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2-(Trifluoromethyl)quinoline
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2-(Trifluoromethyl)quinoline
Lieferant:
Biotium
Beschreibung:
Granulocyte/macrophage - Colony-stimulating factor (GM-CSF) is a hematopoietic factor that is produced by activated T-cells, B-cells, mast cells, macrophages, fibroblasts, and endothelial cells. In addition to supporting colony formation of granulocyte/macrophage progenitors, GM-CSF is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors.
Artikel-Nr:
(BOSSBS-0385R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0385R-A750
Lokale Artikelnummer::
BOSSBS-0385R-A750
Beschreibung:
Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fibre dynamics and cell migration.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3864R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3864R-A488
Lokale Artikelnummer::
BOSSBS-3864R-A488
Beschreibung:
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1824R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1824R-A647
Lokale Artikelnummer::
BOSSBS-1824R-A647
Beschreibung:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3864R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3864R-A647
Lokale Artikelnummer::
BOSSBS-3864R-A647
Beschreibung:
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1824R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1824R-HRP
Lokale Artikelnummer::
BOSSBS-1824R-HRP
Beschreibung:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3864R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3864R-A350
Lokale Artikelnummer::
BOSSBS-3864R-A350
Beschreibung:
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12873R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12873R-HRP
Lokale Artikelnummer::
BOSSBS-12873R-HRP
Beschreibung:
Bone morphogenic proteins (BMPs) are members of the TGF Beta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGF Beta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12873R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12873R-A647
Lokale Artikelnummer::
BOSSBS-12873R-A647
Beschreibung:
Bone morphogenic proteins (BMPs) are members of the TGF Beta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGF Beta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6473R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6473R-CY5.5
Lokale Artikelnummer::
BOSSBS-6473R-CY5.5
Beschreibung:
Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle (PubMed:25537362). Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane. May regulate AChR phosphorylation and clustering through activation of ABL1 and Src family kinases which in turn regulate MUSK. DVL1 and PAK1 that form a ternary complex with MUSK are also important for MUSK-dependent regulation of AChR clustering. May positively regulate Rho family GTPases through FNTA. Mediates the phosphorylation of FNTA which promotes prenylation, recruitment to membranes and activation of RAC1 a regulator of the actin cytoskeleton and of gene expression. Other effectors of the MUSK signaling include DNAJA3 which functions downstream of MUSK. May also play a role within the central nervous system by mediating cholinergic responses, synaptic plasticity and memory formation (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5690R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5690R-CY3
Lokale Artikelnummer::
BOSSBS-5690R-CY3
Beschreibung:
A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0376R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0376R
Lokale Artikelnummer::
BOSSBS-0376R
Beschreibung:
The protein encoded by this gene is an enzyme that synthesises the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyses the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1770R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1770R-CY3
Lokale Artikelnummer::
BOSSBS-1770R-CY3
Beschreibung:
ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and for completion of the abscission stage of cytokinesis. May also play a role in axon growth and the formation of axonal branches.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6473R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6473R-HRP
Lokale Artikelnummer::
BOSSBS-6473R-HRP
Beschreibung:
Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle (PubMed:25537362). Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane. May regulate AChR phosphorylation and clustering through activation of ABL1 and Src family kinases which in turn regulate MUSK. DVL1 and PAK1 that form a ternary complex with MUSK are also important for MUSK-dependent regulation of AChR clustering. May positively regulate Rho family GTPases through FNTA. Mediates the phosphorylation of FNTA which promotes prenylation, recruitment to membranes and activation of RAC1 a regulator of the actin cytoskeleton and of gene expression. Other effectors of the MUSK signaling include DNAJA3 which functions downstream of MUSK. May also play a role within the central nervous system by mediating cholinergic responses, synaptic plasticity and memory formation (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6690R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6690R-CY5.5
Lokale Artikelnummer::
BOSSBS-6690R-CY5.5
Beschreibung:
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11093R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11093R-HRP
Lokale Artikelnummer::
BOSSBS-11093R-HRP
Beschreibung:
This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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