or 5-methylcytosine to thymine by deaminating carbon number 4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4642R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4642R-A750
Lokale Artikelnummer::
BOSSBS-4642R-A750
Beschreibung:
Kilham Rat Virus/KRV-VP1/KRV-VP2 (C-terminus).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0677R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0677R-A750
Lokale Artikelnummer::
BOSSBS-0677R-A750
Beschreibung:
Binds to TEK/TIE2, competing for the ANGPT1 binding site and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1446R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1446R-A555
Lokale Artikelnummer::
BOSSBS-1446R-A555
Beschreibung:
Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilisation of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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