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N-Methyl-N-[2-(4-methylphenoxy)benzyl]amine
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N-Methyl-N-[2-(4-methylphenoxy)benzyl]amine
Artikel-Nr:
(PRSI96-121)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-121
Lokale Artikelnummer::
PRSI96-121
Beschreibung:
CD36 (Cluster of Differentiation 36) is also known as platelet membrane glycoprotein IV (GPIV), fatty acid translocase (FAT), thrombospondin receptor, collagen receptor, and scavenger receptor class B, member 3 (SRB3), is a member of the class B scavenger receptor family of cell surface proteins. The human CD36 gene encodes a single chain 472 amino acid residue protein containing both an N- and a C-terminal cytoplasmic tail and an extracellular loop.CD36 is found on platelets, erythrocytes, monocytes, differentiated adipocytes, mammary epithelial cells, spleen cells and some skin microdermal endothelial cells. CD36 is a multiligand pattern recognition receptor that interacts with a large number of structurally dissimilar ligands, including long chain fatty acid (LCFA), advanced glycation end products (AGE), thrombospondin-1, oxidized low-density lipoproteins (oxLDLs), high density lipoprotein (HDL), phosphatidylserine, apoptotic cells, beta-amyloid fibrils (fAβ), collagens I and IV, and Plasmodium falciparum infected erythrocytes. CD36 is required for the anti-angiogenic effects of thrombospondin1 In the corneal neovascularisation assay. On binding a ligand the protein and ligand are internalized. This internalisation is independent of macropinocytosis and occurs by an actin dependent mechanism requiring the activation Src-family kinases, JNK and Rho-family GTPases. CD36 ligands have also been shown to promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-239)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-239
Lokale Artikelnummer::
PRSI91-239
Beschreibung:
Protein SCO1 Homolog, Mitochondrial (SCO1) is a member of the SCO1/2 family. SCO1 has a homodimer structure. SCO1 is located in mitochondrion and is highly expressed in muscle, heart, and brain. It is characterized by high rates of Oxidative Phosphorylation (OxPhos). SCO1 is thought to play a important role in cellular copper homeostasis, mitochondrial redox signaling and insertion of copper into the active site of COX. The defects of SCO1 can result in Mitochondrial Complex IV Deficiency (MT-C4D). A disorder of the mitochondrial respiratory chain has heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-568)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-568
Lokale Artikelnummer::
PRSI29-568
Beschreibung:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IV is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and of proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IV is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and of proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.
VE:
1 * 100 µG
Lieferant:
B. Braun
Beschreibung:
Introcan Safety Sicherheitsvenenverweilkanülen mit selbstaktivierendem Schutzmechanismus zur Vermeidung von Nadelstichverletzungen und den damit verbundenen Infektionsrisiken.
Artikel-Nr:
(PRSI25-366)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-366
Lokale Artikelnummer::
PRSI25-366
Beschreibung:
Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 gene has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells.Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
N,N-Dimethylformamiddi-tert-butylacetal ≥90,0% zur GC-Derivatisierung, Sigma-Aldrich®
Artikel-Nr:
(PRSI6271)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6271
Lokale Artikelnummer::
PRSI6271
Beschreibung:
ApoA5 Antibody: Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but several evidences from vitro studies indicate that this apolipoprotein involves in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI33-420)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-420
Lokale Artikelnummer::
PRSI33-420
Beschreibung:
Recognises a protein of 180 kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This mAb potently blocks LFA-1 dependent homotypic cell aggregation.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(BSBTPB9247)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
PB9247
Lokale Artikelnummer::
BSBTPB9247
Beschreibung:
Polyclonal antibody for 575 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: Flow Cytometry. Reactive species: Human. 575 information: Molecular Weight: 42200 MW; Subcellular Localization: Cell membrane ; Single-pass type I membrane protein . Melanosome . Colocalizes with SLC16A1 and SLC16A8. Identified by mass spectrometry in melanosome fractions from stage I to stage IV; Tissue Specificity: Present only in vascular endothelium in non- neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas.
VE:
1 * 100 µG
Artikel-Nr:
(SIAL32869-50G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
32869-50G
Lokale Artikelnummer::
SIAL32869-50G
Beschreibung:
trans-1,2-Diaminocyclohexan-N,N,N',N'-tetraessigsäure Monohydrat, Sigma-Aldrich®
VE:
1 * 50 g
Artikel-Nr:
(PRSI7471)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7471
Lokale Artikelnummer::
PRSI7471
Beschreibung:
The matrix metalloproteinase (MMP) family are a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP9 degrades type IV and V collagens (2) and studies suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow (3) and plays a role in tumor-associated tissue remodeling.
VE:
1 * 100 µG
Lieferant:
KIMBERLY CLARK
Beschreibung:
Kimtech™ Opal™ Nitrilhandschuhe schützen vor Kontamination durch Chemikalienspritzer und Mikroorganismen. Puderfrei, beidhändig, mit Rollrand und strukturierten Fingerspitzen. Da diese Handschuhe frei von Naturkautschuklatex und Vulkanisationsmittel sind, wird das Risiko von Hautreaktionen im Zusammenhang mit Handschuhen des Typs I und IV verringert.
Lieferant:
Sigma-Aldrich
Beschreibung:
trans-1,2-Diaminocyclohexan-N,N,N',N'-tetraessigsäure Monohydrat, Sigma-Aldrich®
Artikel-Nr:
(EHERC12194000)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C12194000
Lokale Artikelnummer::
EHERC12194000
Beschreibung:
trans-1,2-Diaminocyclohexan-N,N,N',N'-tetraessigsäure Monohydrat
VE:
1 * 0,25 g
Artikel-Nr:
(PRSI92-162)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-162
Lokale Artikelnummer::
PRSI92-162
Beschreibung:
Tubulin Beta-4A Chain (TUBB4A) is a cytoplasmic peptide containing 444 amino acids. TUBB4A is a member of the Tubulin family. Tubulin is the major constituent of microtubules. Tubulin is a dimer composed of one alpha and one beta tubulin molecule; there are many forms of beta tubulins, Beta II and Beta IV Tubulin are ubiquitously expressed. Beta-III Tubulin, also known as Tubulin Beta-4, is regarded as a neuron-specific marker. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-785)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-785
Lokale Artikelnummer::
PRSI27-785
Beschreibung:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
VE:
1 * 100 µG
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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