2-(3-(Trifluoromethyl)phenyl)propanoic+acid
Artikel-Nr:
(APOSOR480158-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR480158-1G
Lokale Artikelnummer::
APOSOR480158-1G
Beschreibung:
1-(2-Bromonaphthalen-1-yl)cyclopropane-1-carbonitrile
VE:
1 * 1 g
Artikel-Nr:
(APOSOR3117-50MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR3117-50MG
Lokale Artikelnummer::
APOSOR3117-50MG
Beschreibung:
5-(Pyridin-2-yl)thiophene-2-sulphonohydrazide
VE:
1 * 50 mg
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl 3-(4-iodopyrazol-1-yl)propanoate
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-(1H-Pyrrol-2-yl)acetonitrile
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-(1,2,3,4-Tetrahydroisoquinolin-1-yl)-1-naphthol
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3-(4-Iodopyrazol-1-yl)propanoic acid
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-(4-Chloropyridin-2-yl)ethanone 99%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
N-(1H-Indazol-7-yl)thiourea
Artikel-Nr:
(BOSSBS-3029R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3029R
Lokale Artikelnummer::
BOSSBS-3029R
Beschreibung:
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8170R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8170R-A680
Lokale Artikelnummer::
BOSSBS-8170R-A680
Beschreibung:
This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localised, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3029R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3029R-CY5.5
Lokale Artikelnummer::
BOSSBS-3029R-CY5.5
Beschreibung:
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9025R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9025R-CY3
Lokale Artikelnummer::
BOSSBS-9025R-CY3
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. ISLR2 (immunoglobulin superfamily containing leucine-rich repeat 2), also known as LINX (leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein), is a 745 amino acid single-pass membrane protein that contains five LRR repeats, one Ig-like (immunoglobulin-like) domain, a LRRCT domain and one LRRNT domain. ISLR2 exists as a homomultimer and is essential for axon extension during neural development. The gene encoding ISLR2 maps to human chromosome 15q24.1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5437R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5437R-A680
Lokale Artikelnummer::
BOSSBS-5437R-A680
Beschreibung:
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12312R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12312R-HRP
Lokale Artikelnummer::
BOSSBS-12312R-HRP
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 39 (LRRC39) is a 335 amino acid protein that contains nine LRR repeats and exists as two alternatively spliced isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12935R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12935R-FITC
Lokale Artikelnummer::
BOSSBS-12935R-FITC
Beschreibung:
Polyadenylation of mRNA precursors is a two-step reaction that requires multiple protein factors. The first step, endonucleolytic cleavage of polyadenylation substrates, requires CstF (cleavage stimulation factor), a heterotrimer that is composed of three distinct subunits. Heterotrimeric CstF recognizes GU- and U-rich sequences located downstream of the polyadenylation site on RNA. CstF-77 (cleavage stimulation factor, 77 kDa subunit), also known as CstF3, is one of the three subunits comprising CstF. It can exist as a homodimer and functions as the bridge, directly interacting with the other two CstF subunits, namely CstF-64 and CstF-50. CstF-77 is highly conserved among eukaryotes. It contains an Alpha-helical structure with 11 HAT (Half-a-TPR-containing) repeats and is essential for CstF assembly. In addition, CstF-77 is capable of interacting with CPSF1 and FCP1, other factors involved in polyadenylation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12935R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12935R-A680
Lokale Artikelnummer::
BOSSBS-12935R-A680
Beschreibung:
Polyadenylation of mRNA precursors is a two-step reaction that requires multiple protein factors. The first step, endonucleolytic cleavage of polyadenylation substrates, requires CstF (cleavage stimulation factor), a heterotrimer that is composed of three distinct subunits. Heterotrimeric CstF recognizes GU- and U-rich sequences located downstream of the polyadenylation site on RNA. CstF-77 (cleavage stimulation factor, 77 kDa subunit), also known as CstF3, is one of the three subunits comprising CstF. It can exist as a homodimer and functions as the bridge, directly interacting with the other two CstF subunits, namely CstF-64 and CstF-50. CstF-77 is highly conserved among eukaryotes. It contains an Alpha-helical structure with 11 HAT (Half-a-TPR-containing) repeats and is essential for CstF assembly. In addition, CstF-77 is capable of interacting with CPSF1 and FCP1, other factors involved in polyadenylation.
VE:
1 * 100 µl
Preis auf Anfrage
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