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Artikel-Nr:
(BOSSBS-9509R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9509R-HRP
Lokale Artikelnummer::
BOSSBS-9509R-HRP
Beschreibung:
Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutation in the genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 3B (LRRC3B), also designated LRP15, is a 259 amino acid protein that contains 3 LRR repeats. The gene encoding LRRC3B is a tumor suppressor gene that is regulated by DNA methylation. Decreased expression of LRRC3B has been shown in colorectal cancer and gastric cancer, making LRRC3B a candidate marker for those cancers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12350R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12350R-CY5
Lokale Artikelnummer::
BOSSBS-12350R-CY5
Beschreibung:
The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and in the control of gene expression. MIXL1 (Mix1 homeobox-like 1), also known as MIXL, is a 232 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Expressed in lymph tissues, MIXL1 functions as a transcription factor that plays an essential role in axial mesendoderm morphogenesis and endoderm formation and is also required for cellular differentiation during blood development. Additionally, MIXL1 is involved in maturation of heart and gut tissue during embryogenesis and may also act as a negative regulator of brachyury expression. Overexpression of MIXL1 is associated with non-Hodgkin and Hodgkin lymphomas, suggesting a role in carcinogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD222948-250MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD222948-250MG
Lokale Artikelnummer::
BLDPBD222948-250MG
Beschreibung:
N2,N2,N2',N2',N7,N7,N7',N7'-Octakis(4-methoxyphenyl)-9,9'-spirobi[fluorene]-2,2',7,7'-tetraamine 98%
VE:
1 * 250 mg
Lieferant:
Thermo Scientific
Beschreibung:
5-(N-2-3-Dihydroxypropylacetimido)-2,4,6-triiodo-N,N'-bis(2,3-dihydroxypropyl)isophthalamide
Lieferant:
BIOMOL RESEARCH LABORATORIES
Beschreibung:
Carbenicillin Dinatriumsalz
Artikel-Nr:
(BLDPBD18140-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD18140-1G
Lokale Artikelnummer::
BLDPBD18140-1G
Beschreibung:
N-Fmoc-N'-trityl-D-histidine 99% contains 3% CH2Cl2
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-11879R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11879R-CY5
Lokale Artikelnummer::
BOSSBS-11879R-CY5
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. Leucine-rich glioma-inactivated protein 3 (LGI3), also known as LGI1-like protein 4 (LGIL4) or leucine-rich repeat LGI family member 3, is a 548 amino acid secretory protein. LGI3 contains five LRR repeats and seven EAR repeats. Widely expressed, with highest levels in brain and lung, LGI3 has been shown to colocalize with endocytosis-associated proteins, lipid raft markers, and Syntaxin. The gene encoding LGI3 maps to chromosome 8p21.3.
VE:
1 * 100 µl
Artikel-Nr:
(M108-1KG)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRCM108-1KG
Beschreibung:
TRIS HCl (Tris(hydroxymethyl)aminomethan Hydrochlorid) ≥99,5%, Proteomik-Qualität
VE:
1 * 1 kg
Lieferant:
Thermo Scientific
Beschreibung:
N-ɑ-Fmoc-N-Trityl-L-histidine 98%
Artikel-Nr:
(BOSSBS-6233R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6233R
Lokale Artikelnummer::
BOSSBS-6233R
Beschreibung:
NMT2 catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. several distinct NMTs exist, varying in apparent molecular weight and /or subcellular distribution.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
1,3-benzothiazol-5-amine 95%
Lieferant:
PanReac AppliChem
Beschreibung:
Amphotericin B
Artikel-Nr:
(BOSSBS-9856R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9856R-A680
Lokale Artikelnummer::
BOSSBS-9856R-A680
Beschreibung:
Hyperpolarisation-activated, cyclic nucleotide-binding channels (HCN) are voltage-gated cation channels that are activated by direct binding of intracellular cyclic nucleotides. The HCN family consists of four members (HCN1-4), each with a core transmembrane segment domain and a C-terminal 120 amino-acid cyclic nucleotide-binding domain motif. HCN channels are expressed in the brain, heart, thalamus and testis. The pacemaker properties of HCN channels contribute to spontaneous rhythmic activity in the brain and heart. HCN3 contains a segment characterised by a series of positively charged amino acids at every third position. This region designated S4 is likely to be the voltage sensor of the protein. In the brain, HCN3 and HCN4 exhibit subcortical distribution mainly concentrated in the hypothalamus and thalamus, respectively.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11010R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11010R-HRP
Lokale Artikelnummer::
BOSSBS-11010R-HRP
Beschreibung:
FAM84A is a 292 amino acid protein that belongs to the FAM84 family of proteins. Predominantly expressed in testis, FAM84A shares 44% amino acid identity with the related protein FAM84B. FAM84A localizes to a subcellular membrane region where there is no contact between neighboring cells and is believed to play a role in cell morphology and motility. More specifically, the expression of FAM84A increases cell motility. Two FAM84A isoforms are expressed due to alternative splicing events. Isoform 2 can be phosphorylated on various serine residues and this phosphorylation is associated with cellular morphology. FAM84A is upregulated in colorectal cancer, lung cancer, pancreatic cancer, cholangiocarcinoma and bladder cancer tissues. Via its ability to increase cell motility, FAM84A may contribute to the invasion and metastasis of cancer cells.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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