3-(Trifluoromethyl)isatoic+anhydride
Artikel-Nr:
(BOSSBS-6947R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6947R-A555
Lokale Artikelnummer::
BOSSBS-6947R-A555
Beschreibung:
KRT82 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12528R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12528R-CY3
Lokale Artikelnummer::
BOSSBS-12528R-CY3
Beschreibung:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7335R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7335R-HRP
Lokale Artikelnummer::
BOSSBS-7335R-HRP
Beschreibung:
MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12343R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12343R-A555
Lokale Artikelnummer::
BOSSBS-12343R-A555
Beschreibung:
TRB-1 is a 372 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase superfamily. Expressed ubiquitously with highest expression in bone marrow, thyroid gland, skeletal muscle and pancreas, TRB-1 interacts with MAPK kinases and is thought to regulate the activation of MAP kinses, possibly controlling MAP kinase cascades. The gene encoding TRB-1 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12343R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12343R-HRP
Lokale Artikelnummer::
BOSSBS-12343R-HRP
Beschreibung:
TRB-1 is a 372 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase superfamily. Expressed ubiquitously with highest expression in bone marrow, thyroid gland, skeletal muscle and pancreas, TRB-1 interacts with MAPK kinases and is thought to regulate the activation of MAP kinses, possibly controlling MAP kinase cascades. The gene encoding TRB-1 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7335R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7335R-FITC
Lokale Artikelnummer::
BOSSBS-7335R-FITC
Beschreibung:
MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7576R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7576R
Lokale Artikelnummer::
BOSSBS-7576R
Beschreibung:
Cellular senescence, the terminal nondividing state that normal cells enter following completion of their proliferative potential, is the dominant phenotype in hybrids of normal and immortal cells. Fusions of immortal human cell lines with each other have led to their assignment to one of several complementation groups. SEN1 or MORF4 is a gene on chromosome 4 that induces a senescent-like phenotype in cell lines assigned to complementation group B. It is capable of reversing the immortal phenotype of a subset of immortal cells. Overexpression of SEN1 in HeLa cells ultimately caused abnormal nuclear morphology and cell death.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7335R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7335R-A488
Lokale Artikelnummer::
BOSSBS-7335R-A488
Beschreibung:
MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13475R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13475R-A350
Lokale Artikelnummer::
BOSSBS-13475R-A350
Beschreibung:
Glucosamine 6-phosphate N-acetyltransferase (GNA1), also designated phosphoglucosamine transacetylase or phosphoglucosamine acetylase, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. GNA1, a peripheral membrane protein containing one N-acetyltransferase domain, is expressed in the colon and maps to cytoband 14q22.1. The protein localizes to the Golgi apparatus and the endosome. It is important for UDP-GlcNAc biosynthesis pathway. GNA1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13475R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13475R-FITC
Lokale Artikelnummer::
BOSSBS-13475R-FITC
Beschreibung:
Glucosamine 6-phosphate N-acetyltransferase (GNA1), also designated phosphoglucosamine transacetylase or phosphoglucosamine acetylase, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. GNA1, a peripheral membrane protein containing one N-acetyltransferase domain, is expressed in the colon and maps to cytoband 14q22.1. The protein localizes to the Golgi apparatus and the endosome. It is important for UDP-GlcNAc biosynthesis pathway. GNA1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2675R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2675R-CY5.5
Lokale Artikelnummer::
BOSSBS-2675R-CY5.5
Beschreibung:
a-Fodrin is a universally expressed membrane associated cytoskeletal protein consisting of alpha and beta subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. Alpha Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N terminal 150 kDa, C terminal 120 kDa, and 35 kDa major products. Cleavage of alpha Fodrin leads to membrane malfunction and cell shrinkage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13034R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13034R-CY5
Lokale Artikelnummer::
BOSSBS-13034R-CY5
Beschreibung:
DTYMK is a 212 amino acid protein that belongs to the thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. DTYMK expression levels peak during the S phase (synthesis phase) of the cell cycle, further supporting the role of DTYMK in DNA synthesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13325R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13325R
Lokale Artikelnummer::
BOSSBS-13325R
Beschreibung:
GDE4 is a 314 amino acid cytoplasmic and multi-pass membrane protein that belongs to the glycerophosphoryl diester phosphodiesterase family. Expressed in small intestine, placenta, kidney, ovary, thymus, pancreas, spleen, liver and peripheral blood leukocytes, GDE4 contains one GDPD domain and exists as three alternatively spliced isoforms. GDE4 is encoded by a gene that maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11373R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11373R-CY7
Lokale Artikelnummer::
BOSSBS-11373R-CY7
Beschreibung:
The synaptogyrin family of proteins are integral membrane proteins containing four transmembrane regions. Synaptogyrins are tyrosine-phosphorylated proteins with two neuronal (Synaptogyrins 1 and 3) and one ubiquitous (Synaptogyrin-2) isoform. Synaptophysin and synaptogyrin represent the major constituents of synaptic vesicles. Synaptogyrin-1 is associated with presynaptic vesicles in neuronal cells. Synaptogyrin-2, also known as Cellugyrin has a tyrosine phosphorylated C-terminal cytoplasmic tail, and is involved in the regulation of membrane traffic in non-neuronal cells. Synaptogyrin-3 is expressed mainly in brain and placenta. The SYNGR4 gene encodes for the 234 amino acid protein Synaptogyrin-4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12906R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12906R-CY7
Lokale Artikelnummer::
BOSSBS-12906R-CY7
Beschreibung:
KLHL28 is a 571 amino acid protein similar to the Drosophila kelch protein. KLHL26 contains six kelch repeats and one BTB (POZ) domain. The BTB (broad complex, tramtrack and bric-a-brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KLHL28 is expressed as two isoforms produced by alternative splicing.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
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