4,4-Dimethylcyclohexa-1,5-dienylboronsäure+Mononatriumsalz
Artikel-Nr:
(MOLE13559814-1KG)
Lieferant:
Molekula
Hersteller-Artikelnummer::
13559814-1KG
Lokale Artikelnummer::
MOLE13559814-1KG
Beschreibung:
DL-Apfelsäure
VE:
1 * 1 kg
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Artikel-Nr:
(PRSI92-365)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-365
Lokale Artikelnummer::
PRSI92-365
Beschreibung:
The IL-17 family include IL-17A, IL-17B, IL-17C, IL-17D, IL-17E (also called IL-25), and IL-17F. The family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. All members of the IL-17 family have a similar protein structure, with four highly conserved cysteine residues critical to their 3-dimensional shape, yet they have no sequence similarity to any other known cytokines. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes.
VE:
1 * 50 µG
Artikel-Nr:
(ASTA31020-5G)
Lieferant:
ASTATECH
Hersteller-Artikelnummer::
31020-5G
Lokale Artikelnummer::
ASTA31020-5G
Beschreibung:
3-Chlorisonicotinonitril
VE:
1 * 5 g
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Artikel-Nr:
(PRSI33-262)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-262
Lokale Artikelnummer::
PRSI33-262
Beschreibung:
This antibody recognises an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of TAG-72 antibody with a GCDFP-15 antibody is valuable in the diagnosis of apocrine carcinoma.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-367)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-367
Lokale Artikelnummer::
PRSI29-367
Beschreibung:
PCBP1 appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. PCBP1 is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.This intronless gene is thought to be generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding proteins. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(STMC100-1398)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
100-1398
Lokale Artikelnummer::
STMC100-1398
Beschreibung:
Stimulating T cells with BKV (LT) Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. BKV Peptide pool is a lyophilised mixture of 171 peptides from the Large T (LT) antigen of BK polyomavirus (BKV), and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 695 on LT antigen. LT antigen is an early viral protein (Low <i>et al.</i>) that contributes to the transformation and maintenance of host cells (Nakshatri <i>et al.</i>). It has been found to bind to a subset of tumor suppressor proteins (Harris <i>et al.</i>), and its co-expression with p53 has been observed in polyomavirus-associated nephropathy (Seemayer <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
VE:
1 * 1 LE
New Product
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Lieferant:
EUTECH
Beschreibung:
The CyberScan pH 600 series enables a wireless and cable-free data transfer with infrared IrDA technology. Data can be simply sent from the meter to a PC with the press of a button.
Artikel-Nr:
(STMC100-1397)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
100-1397
Lokale Artikelnummer::
STMC100-1397
Beschreibung:
Stimulating T cells with HPV18 (L2) peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. A lyophilised mixture of 113 peptides from minor capsid protein L2 of human papillomavirus type 18 (HPV18), HPV18 (L2) peptide pool consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 462 on L2. With two nuclear localization signals, L2 may enter the nuclei of host cells via several import pathways mediated by Kap α2β1 heterodimers, Kap β2, and Kap β (Klucevsek <i>et al.</i>). L2 can also assemble into virus-like particles, and may have a role in encapsidation (Stauffer <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
VE:
1 * 1 LE
New Product
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Artikel-Nr:
(STMC100-1409)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
100-1409
Lokale Artikelnummer::
STMC100-1409
Beschreibung:
Stimulating T cells with VZV (IE63) peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. VZV (IE63) peptide pool is a lyophilised mixture of 67 peptides from the transcriptional regulator ICP22 homolog (IE63) of Varicella-zoster virus (VZV; strain Oka vaccine), and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 278 on IE63. Expressed during VZV latency and reactivation (Lungu <i>et al.</i>), IE63 demonstrates repressive activity in both the cytoplasm and nucleus of infected cells (Bontems <i>et al.</i>). Host interferon alpha (IFN-α) activity is inhibited by VZV IE63, which likely contributes to VZV pathogenesis (Ambagala and Cohen). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
VE:
1 * 1 LE
New Product
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Lieferant:
MP Biomedicals
Beschreibung:
Succinic acid is a dicarboxylic acid that occurs in nature in such organisms as fungi and lichens. In eukaryotes, succiniate, the anion of succinic acid, is an intermediate in the citric acid cycle, being formed from succinyl CoA and being converted to fumarate. Bacteria and plants can produce succinate from acetate or acetyl CoA, in the glyoxylate cycle.
Artikel-Nr:
(118-0387)
Lieferant:
GASTEC
Hersteller-Artikelnummer::
HBE
Lokale Artikelnummer::
GASTHBE
Beschreibung:
Accessory for gas detection, Gastec Handbuch: 15. Auflage, GASTEC Umweltanalytik-Technologie
VE:
1 * 1 ST
Artikel-Nr:
(PRSI33-261)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-261
Lokale Artikelnummer::
PRSI33-261
Beschreibung:
This antibody recognises an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of TAG-72 Ab with a GCDFP-15 Ab is valuable in the diagnosis of apocrine carcinoma.
VE:
1 * 100 µG
Lieferant:
Mettler - Toledo
Beschreibung:
Mobiles Zweikanal-Messgerät zur gleichzeitigen Bestimmung von pH, mV oder Ionenkonzentration und gelöstem Sauerstoff.
Lieferant:
Sigma-Aldrich
Beschreibung:
DL-Apfelsäure, Sigma-Aldrich®
Artikel-Nr:
(STMC100-1392)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
100-1392
Lokale Artikelnummer::
STMC100-1392
Beschreibung:
Stimulating T cells with HPV16 (L1) Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. HPV16 (L1) Peptide pool is a lyophilised mixture of 124 peptides from major capsid protein L1 of human papillomavirus type 16 (HPV16) consisting of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 505 on L1. L1 enters the nuclei of host cells via a Kap α2β1-mediated pathway (Nelson <i>et al.</i>). It cooperates with E2, another viral protein, to enhance viral DNA replication (Siddiqa <i>et al.</i>). L1 pentamers can assemble into virus-like particles (Chen <i>et al.</i> 2000; Chen <i>et al.</i> 2001). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
VE:
1 * 1 LE
New Product
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Artikel-Nr:
(SARS10.252.020)
Lieferant:
SARSTEDT
Hersteller-Artikelnummer::
10.252.020
Lokale Artikelnummer::
SARS10.252.020
Beschreibung:
Urinsammelsystem, das speziell für den Transport und die Lagerung von Urin entwickelt wurde.
VE:
1 * 500 ST
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